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Biomedical subjects

J Wada

Publications and source records attributed to J Wada.

At least 235 records · Page 13Linked to original sources

Long-term follow-up of artificial valves in patients under 15 years old.

Forty-nine artificial cardiac valves implanted in 44 patients less than 15 years old were reviewed. Out of 49 valves, 16 were mechanical and 33 were xenografts. Average follow-up was 2 years 5 months. Marked valvular stenosis developed in 11 out of the 33 xenografts, an incidence of 15% per patient-year. In patients with a xenograft valve, the incidence of sepsis was found to be 4% per patient-year and brain accidents, 4% per patient-year. In patients with mechanical valves, the incidence of stenosis was only 2% per patient-year and brain accidents, 2% per patient-year. There was no sepsis. From these follow-up results, mechanical valves seem to be superior to xenografts when used in patients less than 15 years old.

Adolescent↗

Long-term results of surgery on aortic valve diseases.

At the Heart Institute of Japan, Tokyo Women's Medical College, 474 aortic valve replacements (AVR) are performed using various kinds of prosthetic devices during the period of 1965, 5-1978, 12. Most popular valve prosthesis was Björk-Shiley valve totalling 215. 56 cases were subjected to study of more than 5 years follow up. They carried operative mortality of 16.1% and late mortality of 7.1%. Thromboembolism was 5.4%. 3 patients delivered 4 normal full term babies. There were 4 reoperations for aortic orifice with successful outcome. Cardiothoracic ratio, left ventricular strain pattern on ECG, blood pressure, pulmonary artery wedge pressure, cardiac indices, ejection fraction, end-diastolic volume have post-operatively returned almost to normal in majority of cases. Actuarial survival curve beyond 6 years after AVR was 98% up to 9 years.

Adolescent↗

Mucocutaneous lymph node syndrome. Successful aortocoronary bypass homograft in a four-year-old boy.

Mucocutaneous lymph node syndrome has been reported in more than 7,000 cases in Japan and other countries, and 1 to 2 percent of the patients died suddenly. This syndrome accompanied by coronary arterial aneurysm and thrombosis has been noted in postmortem examinations. The usual age is 1 to 1.5 years, and surgical subjects also include babies and infants. We report the findings in a four-year-old boy with this syndrome who was subjected to successful aortocoronary bypass grafting using his mother's fresh vein for homografting.

Child↗