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Biomedical subjects

J W Shore

Publications and source records attributed to J W Shore.

At least 73 records · Page 4Linked to original sources
PubMed1988

Choroidal malignant melanoma with early vitreous seeding.

Primary choroidal malignant melanoma with extension through the overlying retina is a rarely reported entity, and to our knowledge actual seeding of the vitreous has never been reported. The pathologic findings in a 41-year-old woman who presented with a large amelanotic subretinal mass near the optic disc of the right eye are discussed. Fundus examination preoperatively revealed a concentration of discrete, fleshy, oval to round, vitreous bodies of varying size, limited to the area overlying the mass. Histopathology of this tumor revealed a spindle cell posterior choroidal melanoma with marked atrophy of the overlying retina. At the apex, the retina was discontinuous and melanoma cells extended into the overlying vitreous. Some of the cells surrounded asteroid bodies overlying the tumor, altering their clinical appearance. This behavior, while only involving a small fraction of the tumor cells, may imply a more aggressive tumor.

Adult↗
PubMed1988

Scleral show.

Explore the source record for details and available documents.

Eyelids↗
PubMed1987

Linear nevus sebaceous syndrome.

The linear nevus sebaceous syndrome is a rare disorder first described in 1962 in two cases by Feuerstein and Mims. As originally described, it consisted of the triad of the characteristic midline facial linear nevus sebaceous of Jadassohn, seizures, and mental retardation. The authors have followed a patient with this syndrome from birth to age 8 and although he does demonstrate several neurologic and ocular abnormalities, he enjoys normal intelligence and has never suffered seizures. The features of this syndrome and several new ocular findings demonstrated in this case are described. Based on our long-term follow-up of this patient and our review of the reported cases to date, the authors suggest that the triad for this disorder should be changed to include the midline facial linear nevus sebaceous of Jadassohn, neurologic abnormalities which may, but not necessarily, include seizures and mental retardation, and ophthalmologic abnormalities.

Arachnoid↗
PubMed1987

Enophthalmos and upper eyelid retraction following osteoplastic frontal sinusotomy.

A 38-year-old man presented with hyperophthalmia, enophthalmos, and upper eyelid retraction 18 months following an osteoplastic flap and frontal sinus obliteration for mucocele. Computerized tomography confirmed the presence of frontal bone absorption in the roof of the orbit with traction and elevation of the orbital contents into the obliterated frontal sinus. A fracture of the orbital roof with penetration of periorbita at the time of original surgery was the suspected precipitating cause of the complication. Surgical management included lysis of the cicatrix between the orbit and frontal sinus and interposition of a silicone sheet between the orbit and sinus, which restored the appropriate anatomic relationships and prevented recurrence.

Adult↗
PubMed1987

Macrocystic enlargement of orbital dermis-fat grafts.

Acquired cysts represent an unusual but significant complication of orbital dermis-fat grafts. We report two cases of late postoperative enlargement of dermis-fat grafts: First, macrocystic enlargement occurring in both orbits with severe microphthalmia; second, cystic enlargement occurring in a dermis-fat graft for anophthalmia following an earlier evisceration. Both graft enlargements were due to epithelial-lined cysts that developed within the graft tissue. These cysts were treated by excising the cysts walls and allowing the resultant cavity to heal spontaneously. Light microscopy of the excised tissue revealed that the clear cysts were lined by a non-keratinizing, stratified squamous epithelium. The histogenesis of the cysts is unclear, but most likely they are the result of incompletely removed or implanted conjunctival or corneal epithelium. Several other possibilities are discussed. Due to the difficulty of removing all corneal and conjunctival epithelium, cystic complications of dermis-fat grafts make unattractive their use for volume enhancement in patients with microphthalmia or following evisceration.

Adipose Tissue↗
PubMed1987

The fornix approach to the inferior orbit.

The fornix or transconjunctival approach to the orbital floor and inferior orbit provides excellent exposure for the surgeon managing orbital fractures. The technique is ideally suited for patients with isolated blowout fractures; however, it can be combined with other surgical incisions to provide wide exposure of the inferior orbit, zygoma, and maxilla for the repair of more complex midfacial fractures. The surgical technique provides excellent access to the inferior orbit for biopsy or excision of orbital tumors and excellent opportunity for surgically augmenting orbits with posttraumatic enophthalmos or enophthalmos associated with anophthalmic sockets. Orbital decompression into the maxillary antrum and ethmoid sinus is easily accomplished through this incision. By avoiding a cutaneous incision in the lower eyelid, one reduces the risk for development of postoperative ectropion. During wound closure, the lower eyelid can be elevated and tightened and the canthal angle can be restored if necessary.

Eyelids↗
PubMed1986

Dermis-fat graft for orbital reconstruction after subtotal exenteration.

A surgical technique for reconstruction after subtotal orbital exenteration uses an autogenous dermis-fat graft. A musculocutaneous flap is advanced over the graft to provide the anterior vascular supply for the free dermis-fat graft. The periorbita and remaining orbital tissue provide the vascular supply posteriorly. This technique eliminates extensive skin grafting and delayed spontaneous healing. Wound healing is rapid and surgical morbidity is minimized. We have used this procedure in three patients with sebaceous gland adenocarcinoma, two patients with severe posttraumatic contracted sockets, and as a palliative procedure in one patient with a fungating choroidal melanoma and widespread metastasis.

Adipose Tissue↗
PubMed1986

Use of temporalis muscle flaps in complicated defects of the head and face.

Large defects in the upper two thirds of the face, skull, and skull base pose challenging reconstructive problems. There are a number of applicable reconstructive techniques, all with various advantages and disadvantages, available to otolaryngologists-head and neck surgeons. One method, originally described in the late 1800s, was evaluated by us. Applications of the technique included reconstruction of large defects of the forehead, dura, and anterior skull base, closure of orbital defects, and soft-tissue augmentation of the face. Advantages of this reconstructive technique are the flap's proximity to the defects and its simplicity of execution.

Adult↗
PubMed1986

The management of eyelid laxity during lower eyelid blepharoplasty.

Lower eyelid and lateral canthal angle malposition or frank ectropion are the most common complications of lower eyelid blepharoplasty. Although these complications may result from excessive skin excision, from surgical imbrication of the orbital septum or lower eyelid retractors, or from scar formation within the eyelid, failure to correct preexisting lower eyelid laxity is the most common cause. Recently published data have established laxity at the lateral canthus as the primary cause of involutional lower eyelid laxity. We review the pathophysiology of lower eyelid laxity and present an anatomic approach for the correction of lower eyelid laxity during blepharoplasty.

Aging↗
PubMed1986

Botulinum toxin for the treatment of essential blepharospasm.

Twenty-six patients with essential blepharospasm were treated with botulinum toxin by injection. The onset of protractor weakness in all patients ranged from one to five days following treatment. Maximal weakness developed within 12 days. There was a variable and gradual return of protractor strength over eight to 29 weeks in most patients and, with it, a return of spasm. Twenty-five patients received some degree of functional relief following initial injection. In most patients, however, the post-injection result could not be stabilized and repeat injections have been necessary to control recurrent spasms. There was one treatment failure. Three patients treated by injection following previous neurectomy and myectomy appeared to have a reduced requirement for subsequent injections. Complications included transient ptosis in six patients and mild exposure symptoms in four patients. Extraocular muscle paresis did not occur. There were no systemic side effects from the botulinum toxin injections.

Aged↗
PubMed1985

Changes in lower eyelid resting position, movement, and tone with age.

In a study of lower eyelid movement, resting position, and tone in 185 normal white patients ranging in age from 15 to 89 years, the mean vertical eyelid excursion from downgaze to upgaze was 5.29 mm. There was, however, a decrease in vertical eyelid movement with age of 0.05 mm/yr. The mean horizontal lower eyelid excursion with eyelid closure or gentle blink was 3.3 mm and horizontal eyelid movement decreased 0.015 mm/yr. The decrease in vertical and horizontal eyelid movement with aging was closely correlated with the increase in eyelid laxity in elderly patients (P less than .001). The lower eyelids of elderly patients rested against the globe at a position inferior to that of younger patients, a finding that correlated with increased eyelid laxity (P less than .001).

Adolescent↗
PubMed1985

Management of complications following dermis-fat grafting for anophthalmic socket reconstruction.

Sixty consecutive cases of dermis-fat grafts for anophthalmic socket reconstruction were reviewed to examine the frequency, severity, and management of postoperative complications. In seven patients, the conjunctiva failed to resurface the graft and central ulceration developed. Ten cases resulted in enophthalmos. Two patients developed keratinized sockets with chronic discharge and desquamation. Three patients required excision of conjunctival granulomas. One patient developed a primary graft infection. A donor site hematoma occurred in one patient. Secondary surgical intervention was required in ten patients. Nine complications in eight patients were managed in the office; five complications in four patients were observed and subsequently resolved without surgical intervention. Most complications occurred in patients with severely traumatized sockets who had undergone extensive earlier ocular surgery, or who had a systemic disease contributing to defective wound healing.

Adipose Tissue↗
PubMed1985

The management of the ptosis patient: Part I.

The various types of congenital and acquired ptosis are discussed as well as the findings on history and examination. From this information the appropriate operation can be chosen. Emphasis is placed on obtaining accurate and reproducible measurements in addition to assessing visual acuity, extraocular muscle movement, Bell's phenomenon, and tear secretion, especially in older patients. The operations described are the tarsal-Muller's muscle resection, levator aponeurosis advancement, levator resection, and frontalis suspension. Since the aim in ptosis surgery is symmetry in the primary position, overcorrections and undercorrections must occasionally be dealt with to achieve a satisfactory result.

Blepharoptosis↗
PubMed1984

Anatomic changes in involutional blepharoptosis.

Involutional blepharoptosis is a degenerative process involving the levator aponeurosis. Clinical and histopathologic evidence for involvement of the levator palpebrae superioris muscle has not been firmly established. We examined 20 patients with involutional blepharoptosis who demonstrated additional clinical, anatomic, and histopathologic findings consisting of a dehiscence of the medial limb of Whitnall's ligament, a lateral displacement of the tarsal plate of the upper eyelid, and a fatty degeneration of the levator muscle in the area of Whitnall's ligament. These findings suggest that a primary myopathic process may be involved in some cases of involutional blepharoptosis. The tarsal displacement complicates surgical correction of eyelids with blepharoptosis secondary to this myopathic process.

Aged↗
PubMed1984

Treatment of essential blepharospasm. I. Comparison of facial nerve avulsion and eyebrow-eyelid muscle stripping procedure.

Benign essential blepharospasm is an incurable disease for which many treatment modalities have been suggested. The two surgical procedures that have been used most commonly are avulsion of the facial nerve and stripping of the protractor muscles of the eyelid and brow. We compare two matched series of 22 patients; one group underwent facial nerve avulsion ("Reynold's" procedure), and the other underwent "muscle stripping" ("Anderson's" procedure). We noted the number of procedures required for the patient to obtain a functional visual result and the side effects produced. Additional surgical procedures required by patients undergoing facial nerve avulsion were additional facial nerve avulsion, repair of ectropion, and correction of dermatochalasis and brow droop. Additional procedures required in patients who had muscle stripping were excision of lower lid orbicular fibers or residual brow fibers. The Reynold group required 16 additional procedures (38 separate procedures) to obtain functional results, as opposed to the four additional procedures (26 separate procedures) required in the Anderson group. Two patients in the Reynold group who needed surgery have not yet undergone it at this writing. If they did, that would boost the total number of procedures to 40. Secondary procedures are needed 4.5 times more often with the Reynold procedure than with the Anderson procedure. The patient's subjective response to and acceptance of the procedure are much greater for the Anderson procedure.

Adult↗
PubMed1983

A simple methods of instant close-up photography.

In the ophthalmic examination, photographs document both normal and pathologic findings in patients. Thus, they constitute an invaluable part of the medical record. High-quality external photographs, produced quickly and inexpensively, are particularly helpful as a surgeon's reference in blepharoplasty, blepharoptosis correction, and other oculoplastic procedures. Instant-camera photography is also useful in the evaluation of ocular motility and neuro-ophthalmic disorders.

Humans↗
PubMed1983

Avoidance of complications in lower lid blepharoplasty.

The most common complication of lower lid blepharoplasty is lower lid malposition either lower lid retraction or frank ectropion. This is caused by the vertical pull of skin shortage or shrinkage on a lax tarso-ligamentous sling. A method of tightening the tarso-ligamentous sling combined with a lower lid blepharoplasty is presented. An alternate method of lower lid fat removal through the fornix without skin incision is presented to be used in patients with taut lower lid skin.

Adipose Tissue↗