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J W Segura

Publications and source records attributed to J W Segura.

At least 19 recordsLinked to original sources
PubMed1995

Laparoscopic left adrenalectomy for aldosteronoma: early Mayo Clinic experience.

OBJECTIVE: To evaluate early results with laparoscopic left adrenalectomy in patients with an aldosteronoma. DESIGN: We retrospectively reviewed the medical records to Mayo patients in whom laparoscopic left adrenalectomy had been attempted for presumed aldosteronoma. MATERIAL AND METHODS: Data on the diagnosis, details about the procedure, occurrence of associated complications, and duration of recovery period were analyzed for all study patients. RESULTS: Of the nine patients who underwent attempted laparoscopic left adrenalectomy, seven had aldosteronoma. In six of the seven patients, the procedure was successful. No preoperative mortality occurred, and morbidity was limited to prolonged ileus in one patient. Of the other five patients with successful results, all tolerated liquids within 24 hours after the procedure. The mean postoperative hospital stay for the six patients with successful laparoscopic procedures was 2.3 days, and four patients were dismissed within 48 hours after the procedure. CONCLUSION: Laparoscopic adrenalectomy is a safe alternative for the management of aldosteronoma of the left adrenal gland.

Adrenal Cortex Neoplasms↗
PubMed1995

Efficacy of a new endoureterotomy balloon for the treatment of benign ureteral strictures using the porcine model.

OBJECTIVES: Endoureterotomy and balloon dilation are techniques that have shown promise as treatment modalities for benign ureteral stricture disease. In this animal investigation, the results of a new endoureterotomy balloon that simultaneously incises and dilates the ureteral stricture via a retrograde approach are discussed. METHODS: Using the female pig model, 9 subjects with benign ureteral strictures were treated: 7 with the endoureterotomy balloon and 2 with balloon dilation only. RESULTS: Success based on radiologic parameters and Whitaker testing was obtained in 5 of the 7 animals treated by endoureterotomy. In both animals treated by balloon dilation only, recurrent ureteral stricture disease developed. CONCLUSIONS: This preliminary investigation suggests that this new device may be an effective treatment for benign ureteral stricture disease and that the further study in clinical trials is warranted.

Animals↗
PubMed1995

Nephron-sparing laparoscopic surgery: techniques to control the renal pedicle and manage parenchymal bleeding.

Laparoscopic nephron-sparing surgery has been limited by several factors, including problems in the control of the vascular pedicle and the management of parenchymal bleeding. In an effort to improve the efficacy of laparoscopic nephron-sparing surgery, we developed and tested several techniques to control and manage intraoperative renal bleeding while performing 30 laparoscopic anatrophic nephrolithotomies using the porcine model. Control of the renal pedicle and management of bleeding included the use of the following: (1) extracorporeally applied atraumatic vascular pedicle clamp; (2) Argon Beam Coagulator to perform the capsulotomy; (3) electrocautery scissors to perform the nephrotomy; (4) Gelfoam welded to the cut surface of the parenchyma with the argon beam coagulator; (5) Surgicel welded to the outer surface of the kidney with the Coagulator; and (6) laparoscopically applied bolster sutures to further stabilize the renal unit. All animals tolerated the procedure well and survived to their appointed date of sacrifice. We conclude that these techniques may improve the efficacy of laparoscopic renal surgery, including nephron-sparing procedures.

Animals↗
PubMed1995

Ureteropelvic junction obstruction with a simultaneous renal calculus: long-term followup.

We reviewed 111 patients who presented with simultaneous renal calculi and a ureteropelvic junction obstruction. Of 34 patients with ureteropelvic junction obstruction and a coexisting struvite stone 62% had recurrent calculi. The use of antibiotics significantly affected the incidence of recurrent struvite calculi. In particular, if prolonged prophylactic antibiotics (greater than 3 months) were used 15% of the patients had recurrent stones, compared to 90% if only perioperative antibiotics (less than 15 days) were used (p < 0.001). Patients with ureteropelvic junction obstruction and coexisting nonstruvite calculi were treated by either observation alone (53) or metabolic evaluation with appropriate intervention (24). Metabolic evaluation of patients with nonstruvite calculi revealed that 76% had an identifiable metabolic abnormality, treatment of which significantly decreased the incidence of recurrent renal calculi: 17% of the patients on interventional therapy had recurrent stones compared to 55% treated by observation alone (p < 0.001).

Anti-Bacterial Agents↗
PubMed1995

Percutaneous antegrade endopyelotomy: review of 50 consecutive cases.

Between 1988 and 1993, 50 percutaneous antegrade endopyelotomies were performed for ureteropelvic junction obstruction at this institution. The success of the procedure was based on radiological parameters as well as patient symptomatology. The overall success rate of the procedure was 88%. Endopyelotomy was successful in 9 of 11 patients (82%) who presented after failing previous renal procedures. When endopyelotomy was used as the initial treatment modality the success rate was 90%. These results support the argument that endopyelotomy should be considered as first line therapy for most adults with ureteropelvic junction obstructions [corrected].

Adolescent↗
PubMed1994

Surgeon's role in the management of solitary renal cell carcinoma metastases occurring subsequent to initial curative nephrectomy: an institutional review.

BACKGROUND: Solitary metastases from a primary renal cell carcinoma (RCC) occur in < 10% of patients with metastatic RCC. To date, the benefit of surgically resecting such apparently solitary lesions has not been well documented. MATERIALS AND METHODS: Forty-one patients (25 men, 16 women) with metastatic renal cell carcinoma treated by surgical excision of solitary metastases (1970-1990) were retrospectively reviewed. They comprised 9% of patients with metastatic hypernephroma seen during this period. All patients had undergone previous curative nephrectomy with a median disease-free interval of 27 months. Patients with skeletal, spinal cord, and lymph node metastases were excluded. RESULTS: Metastases were intrathoracic (n = 20), intracranial (n = 7), and intraabdominal or in the extrapleural chest wall soft tissue (n = 10). Three patients had metastases to the thyroid gland and one had a solitary metastasis to an index finger. Median follow-up was 3.2 years. Complete resection was possible in 36 patients (88%) with a single lesion excised in 23 of these 36 patients (64%). There was no operative mortality. Predicted survival from the date of complete resection of metastases was 77%, 59%, and 31% at 1, 3, and 5 years, respectively, with a median survival of 3.4 years. One patient is alive without evidence of recurrent tumor 93 months from the first of 12 complete surgical resections. Varying adjuvant therapy was used in 50% of the patients. An increased histological tumor grade of the metastatic lesion relative to the original RCC was the only significant prognostic indicator identified. Disease-free interval and number of resected lesions were not significantly associated with patient survival. CONCLUSION: A small fraction of renal cell carcinoma patients are candidates for potentially curative surgical resection of solitary metastatic lesions. Excision of such lesions may contribute to prolonged survival in selected instances.

Adult↗
PubMed1994

Stones.

Explore the source record for details and available documents.

Humans↗
PubMed1992

Transurethral microwave thermotherapy for prostatism: early Mayo Foundation experience.

As part of a multicenter investigative trial, transurethral microwave thermotherapy of the prostate was used in 60 men with symptomatic benign prostatic hypertrophy. A single office treatment on the Prostatron, a device that provides concurrent microwave heating of the prostate and conductive cooling of the urethra, was well tolerated and caused no major adverse events. Symptomatic improvement, especially the decrease in nocturia and urgency, was dramatic, and urinary flow was improved at 6 weeks. Continued follow-up suggests that further improvement will be achieved and that transurethral microwave thermotherapy has a role in the treatment of benign prostatic hypertrophy.

Academic Medical Centers↗
PubMed1991

National High Blood Pressure Education Program (NHBPEP) review paper on complications of shock wave lithotripsy for urinary calculi.

This decade has witnessed dramatic advances in the surgical management of urinary calculi. Today, most stones can be removed by minimally invasive means. In fact, the treatment of choice in 60% to 90% of patients with renal and ureteral calculi that need to be surgically removed is extracorporeal shock wave lithotripsy (ESWL). This article reviews indications for ESWL and discusses deleterious effects of ESWL.

Animals↗
PubMed1991

Early experience with percutaneous cholecystolithotomy.

Percutaneous cholecystolithotomy should be added to the list of alternatives to elective open cholecystectomy for the management of patients with gallstones. Our initial experience with percutaneous cholecystolithotomy in 13 patients (7 men and 6 women who ranged in age from 47 to 83 years) demonstrated that the procedure could be accomplished successfully with acceptable morbidity and no mortality. After a mean duration of follow-up of 10.7 months, only one patient had recurrent cholelithiasis. Because of rapid changes in the therapeutic approach to patients with cholelithiasis, percutaneous cholecystolithotomy may seldom be used.

Aged↗
PubMed1990

Branched, struvite calculus and clear cell carcinoma in same kidney. Rare condition with significant implications for management.

The concomitant existence of a branched (partial staghorn) calculus and clear cell carcinoma (hypernephroma) in the same kidney is rare. Herein, we report the eighth such case in the world literature, and to our knowledge, the first patient with a parenchymal tumor identified preoperatively. In all of the previous 7 cases, the calculus was managed with open renal exploration, and only at the time of surgery was the incidental renal cell carcinoma identified; the surgical procedure was modified accordingly. With open surgery no longer the cornerstone of therapy for renal calculi, it is imperative that the kidney be evaluated in a meticulous and compulsive manner prior to extracorporeal shock wave lithotripsy (ESWL) or percutaneous nephrolithotomy (PNL). The finding of a coexisting renal cell carcinoma will radically alter the patient's treatment.

Adenocarcinoma↗
PubMed1990

Ureteroscopy in children.

The development of ureteroscopy has led to a dramatic change in the management of ureteral stones as well as other ureteral pathological conditions in adults. Until recently, size limitations have prevented the technique from being used in small children. We have used ureteroscopy for diagnosis and therapy in 4 children less than 10 years old. There was no significant morbidity from the procedure in our patients.

Child↗
PubMed1990

Technical consideration in radical retropubic prostatectomy: blood loss after ligation of dorsal venous complex.

The estimated blood loss and blood transfused in 641 patients undergoing bilateral pelvic lymphadenectomy and radical retropubic prostatectomy were analyzed to compare ligation and nonligation of the deep dorsal venous complex. Group 1 (325 men) had no attempt at deep dorsal vein ligation and group 2 (316) had ligation of the deep dorsal venous complex. Group 2 was subdivided into group 2a-137 men in whom an attempt at a nerve-sparing procedure was made and group 2b-179 in whom no such attempt was made. Estimated intraoperative blood loss was significantly different between the groups: group 1--mean loss 1,262 ml. and group 2--mean loss 1,020 ml. (p less than 0.0001). The amounts of blood transfused intraoperatively were significantly different: group 1-1.73 units and group 2-1.21 units (p less than 0.0002). Intraoperative blood loss was not significantly different between subgroups 2a and 2b but the mean amount of blood transfused intraoperatively was lower in group 2a than in group 2b (0.99 and 1.39 units, respectively p less than 0.02). The greatest amounts of blood lost and transfused were in group 1 (no ligation) and the least amounts were in group 2a (ligation and nerve-sparing), representing highly statistically significant differences (p less than 0.0001).

Adenocarcinoma↗
PubMed1990

Safety of same-day sequential extracorporeal shock wave lithotripsy and dissolution of gallstones by methyl tert-butyl ether in dogs.

Passage of stone fragments after extracorporeal shock wave lithotripsy (ESWL) of gallstones has resulted in biliary colic, duct obstruction, and pancreatitis in some patients. Rapid dissolution of these fragments with methyl tert-butyl ether (MTBE) may prevent such side effects and achieve complete clearance of gallstones within hours rather than several months to a year or longer. This study examines the safety of same-day ESWL fragmentation and MTBE dissolution of surgically implanted human gallstones in 15 dogs. The animals were randomly assigned to one of four treatment groups to assess MTBE absorption from the gallbladder and to observe hematology and chemistry profiles after 0, 400, and 1,200 shock waves from a lithotriptor followed by MTBE dissolution therapy. They were sacrificed either immediately after treatment (12 dogs) or 2 weeks later (3 dogs). The results demonstrated that although ESWL causes moderate trauma to the gallbladder, this did not result in increased MTBE absorption or histologic evidence of mucosal disruption. Blood profiles demonstrated an increase in only the level of aspartate aminotransferase. The three dogs that were sacrificed 2 weeks after the combined treatment had no residual evidence of gallbladder injury or remaining stone material. In all animals, severe injury occurred where shock waves passed through lung or air-filled colon. This study suggests that same-day sequential fragmentation of gallstones by ESWL followed by dissolution of stone fragments with use of MTBE may be associated with only mild to moderate and reversible gallbladder trauma and can rapidly achieve clearance of gallstones.

Animals↗
PubMed1990

Current surgical approaches to nephrolithiasis.

Shock wave lithotripsy is the cornerstone of the modern management of surgical stone disease and is the procedure of choice for small stones in uncomplicated situations. As complexity increases and as the stone size increases, percutaneous lithotripsy becomes more important. Ureteroscopy is preferable for lower ureteral stones and is useful for many mid and upper ureteral stones. Occasional large, complicated stones, or stones that can be reached no other way, require open surgery. Successful management of a wide variety of patients with urinary calculi requires the recognition that multiple forms of therapy are necessary. Identification of the situations best managed by these different treatments will ensure optimal management of patients with surgical stone disease.

Humans↗
PubMed1990

Surgical management of urinary calculi.

Shock wave lithotripsy is the cornerstone of the modern management of urinary calculi and is the preferred treatment for most small renal stones. Percutaneous lithotripsy is preferred for large stones and in combination with ESWL for staghorn calculi. Upper ureteral stones should be pushed back to the kidney for ESWL, if possible; otherwise they should be treated in situ. Lower ureteral stones are preferentially managed with ureteroscopy, but ESWL may also be used. A variety of methods of power lithotripsy are available: ultrasound, electrohydraulic lithotripsy, and pulsed dye laser lithotripsy. Only 1% to 2% of stone patients require open surgery; it is an important judgment to identify these patients to avoid inappropriate use of newer techniques in cases where success is unlikely. It is apparent that modern management of the patient with a urinary calculus requires access to all methods of stone removal. The surgeon and internist should not forget that the goal is to remove the stone safely, efficaciously, and economically.

Endoscopy↗
PubMed1990

Role of percutaneous procedures in the management of renal calculi.

Appropriate management of the variety of patients with stone disease demands access to all methods of stone removal. Percutaneous procedures are an integral aspect of the surgical management of stone patients, and the urologist must recognize when a patient's situation is best served by percutaneous surgery. Percutaneous stone removal procedures are preferred when: 1. The stone is large, i.e., greater than 2 to 3 cm. 2. The stone is staghorn in configuration, with percutaneous measures being used either as primary treatment or in combination with shock wave lithotripsy. 3. The stone is composed of cystine 4. When certain removal of the stone is important. 5. When there is obstructive uropathy. 6. When other modalities have failed. 7. In morbidly obese individuals and others whose body habitus precludes use of the shock wave machine. 8. In children, at least until the issue of long-term safety of extracorporeal lithotripsy is settled.

Adult↗