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Biomedical subjects

J W Seeds

Publications and source records attributed to J W Seeds.

78 records · Page 5Linked to original sources

Rocky Mountain spotted fever in pregnancy: differential diagnosis and treatment.

Rocky Mountain spotted fever (RMSF) presents both diagnostic and therapeutic difficulties in the pregnant patient. Early clinical manifestations may be mistaken for normal pregnancy changes. Accurate diagnosis is essential, since several of the disorders in the differential diagnosis may have important obstetric implications. Antibiotics generally used to treat serious infections during pregnancy are ineffective in treating RMSF. Chloramphenicol is the antibiotic of choice. Specific recommendations for evaluating pregnant patients with suspected RMSF are given.

Chloramphenicol↗

Relationship of fetal limb lengths to both biparietal diameter and gestational age.

Ultrasonic long bone imaging is a potentially valuable index of fetal growth. Reported here are fetal limb measurements in normal pregnancies, produced with readily available ultrasound equipment and described using simple statistical techniques. Lengths of femur, humerus, tibia/fibula, and radius/ulna are related to gestational age. Femur and humerus measurements are also related to biparietal diameter. Linear correlation is high and with few exceptions these results confirm those of other investigators. Comparability between these data and previously published work is examined and the utility of these standards of growth discussed. Long bone imaging is confirmed as being reliable, reproducible, and a viable alternative to the measurement of biparietal diameter in the biophysical assessment of fetal development.

Anthropometry↗

Early prenatal sonographic appearance of rare thoraco-abdominal eventration.

Fetal ventral wall malformations may be diagnosed prenatally with ultrasound. These include omphalocele, gastroschisis, or even thoracic defects with or without ectopia cordis. It is important whenever such a defect is found to carefully define the full extent of the lesion prior to parental counselling. Described and illustrated here is the prenatal diagnosis with real-time ultrasound at 17 weeks gestation of a rare thoraco-abdominal ventral wall defect including omphalocele, bifid sternum, diaphragmatic aplasia, and pericardial aplasia with incomplete ectopia cordis. The technique is described and the importance of the complete, accurate delineation of anatomic malformations is emphasized.

Abdominal Muscles↗