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Biomedical subjects

J W Ross

Publications and source records attributed to J W Ross.

At least 91 records · Page 5Linked to original sources

Medical, judicial, and statutory regulation of ECT in the United States.

The standards for ECT recommended by an APA task force report and those embodied in federal court orders and state statutes and regulations are compared. The authors conclude that there is serious boundary and role confusion owing to progressive intrusion of state authority into areas traditionally held to lie in the domain of medical judgment and clinical care. In spite of comprehensive safeguards promulgated by the psychiatric community, overregulation by legislatures and courts is commonplace, interposing law between physicians and patients and resulting in delays or denials of service while failing to resolve critical legal issues involving competence and consent.

Adolescent↗

Immunocytochemical demonstration of human proinsulin chimeric polypeptide within cytoplasmic inclusion bodies of Escherichia coli.

Immunocytochemical techniques were used to identify human proinsulin chimeric protein in cytoplasmic inclusion bodies of genetically modified Escherichia coli. Antibodies to proinsulin chimeric protein (human proinsulin coupled at its amino-terminus to a portion of the E. coli tryptophan E gene product) were localized in E. coli using post-embedding staining with protein A-peroxidase labelling for transmission electron microscopy. The observable distribution of the labelled antibody was limited to that portion of the E. coli cytoplasm occupied by inclusion bodies. The localization of human peptides as insoluble masses within the bacterial cytoplasm has important implications in relation to the synthesis, recovery and purification of pharmacologically useful substances produced through the application of recombinant DNA technology.

Bacterial Proteins↗

The role of the social worker with long term survivors of childhood cancer and their families.

The number of long term survivors of childhood cancer is increasing and these patients and their families benefit from the social worker's attention to their immediate as well as future needs and concerns. Periods of extended remission can be differentiated in terms of the demands made on family and patient at each juncture. Since long term survival is still a recent phenomenon, reports of clinical observations and research are limited. Some typical reactions are discussed with suggested social work interventions. A developmental approach to the patient is desirable.

Adaptation, Psychological↗

Regulation of quality in the clinical laboratory.

Effective regulation of quality is the responsibility of the individual laboratory. In this article, the author explains why coordination and centralization in a quality control program is necessary, that it is a management process, and that regulation begins with a definition of performance standards.

Health Facilities↗

Analytic clinical laboratory precision. State of the art for selected enzymes.

Results of precision estimates are reported for selected enzyme analytes. Laboratories that participated in regional quality control programs supplied data to a centralized data processing service (College of American Pathologists Computer Center). These data, representing several regional groups which used different commercial sources of control serum, were statistically analyzed by regression of coefficient of variation (CV) upon concentration of analyte using a modified polynomial regression technic. Tolerance limits for long-term within-laboratory precision were developed from this data. Estimated CVs were extracted at selected analyte concentrations, and tolerance limits for CVs at these concentrations were developed. In addition, selected individual methods within the larger groups were individually examined to evaluate effect of control material matrix upon clinical estimates of enzyme precision. Differences in selected method groups are discussed.

Alanine Transaminase↗