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Biomedical subjects

J W Martin

Publications and source records attributed to J W Martin.

106 records · Page 6Linked to original sources

Angiosarcoma metastatic to the maxillary tuberosity gingiva.

A case of angiosarcoma metastatic to the maxillary gingiva is presented. A review of the literature and an epidemiologic survey of angiosarcoma cases since 1944 at the M. D. Anderson Hospital and Tumor Institute prove this to be an extremely rare occurrence. Generally, metastasis to the oral/perioral tissues occurs as a late sequela secondary to diffuse metastatic disease. In this case, however, two extensive metastatic tumor surveys determined that the only metastasis was to the oral site. The lesion clinically mimicked an inflammatory process. It is hoped that this presentation will reinforce aggressive pursuit of innocuous-appearing oral lesions when the patient has a history of malignant disease and will further encourage dental involvement in the oral/dental assessment and are of the cancer patient.

Bone Neoplasms↗

A32390A, a new biologically active metabolite. II. Isolation and structure.

An inhibitor of dopamine-beta-hydroxylase, designated A32390A, was isolated from the culture broth of a Pyrenochaeta species. The inhibitor showed antimicrobial activity against fungi and gram-positive bacteria. Spectroscopic analysis and chemical degradation studies indicated that the structure was 1,6-di-O-(2-isocyano-3-methylcrotonyl)-D-mannitol.

Animals↗

Carcinoma of the thyroid gland. A 15-year survey in private hospitals in Sacramento.

All cases of carcinoma of the thyroid gland diagnosed at two large hospitals in Sacramento during the 15 year period 1951-1965 were studied. Of the 232 cases diagnosed, 179 or 77.2 percent were papillary carcinoma. It was possible to trace 94 percent of all the patients, with a median follow-up of 6.5 years, and no deaths due to papillary carcinoma of the thyroid were found. The extent of operation did not appear to influence the course of papillary carcinoma of the thyroid.

California↗

Aplastic anaemia.

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Anemia, Aplastic↗

Pedi-pack transfusion in a newborn intensive care unit.

Two hundred and ninety-one transfusions using 221 pediatric frozen red blood cell packs (Pedi-Packs) were given to 141 newborn babies and infants in the newborn intensive care unit. In 18 patients, 47 transfusions were studied for transfusion and clinical characteristics. Two possible hemolytic episodes are described in detail and remain unexplained. Blood loss for laboratory tests was found to average 3.1 ml/kg per day spent in the newborn intensive care unit. The rise in hematocrit was found to be excellent. Overall, the transfusion of thawed pediatric red blood cell packs was found to be convenient, safe and effective. Because of pretesting possibilities with the use of this source of red blood cells, one of the problems associated with a walking donor program is eliminated.

Anemia↗

Back pain in industry. A prospective survey.

Eight hundred and two subjects employed in N.W. England have been interviewed and examined after episodes of back or sciatic pain, using a standardized procedure. Data on recurrence of symptoms leading to further treatment or absence from work in the following two 12-month periods were obtained by postal questionary. Residual pain in the leg and a number of positive clinical signs of return to work, longer sickness--absence for the current attack, and two or more previous attacks were all associated with recurrence or persistence of symptoms. The prognosis also varied according to the cause of back pain, falls being associated not only with longer periods of absence in the current attack but with a higher rate of recurrence. The results have underlined the significance of a thorough examination on return to work after back pain for the industrial medical officer, as well as the epidemiological importance of this phase in the natural history of back and sciatic pain.

Absenteeism↗

Rehabilitation of a patient with limited oral opening following glossectomy.

Rehabilitation of the glossectomy patient is one of the most difficult and challenging problems for the prosthodontist and speech pathologist. The tongue plays an important role in articulation, control of secretions, formation of a bolus, propulsion of the bolus toward the pharynx, clearing the palate, and initiation of the swallow reflex. This paper presents speech and prosthodontic considerations for a patient who underwent a glossectomy and had the additional problem of reduced oral opening.

Aged↗

Prosthodontic and surgical considerations for pediatric patients requiring maxillectomy.

The quality of treatment and rehabilitation for the head and neck cancer patient, especially the pediatric patient, has progressed markedly over the years due to the cooperation of specialists involved in the total care of the patient. Defects of the oral cavity caused by trauma or removal of malignant or benign tissue require special treatment considerations with the pediatric patient. Aside from radiation and chemotherapy, other forms of adjuvant therapy, such as physical therapy, and patient and family counseling, are needed for proper rehabilitation. In addition, oral hygiene is essential in the overall rehabilitative process. Pediatric dental, orthodontic, prosthodontic, and oral and maxillofacial surgery specialties become integrated in treating the pediatric patient. The concentrated multidisciplinary treatment reduces post-treatment morbidity by shortening recovery and immediate rehabilitation time and by providing long-term care during the critical growth period.

Adolescent↗

Cigarette smoking, physical fitness, and injuries in infantry soldiers.

Reliable data on the impact of physical training on light infantry units in terms of injuries and time loss are sparse. This study evaluated a light infantry unit (n = 181) prospectively and followed it throughout one year of infantry training and operations. Fifty-five percent of the soldiers (n = 101) experienced one or more injuries. Eighty-eight percent of the injuries were training-related conditions, which resulted in 1,103 days of limited duty. Lower extremity overuse injuries were the most common type of injury documented. Fractures accounted for the greatest number of days of limited duty. Risk factors for training-related injuries identified by this study were cigarette smoking, high percentage of body fat, extremely high or low body mass index, low endurance levels, and low muscular endurance levels (sit-ups). Logistic regression showed that cigarette smoking and low endurance levels were independent risk factors for training injuries. These data indicate that the incidence of training-related injuries in infantry units is high. A number of modifiable injury risk factors were identified, suggesting that many of these injuries may be preventable.

Adult↗

Nodular subcutaneous histoplasmosis. A case report with diagnosis by fine needle aspiration biopsy.

Fine needle aspiration biopsy (FNAB) of a solitary subcutaneous nodule in the upper arm of a patient being treated with corticosteroids for chronic obstructive pulmonary disease contained numerous spherical, unstained, refractile particles mixed with necrotic cellular material and rare intact histiocytes with yeastlike inclusions. The morphology of the extracytoplasmic spheroids and cytoplasmic inclusions, as demonstrated with Gomori methenamine silver stain, was characteristic of Histoplasma capsulatum var capsulatum. This organism's identification was confirmed by excisional biopsy and microbiologic testing. If the characteristic intrahistiocytic, yeastlike forms are rare or absent, recognition of this peculiar, uncommonly encountered extracellular pattern is crucial to the diagnosis of infection with H capsulatum. This pattern may become more common with increased numbers of immunosuppressed patients and increased use of FNAB.

Aged↗

Rehabilitation of a midface defect with reconstructive surgery and facial prosthetics: a case report.

This paper reports a case in which reconstruction of a midface defect was accomplished by using microvascular surgery with free tissue transfer of the fibula for a 55-year-old man with squamous cell carcinoma in the nasal vestibule and nasal wall. This technique was developed and first used to reconstruct mandibular defects. Using a surgical template during the midface reconstruction can help the surgeon place the graft in a position that will complement the definitive facial prosthesis, as illustrated in this report.

Carcinoma, Squamous Cell↗