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Biomedical subjects

J W Estes

Publications and source records attributed to J W Estes.

At least 37 records · Page 2Linked to original sources
PubMed1980

Carotid artery surgery without a temporary indwelling shunt. 1,917 consecutive procedures.

One thousand nine hundred seventeen consecutive carotid artery operations were performed in which the carotid artery was clamped for as long as necessary to accomplish a revascularization procedure. Those patients adversely affected by failure to use a shunt were identified. Results of a statistical analysis of stroke morbidity when compared with the literature show that the use of an intraoperative temporary shunt does not offer improved results in carotid artery surgery.

Adult↗
PubMed1972

The heterogeneity of the anticoagulant response to heparin.

Difficulties in evaluating the anticoagulant effect of heparin led to studies of the rate of disappearance of its effect on the whole body partial thromboplastin time, and of its simultaneously bioassayed plasma concentration. The slope of the anticoagulant's dose-effect curve varied with each subject's baseline coagulation status, which probably accounts for the wide range of clinically observed responses to the drug. The mean rate of disappearance of bioassayed heparin was less than the mean rate of disappearance of the drug's effect on the clotting time, probably because of heparin's extensive binding to the plasma proteins which comprise its site of action. That these two kinds of rate of disappearance were found not to be correlated may also reflect the protein-binding capacity of heparin.

Binding Sites↗
PubMed1970

Genetic counselling.

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Chromosome Aberrations↗