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Biomedical subjects

J W Blackburn

Publications and source records attributed to J W Blackburn.

7 recordsLinked to original sources

The Dalhousie University experience of training residents in many small communities.

BACKGROUND: Dalhousie University Faculty of Medicine provides a fully integrated postgraduate medical education program that prepares both primary care and other specialist physicians. Training takes place in many urban and rural communities. METHOD: In 1991-92 reviews were undertaken of the practice locations of (1) the 200 graduates of primary care residencies between 1987 and 1991 who were licensed to practice in one of the four Atlantic provinces and (2) the 371 graduates of other specialty residences between 1981 and 1991, regardless of practice location but including only those programs with more than ten graduates. The graduates of primary care programs had received training in either one-year rotating internships or two-year family medicine programs. RESULTS: Of the primary care trainees, 130 (65%) remained in practice in Atlantic Canada; of these trainees, 74 (57%) had practices in rural locations. For the other specialist trainees, 50% or more of those with practices in the Atlantic provinces practiced in rural locations in the following specialties: general surgery, internal medicine, ophthalmology, and otolaryngology. CONCLUSION: Postgraduate medical education at Dalhousie is somewhat unusual in that all first-year trainees are required to spend time in a small community as part of their training; hence, students who choose programs at Dalhousie often do so because of their interest in experience in a variety of communities, including those outside metropolitan areas. Still, it was surprising that graduates of some non-primary-care specialty programs, in addition to the graduates of the primary care programs, tended to choose rural practice locations. The site of postgraduate training appears to be one of the important factors in the selection of practice locations.

Education, Medical, Graduate↗

The impact of biochemistry, bioavailability and bioactivity on the selection of bioremediation techniques.

A wide range of bioremediation strategies is being developed to treat contaminated soils. Selecting the most appropriate strategy to treat a specific site can be guided by considering three basic principles: the amenability of the pollutant to biological transformation to less toxic products (biochemistry); the accessibility of the contaminant to microorganisms (bioavailability); and the opportunity for optimization of biological activity (bioactivity).

Biochemical Phenomena↗

Dynamic response of naphthalene biodegradation in a continuous flow soil slurry reactor.

Periodic perturbations were used to evaluate the system stability and robustness of naphthalene biodegradation in a continuous flow stirred tank reactor (CSTR) containing a soil slurry. The experimental design involved perturbing the test system using a sinusoidal input either of naphthalene or non-naphthalene organic carbon at different frequencies during steady state operation of the reactors. The response of the test system was determined by using time series off-gas analysis for naphthalene liquid phase concentration and degradation, total viable cell counts, and gene probe analysis of naphthalene degradative genotype, and by batch mineralization assays. Naphthalene biodegradation rates were very high throughout the experimental run (95 to greater than 99% removed) resulting in very low or undetectable levels of naphthalene in the off-gas and reactor effluent. Attempts to reduce the rate of naphthalene biotransformation by either reducing the reactor temperature from 20 degrees C to 10 degrees C or the dissolved oxygen level (greater than 1 mg/L) were unsuccessful. Significant naphthalene biodegradation was observed at 4 degrees C. While variable, the microbial community as measured by population densities was not significantly affected by temperature changes. In terms of naphthalene biotransformation, the system was able to adapt readily to all perturbations in the reactor.

Biodegradation, Environmental↗

Tax reform.

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Humans↗