Biomedical subjects
Publications and source records attributed to J Vomela.
As a cause of septic shock, peritonitis biliaris is a very serious condition. We stress the risks of its development and necessity of postoperative drainage in laparoscopic cholecystectomy. The risks include a cholascos which may develop after some radical procedures of a "non-operative" nature on the liver parenchyma and bile passages (transperietal or endoscopic procedures).
Experimentally tested technique of alleviated oesophageal anastomosis proved a significantly positive effect on the process of healing of the oesophageal anastomosis after previous resection. Hitherto accomplished research proved the great asset of this technique as regards strength and optimal conditions for the postoperative stage of healing.
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The haemodynamic response to premature excitation was studied in open-chest dog hearts. Intraventricular pressure, dP/dt and outflow rate of the left and right heart (5 experiments each) were compared at variable preextrasystolic intervals and with the stimulation at three different sites (left ventricle--LV apex and base, right ventricle--RV free wall). In both ventricles and at any driving interval the reduction of all extrasystolic parameters is significantly more pronounced on ipsilateral stimulation. This reduction is apparent even at the fusion interval, demonstrating the importance of normal spread of excitation. The differences between apex and base stimulation are, however, only insignificant. The outflow valves opening interval greatly differs in aorta and pulmonary artery, namely if LV is stimulated, which results in a considerable disproportion between LV and RV extrasystolic stroke volumes. The extrasystolic augmentation is revealed by all parameters in the right heart but is surprisingly absent in the peak pressure and relaxation rate (dP/dt) in the LV.
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In patients with urinary bladder carcinoma, the intravesical BCG instillation is widely used. We present two cases of severe pulmonary afflictions developed during this treatment. The possible mechanisms of etiology are discussed and the classification of the intravesical BCG treatment side effects is suggested.