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Biomedical subjects

J Villarreal

Publications and source records attributed to J Villarreal.

25 records · Page 2Linked to original sources
PubMedDate not supplied

Cerebral cysticercotic arteritis: detection and follow-up by transcranial Doppler.

Intracranial arteritis is a well-known complication of cerebral cysticercosis. The aim of this study was to explore the possible role of transcranial Doppler (TCD) in the evaluation of cysticercotic arteritis in 9 patients with subarachnoid cysticercosis and stroke. Arteritis of main basal vessels was detected by TCD in 7 of 10 arterial lesions that were demonstrated by cerebral angiography. The Doppler pattern was occlusive in 2 cases and stenotic in 5. In the 3 patients with lacunar infarcts, both cerebral angiography and TCD were normal. In 6 arterial lesions followed serially with TCD a stenotic pattern resolved within 4 and 6 months in 3 cases and remained in the stenotic range at 12 months in 1 case, whereas an occlusive pattern persisted at 6 and 18 months in the other 2 cases. In conclusion, TCD may be useful to detect and follow up cerebral vasculitis due to chronic cysticercotic arachnoiditis.

Adolescent↗
PubMedDate not supplied

Influence of previous housing history on the toxicity of amphetamine in aggregate mice.

The lethality of d-amphetamine was studied in isolated and aggregated mice with and without previous habituation to the physical or to the physical and social environment of chronically aggregated social condition under which the toxic effects of d-amphetamine were tested. In animals without previous habituation to such environments, d-amphetamine's toxicity was greatly enhanced by social aggregation, as reported by several authors in the literature. It was found that mortality in the dose range from 5 to 90 mg/kg is mainly determined by the stimulation due to aggregation. Above 90 mg/kg, the mortalities in single and aggregated mice vary in parallel. Up from this dose, lethality is independent of the external stimulation. Previous experience with house sharing in aggregated conditions reduces aggregation mortality in proportion to the duration of the previous house sharing period.

Adaptation, Psychological↗