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Biomedical subjects

J Versieck

Publications and source records attributed to J Versieck.

68 records · Page 4Linked to original sources

Vanadium determination at the ultra-trace level in biological reference materials and serum by radiochemical neutron activation analysis.

In order to help resolve present inconsistencies of two orders of magnitude or more in reported levels of vanadium in human serum and blood, a totally postirradiation radiochemical neutron activation analysis (NAA) method was further developed and applied to some pertinent nanogram and subnanogram reference materials. In particular, the second generation human serum reference material of Versieck was found to contain a value of 0.67 +/- 0.05 ng/g dry wt., corresponding to 0.061 +/- 0.005 /4/ ng/mL original fresh serum. Results are also reported for some other appropriate CRMs. Additionally, a small-scale study in 10 normal subjects (5 m, 5 f) revealed levels similar to those in the serum reference material and in agreement with the lowest data reported in the literature. Discussion of pitfalls of vanadium determination and the use of reference materials is included.

Adult↗

Determination of trace elements in human serum by inductively coupled plasma-mass spectrometry. Comparison with nuclear analytical techniques.

The determination of trace and ultratrace elements in human serum by ICP-MS is described. The accuracy of the method is tested using a "second generation" human serum reference material. Elements determined include Fe, Co, Cu, Zn, Br, Rb, Sr, Mo, and Cs. The method is compared to nuclear analytical methods (NAA, PIXE). Perspectives for the future are also discussed.

Evaluation Studies as Topic↗

Determination of mercury in human serum and packed blood cells by neutron activation analysis.

A method is described for the determination of mercury in human blood serum and packed blood cells employing neutron activation analysis. Great attention was devoted to the collection and manipulation of the samples. The accuracy and precision of the method were tested by analyzing biological reference materials and by comparing the concentrations measured in a number of serum samples to those obtained by another, independent technique (cold vapor atomic absorption spectrometry) in the same samples. The article reports the levels measured in blood serum and packed blood cells samples from 15 adult volunteers, as well as the figures determined in a "second-generation" biological reference material (freeze-dried human serum), prepared and conditioned at the University of Ghent.

Adult↗

Multifocal fatty infiltration of the liver; an aspecific presentation form of hepatitis C infection.

We present the case report of a 60 year old man with multiple focal echogenic lesions on ultrasound. While CT and MRI suggested the diagnosis of focal fatty infiltration of the liver, histology and serology showed a chronic hepatitis C infection. This is to our knowledge the first case of a patient with hepatitis C infection in whom focal steatosis could be seen on different imaging techniques.

Biopsy, Needle↗