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Biomedical subjects

J Vaysse

Publications and source records attributed to J Vaysse.

At least 37 records · Page 2Linked to original sources
PubMed1988

Effect of diosmin upon red blood cell deformability and osmotic fragility. Relationship with lipid content.

Rats were treated by ingesting forcibly 2 ml of a suspension of four different doses (100, 200, 300 and 400 mg/kg) of diosmin in carboxymethylcellulose (CMC) and were killed immediately or after 3 or 6 hours of fasting. Animals treated by CMC only in a similar way (gavage) exhibited a fall in red blood cell (RBC) membrane cholesterol and an increase in RBC rigidity at the third hour while osmotic fragility remained stable. Diosmin treatment opposed the rise in RBC rigidity evoked by the gavage and induced a dose-dependent decrease of the RBC membrane cholesterol over phospholipid ratio.

Animals↗
PubMed1987

Osmotic properties of human erythrocytes treated by phospholipase A2 from bee venom.

During treatment of human red cells with phospholipase A2 from bee venom, a linear increase of the MCV and of the osmotic fragility occurs in parallel with the cleavage of the accessible phospholipids. However, even after maximal hydrolysis, i.e. degradation of up to 65% of the phosphatidylcholines and up to 6% of the phosphatidyl-ethanolamines, almost no haemolysis is observed and the median corpuscular fragility is only 7% higher than that of control cells incubated without enzyme. Addition of albumin to the medium results in an important rise of the susceptibility to hypotonic saline solutions. Osmotic fragility curves obtained with red cells submitted to mild phospholipase action show evidence of subpopulations of cells with various sensitivities to osmotic lysis. This phenomenon can be partly explained by the heterogeneity of the cleavage intensity among the cell population. This hypothesis is supported by the studies of the lipid composition of phospholipase treated red cells fractionated according to their sensitivity to hypotonic lysis or to their size.

Bee Venoms↗
PubMed1986

Properties of rabbit erythrocytes treated with phospholipase A2 from bee venom.

In isotonic saline-buffered conditions, phospholipase A2 from bee venom cleaves up to 65% of the phosphatidylcholine of the rabbit RBC membrane without causing significant hemolysis; however, the volume and the osmotic fragility of the treated RBC is modified. The osmotic behaviour of PLA-treated RBC after reincubation in autologous plasma suggests an heterogeneity in the enzymatic attack among the RBC population. In vivo RBC survival is strongly impaired by PLA treatment.

Animals↗
PubMed1986

Adhesion and erythrophagocytosis of human senescent erythrocytes by autologous monocytes and their inhibition by beta-galactosyl derivatives.

Senescent human erythrocytes (RBC) are able to adhere to and be phagocytized by autologous monocytes in vitro to a greater extent than are young RBC. This adhesion and erythrophagocytosis of senescent RBC is inhibited by D-galactose, N-acetyl-D-galactosamine, their corresponding derivatives of bovine serum albumin, and lactose. On the other hand, D-glucose, D-mannose, L-fucose, N-acetyl-D-glucosamine, and their corresponding derivatives of bovine serum albumin are noninhibiting. The glycopeptides released by tryptic digestion of senescent RBC and purified on immobilized peanut agglutinin are the most effective inhibitors of both RBC adhesion and phagocytosis by autologous monocytes obtained from peripheral blood.

Cell Adhesion↗
PubMed1986

Plasma and erythrocyte lipid composition in normal pregnancy.

Variations of the plasma and erythrocyte lipid composition were studied in 110 clinically normal pregnant women at different gestational ages; a longitudinal study, carried out in 10 of these women, confirms the results of the cross-sectional study. The main changes observed in the plasma are a rise of the levels of triglycerides, phosphatidyl-cholines and to a lower extent of sphingomyelins; these increases are significantly correlated with the gestational age. The RBC lipid composition is faintly modified throughout pregnancy; the most important changes are observed close to term: after 35 weeks of gestation, the concentration of sphingomyelins, phosphatidyl-cholines and phosphatidyl-ethanolamines are higher and that of the cholesterol/phospholipids is lower than at the beginning of pregnancy. Modifications of some erythrocyte physical properties occurring in the course of gestation cannot mainly be attributed to variations of the membrane lipid composition.

Adult↗
PubMed1985

Sweat collection from athletes.

The difficulty in taking sweat during heavy physical exercise has drawn the authors into testing a technique of sampling generally used in paediatrics. The fact that the results, which have been dealt with statistically, should coincide with the physiological facts already published allows us to consider a use of the technique in order to investigate the physiological mechanisms in action during sweating under different metabolic conditions.

Adult↗
PubMed1983

Estimation of swimmers' physical condition by a swimming recovery test.

In this article, the authors propose an original analysis of the cardiac frequency after training. The study of rapid diminution (alactic oxygen debt) and of plateau (lactic debt in oxygen) make possible adjustment of the training. The variations observed in young swimmers during their sporting season and note a tangible improvement of the two components for recovery.

Child↗
PubMed1981

Trisalbuminemia.

Explore the source record for details and available documents.

Adult↗
PubMed1980

[Abnormal serum iron carrier in a case of malignant histiocytosis (author's transl)].

A patient with malignant histiocytosis had an iron plasmatic concentration above 600 gamma/100 ml. An abnormal iron-binding protein incompletely saturated is demonstrated in the plasma. This protein has an electrophoretic migration near the alpha 2 globulins and no immunological reactions with antitransferrin and antiferritin antibodies. Its affinity for iron is less and its molecular weight is greater than the one of transferrin. Such a protein has not already been described in the plasma and its presence should be related to the malignant disease.

Alpha-Globulins↗
PubMed1980

[Bitachycardia].

One or several episodes of bitachycardia (a simultaneous ventricular tachycardia and atrial tachycardia or fibrillation) were observed in 13 patients. An oesophageal or right atrial endocavitary recording is usually necessary to show the atrioventricular dissociation: even then the diagnosis may be difficult in cases of isorhythmic dissociation or when the ventricular tachycardia is irregular. In 5 cases the double tachycardia appeared to be coincidental. In 7 patients the ventricular tachycardia seemed to be dependant on the atrial tachycardia and could be initiated by a simple spontaneous atrial extrasystole in 3 cases. In one patient the ventricular tachycardia, after a phase of retrograde conduction to the atria, initiated the atrial arrhythmia. The therapeutic indications depend in part on the eventual relationship between the two arrhythmias.

Aged↗