Search PubMed⌕ Search

Biomedical subjects

J Varon

Publications and source records attributed to J Varon.

At least 19 recordsLinked to original sources
PubMed2001

Management of the obese critically ill patient.

The management of the morbidly obese critically ill patient is a challenging and formidable task. A better understanding of the pathophysiologic changes that occur with obesity and the complications unique to this group of patients may improve their outcome.

Cardiovascular Physiological Phenomena↗
PubMed2000

Hyponatremia, cerebral edema, and noncardiogenic pulmonary edema in marathon runners.

BACKGROUND: Noncardiogenic pulmonary edema is often associated with increased intracranial pressure and can be the initial manifestation of hyponatremic encephalopathy. Marathon runners tend to develop conditions that lead to hyponatremia. OBJECTIVE: To describe the development and treatment of noncardiogenic pulmonary edema in marathon runners that was associated with hyponatremic encephalopathy. DESIGN: Case series. SETTING: One university hospital and two community hospitals. PATIENTS: Seven healthy marathon runners who had a history of nonsteroidal anti-inflammatory drug use. The runners collapsed after competing in a marathon and were hospitalized with pulmonary edema. MEASUREMENTS: Plasma sodium levels, chest radiograph, electrocardiogram, cardiac enzyme levels, and magnetic resonance imaging or computed tomographic scans of the brain. RESULTS: Patients had nausea, emesis, and obtundation. The mean (+/-SD) plasma sodium level was 121 +/- 3 mmol/L, and oxygen saturation was less than 70%. Electrocardiograms and echocardiograms were normal. Chest radiographs showed pulmonary edema with a normal heart. Creatine phosphokinase-MB bands, troponin levels, and pulmonary wedge pressure were not elevated. Scanning of the brain showed cerebral edema. All patients were intubated and mechanically ventilated. Treatment with intravenous NaCl, 514 mmol/L, increased plasma sodium levels by 10 mmol/L in 12 hours. Pulmonary and cerebral edema resolved as the sodium level increased. One patient had unsuspected hyponatremic encephalopathy and died of cardiopulmonary arrest caused by brainstem herniation. All six treated patients recovered and were well after 1 year of follow-up. CONCLUSIONS: In healthy marathon runners, noncardiogenic pulmonary edema can be associated with hyponatremic encephalopathy. The condition may be fatal if undiagnosed and can be successfully treated with hypertonic NaCl.

Adult↗
PubMed2000

Critical care transport.

The transport environment presents challenges not faced in the hospital arena. Both ground and air ambulance transport vehicles are hampered by space limitations, lack of universally available power, and physical forces of no importance in the stationary hospital environment. EMS personnel are typically used in ground and air transports augmented by hospital practitioners on request. The capabilities of EMS workers is limited, and their limits must be considered when any patient transport is conducted. Prior planning and understanding the limitations of the transport arena are the keys to successful transport. The future will likely see improvements in technology and integration of hospital delivery systems and patient management systems, expanding our ability to provide critical care outside the traditional ICU environment.

Aircraft↗
PubMed2000

The diagnosis and management of hypertensive crises.

Severe hypertension is a common clinical problem in the United States, encountered in various clinical settings. Although various terms have been applied to severe hypertension, such as hypertensive crises, emergencies, or urgencies, they are all characterized by acute elevations in BP that may be associated with end-organ damage (hypertensive crisis). The immediate reduction of BP is only required in patients with acute end-organ damage. Hypertension associated with cerebral infarction or intracerebral hemorrhage only rarely requires treatment. While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances. Furthermore, the short-acting calcium channel blocker nifedipine is associated with significant morbidity and should be avoided. Today, a wide range of pharmacologic alternatives are available to the practitioner to control severe hypertension. This article reviews some of the current concepts and common misconceptions in the management of patients with acutely elevated BP.

Aortic Dissection↗
PubMed1999

Automatic external defibrillators: lessons from the past, present and future.

Coronary artery disease remains the leading cause of death in the United States and most developed countries. Many of the victims die from sudden cardiac arrests, resulting from dysrhythmias-most commonly ventricular fibrillation. Since most cardiac arrests occur outside the hospital, implementing emergency services in the field will have a great impact on survival. With the development of the modern automatic external defibrillator (AED), early recognition and correction of these dysrhythmias by lay rescuers can significantly improve outcome from sudden death. This paper reviews the past, present and future development and applications of AEDs.

Electric Countershock↗
PubMed1999

Physicians' own preferences to the limitation and withdrawal of life-sustaining therapy.

While limiting and forgoing therapy at the end of life is now accepted on medical, ethical, moral and legal grounds, many Americans continue to die with heroic measures being taken to prevent their death. Recent studies have demonstrated that physicians frequently attend to their patients without knowledge of their preferences with regards to end-of-life issues. It is postulated that a physician's personal preferences with regard to the limitation and withdrawal of life support and active euthanasia would effect the discussion they had with their patients. The purpose of this study was to analyze end-of-life preferences of a diverse group of practicing physicians. The participants were active attending physicians at a community hospital, a rural referral center, a large tertiary care referral academic complex, and a specialized tertiary care referral center all within the United States. A questionnaire was developed which was mailed to attending physicians at the four participating medical centers. The respondents provided basic demographic data, do-not-resuscitate (DNR) preferences under various clinical circumstances as well as responses to a number of case vignettes. Six hundred and forty physicians responded to the survey. The mean age of the respondents was 46 years; 72% were male. In the event of a cardiac arrest less than 20% of respondents would want to undergo cardiopulmonary resuscitation in the setting of chronic end stage organ failure; the positive response rate was 5% for metastatic cancer and 2% for Alzheimer's disease. If death was imminent, 87% of physicians indicated they would want treatment withdrawn. Similarly, 95% of respondents indicated that they would want treatment withdrawn should they be in a persistent vegetative state. Only 1% of respondents believed that health care providers should never remove or withhold life-sustaining therapy. Should they have advanced motor neuron disease, 38% of physicians indicated they would request that their life be ended. The majority of physicians surveyed volunteered that they would want life-sustaining measures to be limited at the end of their life. A significant number were in favor of active euthanasia. This study suggests that it is unlikely that physicians' personal beliefs in regards to end-of-life care result in the failure to discuss these issues with their patients.

Attitude of Health Personnel↗
PubMed1999

Critical care and the World Wide Web.

The Internet was created in 1969, when the Advanced Research Projects Agency of the United States Department of Defense fired up an experimental network consisting of only four computers. Over the past five years there has been an exponential explosion in the number of computers added to this network. It is estimated that Internet traffic doubles every 100 days with more than 100 million people worldwide now on-line. The Internet is so vast that practically every aspect of human interest is represented is some form or fashion. From recreation to applied science and technology, and from Critical Care Medicine case scenarios to digitized radiology images and pathology specimens, the Internet has become increasingly useful for critical care practitioners. To date, no resource is better equipped to assist critical care providers in many of their daily tasks. This article presents some of the historical developments of the Internet as well as common applications that are useful for critical care practitioners.

Critical Care↗