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Biomedical subjects

J Valeyre

Publications and source records attributed to J Valeyre.

33 records · Page 2Linked to original sources

Metastatic calcification in the thyroid gland demonstrated on bone scan in a patient with primary hyperparathyroidism.

Bone scanning agents are known to accumulate in extraskeletal sites. We report the case of a patient with primary hyperparathyroidism whose bone scan performed with [99mTc]HMDP revealed not only the classic pattern described in hyperparathyroidism, but also a striking visceral uptake in the lungs, heart, stomach, and thyroid gland. Metastatic calcification was found on histologic examination of the thyroid.

Aged↗

Assessment of divided renal function by renography. Validation in patients with separate urine collections from each kidney.

Divided renal function was measured by 99mTc-DTPA renography using a gamma camera and a computer-assisted program. In 14 patients with permanent bilateral ureterostomies (7) or temporary ureteric catheterization (7), split renal function was calculated by analysis of the initial phase of the kidney activity-time curve and measured simultaneously by conventional clearance techniques. A high correlation was found between individual clearances measured by computation and by the conventional procedure. The correlation coefficient between the results obtained by the two techniques was 0.94 (P less than 0.001). A high correlation was also shown to exist between the computed clearance and the renal uptake of mercury after administration of 197HgCl. It is concluded that 99mTc-DTPA is particularly useful for the measurement of divided renal function without the need for urine collection.

Humans↗