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Biomedical subjects

J V Reyniak

Publications and source records attributed to J V Reyniak.

34 records · Page 2Linked to original sources
PubMed1976

Dysfunctional uterine bleeding.

The etiology and pathogenesis of dysfunctional uterine bleeding are discussed. For both age groups, adolescents and perimenopausal women, gonadotropin-steroid patterns as well as endometrial changes are presented. Methods of evaluation and therapy are described, including curettage and judicious of estrogen-progestogen combinations. Finally, long-term follow-ups of these patients are presented, with plans for reevaluation as well as palliative treatment based on the bleeding patterns and gonadotropin levels.

Adolescent↗
PubMed1976

Conservative surgical management of tubal pregnancy.

In an attempt to maintain optimal fertility in the patient treated for midtubal pregnancy, an investigation of conservative surgical procedure was made. The technic developed utilizes tubal excision, reanastomosis, and a single hydrotubation with Dextran. Tubal patency was maintained without the use of stents that may damage the fimbria. The procedure is compared to other conservative technics and its advantages discused. Thus far 2 patients have undergone this excision and reanastomosis, and both patients successfully established intrauterine gestations within 2 months of returning to normal active coital frequency. Both were in the midtrimester of pregnancy at the time of this report.

Adult↗
PubMed1975

Endometrial dating correlated with progesterone levels.

The aim of this work was to document the validity and usefulness of progesterone determination instead of endometrial biopsies as evidence for ovulation within a menstrual cycle. The presence of progesterone in amounts greater than 2 ng/ml of plasma was always associated with a secretory endometrium, ie, the endometrium was matured beyond cycle day 14 as diagnosed by classical histologic dating. The remarkable simplicity of quantitating luteal phase progesterone levels by this radioimmunoassay warrants their extended use for evaluating the physiology and the pathology of the corpus luteum.

Biopsy↗
PubMed1975

Endometrial regeneration after voluntary abortion.

Endometrial biopsies were obtained on postabortal days 1 to 36 in 42 women without contraception, in 28 women using oral contraceptives, and in 12 women with intrauterine devices. Tissue samples were examined for day-to-day sequential changes, specifically: a)regenerative, repair, proliferative and secretory activity, b)involution of pregnancy changes, c)inflammation. In the absence of contraception, the endometrium promptly regenerated. The earliest evidence of ovulation was on day 9. One-third of the women ovulated before the first period. Incomplete placental and decidual involution was seen in 45% of patients, but its frequency progressively decreased toward the end of observation. Inflammation seen in 26% was limited to the retained decidua and was, therefore, thought to be a reactive rather than an infectious phenomenon. In women taking oral contraceptives, initial regeneration was also prompt. "On pill" changes resembled the nonpostabortal picture except for a few cases of cystic glandular dilation, or Arias-Stella-like phenomena. Retained decidua and inflammation were more frequent (75% and 68%) than in the noncontraceptive group, and the diminishing trend was not observed. In the intrauterine device group, inflammation was more frequent (83%) than in the other two groups and was not limited to the decidua.

Abortion, Induced↗