Search PubMed⌕ Search

Biomedical subjects

J Urban

Publications and source records attributed to J Urban.

At least 163 records · Page 9Linked to original sources
PubMed1978

[The Netherton syndrome with alopecia and prolinuria].

A six month old boy under observation for over two years developed an ichthyosiform erythroderma with alopecia, which was diagnosed as Netherton syndrome. Histologic examination of the hair roots showed trichorrhexis invaginata (bamboo hair), trichorrhexis invaginata torta and pili torti. Prolinuria was detected. Local therapy with corticosteroids was without any effect. These symptoms can be attributed to aminoaciduria (prolinuria).

Alopecia↗
PubMed1977

Cell division and sister chromatid exchanges in 45,X/46,Xi(Xq) mosaicism.

The kinetics of cell division and sister chromatid exchanges were studied in PHA-stimulated short-term cultivations of peripheral blood by means of the BUDR/FPG technique in controls and in five patients with 45,X/46,X,i(Xq) mosaicism. No significant difference in the length of the cell cycle were observed between 45,X/46,X,i(Xq) and control 46,XX cells. The number of SCE on late i(Xq) was only nonsignificantly elevated (0.6 per i(Xq) against the value expected on the basis of its relative length.

Cell Cycle↗
PubMed1977

[Weight parameters of various internal organs].

The weight of some organs [brain, heart, lungs, kidneys, liver] was ascertained in a group of 1,598 persons who died a violent death, and a comparison was made with values obtained in a group of persons who died of cardiac insufficiency. The figures found were correlated according to sex with age, obesity, lipomatosis, physical size, the presence and stage of atherosclerosis. --Within the violent death group, a correlation was also made between a subgroup with minimal or no presence of atherosclerosis and one with ascertained atherosclerosis. The average weight of the brain was found to be 1419.6 g in men, 1266 g in women; the heart--394.7 or 343 g; kidney--149.0 g or 124.1 g; lungs 1280.0 or 973.4 g; liver--1770.9 g or 1522.0 g.

Adult↗
PubMed1976

The kinetics in vivo of the synthesis of albumin-like protein and albumin in rats.

The incorporation of radioactivity into total protein, albumin-like protein and albumin in liver and into total protein and albumin in blood plasma, was studied for a time period of 2 h after intraportal injection of L-[1-14C]leucine. 1. In the liver, radioactivity began to increase in albumin-like protein before 2.5 min and in albumin at about 10 min after injection. In the plasma, radioactive albumin appeared at about 15 min. No albumin-like protein could be detected in the plasma. 2. Maximum radioactivity was reached first in albumin-like protein, then in hepatic albumin and finally in albumin in the blood-stream. The maximum specific radioactivity of albumin-like protein was 15 times higher than that of extravascular hepatic albumin which, in turn, was 6 times higher than that of plasma albumin. 3. The increase of radioactivity in albumin in the blood corresponded almost quantitatively to the decrease of radioactivity in albumin-like protein. 4. It is concluded that the albumin-like protein is the precursor of albumin in vivo. It is converted into albumin 5-6 min before the appearance of newly synthesized albumin in the blood-stream.

Animals↗