[Blood volume and urinary sodium, potassium and uric acid in cirrhosis. Evidence of the hypersensitivity of the nephron to aldosterone].
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Biomedical subjects
J Unger
Publications and source records attributed to J Unger.
Building a classification system that works.
The process one nursing department used to develop, test, implement, and monitor a definitive patient classification system that accurately predicts needed nursing staff and correlates with department budget is described. The author demonstrates that staff nurses with ordinary skills and experience, using limited resources of time and money, can build a valid, reliable, workable system amenable to computerization and future use in costing out nursing care on an individual patient or diagnosis related group (DRG) basis.
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Hyponatremia in the syndrome of inappropriate secretion of antidiuretic hormone. Rapid correction with urea, sodium chloride, and water restriction therapy.
In the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), rapid elevation of serum sodium concentration may be imperative to correct neurological symptoms. Seven patients with hyponatremia secondary to SIADH were treated by oral intake of two to three doses of 30 g of urea over 24 hours or infusion of 80 g of urea as a 30% solution of over six hours, water restriction (500 mL/24 hr), and sodium supplements (120 to 360 mmole/24 hr). Serum sodium concentration increased from 117 +/- 2 to 126 +/- 1.4 mmole/L (mean +/- SEM) after eight hours, to 130 +/- 1.3 mmole/L after 12 hours, and to 134.5 +/- 1.2 mmole/L after 24 hours. The normalization of serum sodium was secondary to osmotic diuresis and to sodium retention induced by urea. Use of urea should be considered when symptomatic hyponatremia in SIADH must be quickly corrected.
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