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Biomedical subjects

J Ulrich

Publications and source records attributed to J Ulrich.

At least 163 records · Page 9Linked to original sources
PubMed1978

Subacute necrotizing encephalopathy (Leigh) in an adult.

The case of a 31-year-old man who died after a 4 month illness of adult subacute necrotizing encephalomyelopathy (Leigh) is reported. The disease presented with visual disturbances and the principal symptoms were ptosis, a conjugate ophthalmoparesis and a slight tremor of the hands. The case was misdiagnosed as probable multiple sclerosis. Neuropathology disclosed characteristic symmetrical necrotizing lesions, mainly localized in the brain stem. The similarity of the lesions with Wernicke's disease is pointed out. Possible etiological and pathogenetic factors are discussed.

Adult↗
PubMed1977

Seitelberger's connatal form of Pelizaeus-Merzbacher Disease. Case report, clinical, pathological and biochemical findings.

A case of Seitelberger's connatal form of Pelizaeus-Merzbacher disease is reported. He lived to the age of 13 and was able to recognize persons. Both is unusual in this disease. Some of the few myelin sheaths had two different periodicities (150 and 90 A). Intranuclear inclusions similar to Hirano's cytoplasmic eosinophilic rodlets were observed. The findings of connatal form of Pelizaeus-Merzbacher disease are compared with those of dysmyelinating mice (Jimpy and Quacking) and of manipulated myelinating tissue cultures. The possibility is considered, that the alterations in these dysmyelinating human and animal conditions are caused by extraneural circulating factors.

Adolescent↗
PubMed1977

[Clinic and pathogenesis of Morton's disease (author's transl)].

From experience with 58 own cases the authors found that Morton's metatarsalgia due to a sclerosing neuroma of the plantar digital nerve is very often not recognised for many years. As this painfull affection easily can be cured, the clinical symptoms and histological findings, the diagnostic steps and treatment are described and the etiology discussed. For the excision of the plantar digital neuroma, situated generally between 3rd and 4th metatarsal head, the dorsal web-splitting approach is preferred because of better scars and immediate weigt-bearing. The operation is performed on outdoor patients. There were no complications. The results of 35 operations two or more years back show immediate and complete relief of pain in 31 cases and significant but incomplete relief in 4 cases.

Adult↗
PubMed1977

Scapulo-peroneal muscular atrophy. Full autopsy report. Unusual findings in the anterior horn of the spinal cord. Lipid storage in muscle.

Morphological findings of 3 cases of Kaeser's scapulo-peroneal muscular atrophy are described. 1 of them is the first complete autopsy report on this disease. While the number of motor neurons in the spinal cord was grossly normal, the neuropil of the anterior horn exhibited axonal swellings, accumulations of possibly pathological lipofuscin and intra-axonal corpora amylacea. In the muscles, changes were partly those of neurogenic atrophy, partly of a primary myopathy. There was also an accumulation of neutral fat in the muscle fibres, mainly of those of type I.

Aged↗
PubMed1977

Analysis of sudden deaths in a district of Bohemia in the period 1971--1973.

A clinico-pathologico-anatomical analysis of 150 cases of sudden death in a district of Bohemia in the period 1971--1973 revealed coronary atherosclerosis as the most frequent cause of sudden death(87.3%); stenosing coronary atherosclerosis without postmortally detectable myocardial necrosis participated by 71.7% in the coronary group. Men, especially in younger age groups, were more frequent victims than women. Within one-hour duration of the terminal episode, 57.3% of the deaths occurred; 45.3% of the decreased succumbed to sudden death at their homes. With advancing age, severe findings in the coronary vascular bed and in the myocardium became more frequent. One half of the victims of sudden death in the coronary group had histories of ischaemic heart disease; 37 suddenly deceased persons (28.2%) had experienced myocardial infarction. In another 25 victims of sudden death scars after formerly asymptomatic myocardial infarcts were found.

Adolescent↗
PubMed1975

Kuru-plaques in creutzfeldt-jakob disease.

A case of Creutzfeldt-Jakob disease of cerebellar type is reported. In this case the cerebellar cortex exhibited classical Kuru-plaques. From a comparison of this finding with 50 cerebella from senile patients and patients with cerebellar atrophies it is concluded that the Kuru-plaque is specific for Creutzfeldt-Jakob disease, possible even for its cerebellar variant.

Aged↗