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Biomedical subjects

J Trotoux

Publications and source records attributed to J Trotoux.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Monitoring of thyroid function in patients treated for cancer of the upper respiratory and digestive tract].

A study was carried out at Hôpital Boucicaut to determine the incidence of iatrogenic biological thyroid dysfunction in patients treated for cancer of the upper digestive and respiratory tracts, and to define the risk profile (tumor localisations, practical therapeutical procedures). Two studies were conducted: a prospective on including 18 patients and a retrospective one including 58 patients. Only partial results are currently available. They permit emphasizing the frequency of biological thyroid dysfunction associated both with combination surgical and radiotherapeutical regimens and radiotherapy or radiotherapy alone for the treatment of lesions of the piriform sinus, although they fail to provide conclusive evidence regarding the real frequency of this type pathology or the time of its occurrence.

Carcinoma, Squamous Cell↗
PubMed1989

[Evaluation of cochlear function in otospongiosis. Preliminary study].

One of the major therapeutical problems encountered in the natural history of otospongiosis are lesions affecting Corti's organ. We obtained audiometric measurements, including pure-tone and speech audiograms, tympanograms, and spontaneous and provoked otoemission determinations in 26 patients (40 ears), who benefited from total platinectomy and collumellar effect recuperation by means of temporal aponeurosis interposition and piston-cupping. Results show that the piston-cup procedure does not appear to modify the transfer function of the middle ear. On the other hand, even at a stage when pure-tone and speech audiograms show little alteration, there seems to be some lesion of the external ciliated cells of Corti'organ.

Adult↗
PubMed1989

[Lymph node failure in epithelioma of the glottic floor treated by partial laryngeal surgery. Apropos of 432 patients].

The authors assessed ganglionic failure in a series of 432 cases of N0 M0 epidermoid carcinomas of the glottic floor following partial laryngeal surgery. The overall of ganglionic failure was 7.8%. This rate of failure is related to 64.7% death rate, i.e. 5.1% of the 432 patients under study. This retrospective study differentiates between primary ganglionic failure and secondary ganglionic failure. Primary ganglionic failure is the first local/regional carcinologic event to develop after treatment of any glottic lesion. Secondary ganglionic failure is related to isolated local failures. The percentage of primary ganglionic failure was 5.1%. It was responsible for deaths occurring in 54.5% of cases. The percentage of secondary ganglionic failure was 2.7% and it was responsible for deaths occurring in 83.3% of cases. Factors promoting ganglionic failure (real tumor extension, tumor infiltration, altered laryngeal mobility, local control and efficacy of retakes of local failures) are discussed. The importance of prophylactic surgical procedures guarding from ganglionic failure, such as the ipsilateral jugular-carotid and recurrent nerve approaches is emphasized. Although such procedures can be of aid in cases of T2 or T3 N0 M0 epitheliomas of the glottic floor, they present no alternative in the course of retake operations of local failures.

Adult↗
PubMed1989

[An approach to tumors of the face by degloving. An elegant treatment of inverted papillomas and various sinus cancers. Values. Limitations and extension].

Degloving constitutes a hidden route of access to the middle third of the face. It combines a bilateral sublabial incision with a rhinoplastic approach, whereby all the soft tissues of the face can be undermined subperiosteally, leaving no external scar. This method offers an extended bilateral route of access to lesions of the nasal cavities and ethmoid/sphenoid/maxillary sinuses, deep to the clivus. Its exposing features at least compare with conventional technics, including bone resection or the creation of a valve. This procedure may be associated with other neurosurgical approaches in the treatment of extended lesions of the basis of the skull. Its use is particularly recommended in the treatment of inverted papillomas, although it applies as well to malignant tumors of the sinuses under certain conditions. We present here a review of our experience.

Aged↗
PubMed1989

[Prefabricated free transplants. Experimentation].

The principle of prefabricated transplants consists in the manufacturing of compound transplants complete with a vascular pedicle containing an artery, a vein, a muscle and its nerve, some cell tissue, bone tissue, cartilage, periosteum and innerved skin. This transplant is constructed and modeled in accordance with its intended use, around the preselected vascular pedicle, whence the term prefabricated. Neovascularization revascularizes these different structures. The free transplants together with their vasculonervous pedicles are excised five weeks after manufacture and then transplanted to the recipient site. Experimentally, we grafted 15 free prefabricated transplants in Wistar rats. One failure was observed due to thrombosis of the anastomoses. Experimental data from macroscopic, arteriographic, microangiographic, and histological examinations, with injection of a staining material, show that neovascularization develops at the level of the transplant. The emphasis is on creating free transplants selectively using various tissues and selected vascular pedicles. These transplants constitute a useful prospective alternative for very elaborate reconstructive surgery.

Animals↗
PubMed1989

[The Chinese flap in reconstructing the posterior pharyngolaryngeal wall, mouth cavity and in reoperation after failure of pedicled digestive transfer].

The Chinese flap has already been recommended in the context of circular pharyngolaryngectomy. The authors studied its vascularization from an anatomy-focusing project carried out on 40 dissection cases. They broaden the applications of this material to posterior reconstructive pharyngectomy, for which they specify the methods and routes of access. Other applications are proposed: this flap may represent an alternative for reconstitution of the oral cavity, or even as a second-intent surgical procedure where other technics have failed.

Adult↗
PubMed1989

[Mucormycosis of the face associated with aspergillosis in the diabetic patient. Diagnostic and therapeutic considerations].

Facial mucormycosis is a rare fungal infection which spreads rapidly and has a severe prognosis. It mainly affects insulin-dependent diabetics and immunodeficient subjects. We report about a case of mucormycosis of the facial structures in a diabetic patient, and lay particular stress on the diagnosis difficulties, on treatment and on evolution, which led to healing, leaving an extensive bony sequestrum which preserved the contents of the orbits.

Amphotericin B↗
PubMed1986

[Laryngeal nerves. A histomorphometric and cartographic study].

Major difficulties in laryngeal reconstruction are due to laryngeal nerves. A study was conducted of 100 larynges from fresh subjects after vascular injection. Vascularization of superior laryngeal nerves is derived essentially from superior laryngeal and ascending pharyngeal arteries. Inferior laryngeal nerves obtain their vascular supply from inferior thyroid and main carotid arteries. Histomorphometric study of laryngeal nerves used semi-automatic techniques: microscope, numerical table, computer, printer. The number of fibers per nerve varied between 511 and 2.244, the number of nerve fasculi between 3 and 14, and the diameter of myelinated fibers between 2 and 12 micron. Fibers of left inferior laryngeal nerve had a mean diameter (8.9 to 10.2) greater than those of right inferior laryngeal nerve (5.1 to 5.2 micron). Nerve tissue represented 60% to 66% of total. The left recurrent was longer than right nerve but had larger fibers providing more rapid conduction. Cartography of laryngeal nerves from 2 mm serial sections confirmed their plexis structure, this study providing new and objective precisions on laryngeal nerve structure.

Histological Techniques↗
PubMed1986

[Vascularization of the larynx. Update of classical anatomic data from an anatomical study of 100 subjects].

The study was conducted after arterial and venous neoprene latex injection to 100 fresh subjects. Three laryngeal arteries are constant: superior, inferior and posterior. The superior laryngeal artery is of variable origin: in 84% of cases it arises from superior thyroid artery. Anastomoses between the three laryngeal pedicles and the muscle territories supplied by the arteries are described. Vascularization of cartilages is according to a precise plan and cricothyroid and cricoarytenoid joints are the site of constant arterial anatomoses. Origin of superior laryngeal artery fluctuates due to sliding phenomena. The notion of a neurovascular pedicle is fundamental: it is formed by the neural crest derivation and the corresponding artery, that is to say the artery and nerve of a branchial arch. This is to be compared with the notion of pure musculocutaneous and glandular pedicles. The larynx is a junctional zone between 4th and 6th branchial arches and is integrated with the cervicocephalic system of aortic arches.

Arteries↗