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Biomedical subjects

J Tomanová

Publications and source records attributed to J Tomanová.

14 recordsLinked to original sources
PubMed1986

Haptoglobin type in connection with mean age at first breast cancer signs?

In breast cancer patients divided into groups according to haptoglobin (Hp) type (519 patients), blood group (ABO) (433 patients) or Rh factor (358 patients) the mean age at first disease manifestation was calculated. The results indicate that in Hp 1 bearers breast cancer appears at significantly lower age (49 years) as compared to Hp type 2-1 (53.3 years) or Hp 2 (53 years). In blood groups the mean age at first cancer signs raises from 48 years in the AB group to 53.1 years in the A group, only the difference between A and AB being significant. However, these preliminary results require confirmation in larger patient series.

ABO Blood-Group System↗
PubMed1982

Longitudinal follow-up circulating immune complexes of the serum in patients with breast cancer.

The values of circulating immune complexes (CIC) in patients with breast cancer were followed for one year at 4-month intervals by means of the "PEGIKEM" test. From the total of 67 patients, 37 were treated surgically and a significant decrease in mean values of CIC occurred 8 months after the operation. 30 patients with a more advanced stage of the disease treated with radiotherapy and chemotherapy showed a decrease in mean CIC values already after 4 months but later on the CIC values increased again. No significant differences in the mean CIC values prior to treatment between individual clinical stages were found, only a certain tendency towards a more frequent occurrence of higher CIC values in more advanced stages was noted. Nor were the findings in lymph nodes reflected in the mean CIC values prior to treatment. Comparison of CIC values prior to treatment and the results of 2-hour blood sedimentation, revealed conformity in only 40% of the patients. In the other cases higher values of blood sedimentation were more frequent. The study of prognostic value of CIC after 3 and 5 years follow-up is in progress.

Antigen-Antibody Complex↗
PubMed1981

Alterations of plasma levels in malignant lymphoma.

Fibrinogen levels were investigated in the plasma of a group of patients with malignant lymphoma consisting of M. Hodgkin's and non-Hodgkin's lymphoma, and were found to be significantly higher in an acute onset of the disease and in relapses, than in a control group of healthy blood donors. In the terminal stages, fibrinogen levels in the plasma were observed to decline towards the upper normal limits. Plasma fibrinogen levels are considered to be a good indicator of the activity of the disease.

Adolescent↗