[Observations on the diatom question].
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Biomedical subjects
Publications and source records attributed to J Timperman.
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A suicidal poisoning committed by a sixty-five year old woman, who swallowed a bottle of Agroxyl, containing an aqueous 250 g/L solution of the sodium- and potassium salt of 2-methyl-4-chlorophenoxyacetic acid [MCPA], together with lethal amounts of a parathion formulation, is described. The case history, the postmortem examination and the concentrations of parathion and MCPA in the different viscera, are reported in detail. Parathion determination was performed by means of a routine method, previously developed in our laboratory. The MCPA quantification was achieved using a thoroughly evaluated EC- GLC micro-analytical procedure, which is discussed completely. Identity was confirmed by GC-MS. Intake of lethal parathion quantities caused the woman's death with five minutes. This case however is worth reporting, since we had the unique opportunity to establish the early distribution of MCPA through the body, during the short period of survival.
The authors relate a suicidal poisoning by nitrites. Post mortem findings are reported as well as a method for the quantitative assessment of NO2- in blood, urine, gastric and intestinal contents, kidney and liver. The concentration values obtained are correlated with the methemoglobin figures which indeed are lethal. The highest concentrations of NO2- are found in the small intestine where the nitrites seem to resist chemical decomposition owing to the reducing properties of the bacterial flora.
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