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Biomedical subjects

J Thomasson

Publications and source records attributed to J Thomasson.

At least 217 records · Page 12Linked to original sources

Detection of right-to-left shunt with radionuclide angiocardiography in refractory hypoxemia.

A significant right-to-left shunt at the atrial level was diagnosed by radionuclide angiocardiographic examination in a patient with hypoxemia whose perfusion scan showed no pulmonary uptake. The shunt occurred through a patent foramen ovale due to increased right ventricular afterload, subsequently confirmed at autopsy. It is concluded that radionuclide angiocardiography with technetium 99m macroaggregated albumin (99mTc MAA), followed immediately by a perfusion lung scan, may have a place in the evaluation of patients with refractory hypoxemia, since pulmonary embolism and/or right-to-left shunting are two of several causes of hypoxemia in the absence of congenital heart disease. A review of the literature on different pathophysiologic factors is presented and some therapeutic implications, specifically the adverse effect of PEEP in such situations, are discussed.

Adult↗

Computed tomography and ultrasound appearance of liver disease in secondary syphilis.

Liver disease occurring as a manifestation of secondary syphilis is unusual, and this association is not readily recognized or considered in the differential diagnosis of obscure hepatic disease, thereby causing delay in treatment. We describe a case of liver involvement in secondary syphilis with computed-tomography and ultrasound findings. This entity should be considered in patients with hepatomegaly coexisting with the clinical stigmata of secondary syphilis, as treatment with penicillin results in rapid improvement in both the clinical and biochemical findings.

Adult↗