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Biomedical subjects

J Templeton

Publications and source records attributed to J Templeton.

51 records · Page 3Linked to original sources
PubMed1980

Hip fractures in patients with Parkinson's disease.

A series of patients with Parkinson's disease and hip disease over a period of 10 years was reviewed at 3 McGill University hospitals. There were 47 patients with 49 hip fractures. The mean age was 76 years. There were 27 subcapital fractures and 22 intertrochanteric fractures. The overall 6-month mortality was 47%. The mortality in the subcapital group was 60% and that in the intertrochanteric group 27%. The mortality in the patients with subcapital fractures treated with an endoprosthesis was 75%. The incidence of dislocation in the group treated with endoprosthesis was 37%, and all those patients died. The overall incidence of pressure sores was 49%. Internal fixation is recommended for treatment of hip fractures in patients with Parkinson's disease.

Aged↗
PubMed1977

Improved survival after coronary bypass surgery in patients with poor left ventricular function: role of intraaortic balloon counterpulsation.

The operative mortality rate of aortocoronary bypass surgery in 23 patients with poor left ventricular function (ejection fraction 0.30 or less) operated on in 1973-74 was 34.7 percent. The incidence rate of operative myocardial infarction was 30.4 percent. In an attempt to improve survival, intraaortic balloon counterpulsation was used therafter in 25 similar patients. Counterpulsation was instituted preoperatively and continued intra- and postoperatively for 2 to 5 days. Preoperative studies revealed an "unloading" effect of the left ventricle, with significant reductions of systolic arterial blood pressure, end-diastolic pulmonary arterial pressure and end-diastolic left ventricular volume and pressure. Metabolic improvement was demonstrated by the lesser production of myocardial lactate after pacing-induced tachycardia when the ventricle was balloon-assisted. Intraoperatively, blood flow through the vein graft was found to increase with counterpulsation. The rate of operative myocardial infarction was reduced to 4 percent and the mortality rate to 8 percent. In patients who have sustained a significant loss of functioning myocardium, the beneficial hemodynamic and metabolic effects of intraaortic balloon counterpulsation appear to prevent furhter, possibly critical, myocardial damage in the perioperative period.

Assisted Circulation↗
PubMed1977

Femoral neuropathy associated with anticoagulant therapy.

The English literature concerning femoral neuropathy associated with anticoagulant therapy is reviewed. Anatomical dissections were carried out in order to determine how the neuropathy might be produced. It is postulated that hemorrhage occurs within the iliacus muscle and that a pressure neuropathy of the femoral nerve ensues. Conservative management is recommended. The condition is probably more prevalent than previously thought, as evidenced by the fact that two cases were diagnosed in as many years by one orthopedic surgeon in a 300-bed general hospital.

Anticoagulants↗
PubMed1977

Hip fracture in the patient with Parkinson's disease.

Although treatment of the parkinsonian with hip fracture has progressed because of more effective operative intervention, the prognosis is not nearly as good as for the patient without parkinsonism. The patient's personal physician needs to be aware of possible complications, and the family should be made aware of the seriousness of the problem.

Hip Fractures↗
PubMed1976

Vertical fracture dislocation of the tarsal navicular.

An isolated vertical fracture dislocation of the left tarsal navicular with some comminution was successfully treated with open reduction and internal fixation with a screw. The surgical treatment is described, and early mobilization strongly recommended.

Adult↗
PubMed1975

A study of the human metabolism of secbutobarbitone.

The urinary excretion of secbutobarbitone (I) and its metabolites has been studied quantitatively using combined gas chromatography-mass spectrometry. After a single oral dose was given to healthy male volunteers, unchanged drug (5-9%), 2'-hydroxysecbutobarbitone (II, 1.7-3.2%), 2'-oxosecbutobarbitone (III, less than 1%), and the carboxylic acid (IV, 24-34%) were found. The kinetics of the excretion process were studied.

Barbiturates↗
PubMedDate not supplied

Intraoperative latex anaphylaxis in children: classification and prophylaxis of patients at risk.

Over a 3-year period, in 36,075 general anesthetic anesthesia procedures done at our institution, 21 patients had type I (anaphylactic) intraoperative reactions to latex (phase 1). We subsequently established a system for classification of at-risk patients with a corresponding regimen for prophylaxis used prospectively between January 1992 and July 1994 (phase II). Three groups of patients at risk for type I hypersensitivity reaction were identified, and a regimen for prophylaxis developed (based in part on protocols used in preparing patients who are allergic to radiocontrast media). Since using this protocol, the incidence of intraoperative anaphylaxis has decreased. During phase 2, 34,513 patients received a general anesthetic in the operating room, and there have been three cases of suspected intraoperative latex anaphylaxis; two of these three patients did not meet any of the risk criteria and therefore did not receive preoperative prophylaxis or avoidance of latex. Of these 34,513 patients, 86 at-risk patients received prophylaxis. A prospective study is needed to determine whether the pharmacologic prophylaxis is needed in addition to a latex-free environment.

Adolescent↗