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Biomedical subjects

J Tavernier

Publications and source records attributed to J Tavernier.

At least 145 records · Page 8Linked to original sources

Isolation and structure of a human fibroblast interferon gene.

Chimaeric plasmids containing double-stranded cDNA copies of mRNA induced in human fibroblasts by poly I . C were screened by an RNA selection method. A series of clones to which human fibroblast interferon mRNA selectively hybridized was identified. From the nucleotide sequence of the gene, the complete amino acid sequence of human fibroblast interferon was deduced. The protein is 166 amino acids long and is preceded by a 21-amino acid signal sequence.

Amino Acid Sequence↗

[Arterial hypertension and horseshoe kidney during Von Recklinghausen's disease. Angiographic study and review of the literature (author's transl)].

Angiographic studies in a young girl aged 16 years who developed arterial hypertension during the course of Von Recklinghausen's disease, demonstrated the presence of an obliterated renal artery in a horseshoe kidney. The distal arterial segment was revascularized by two homolateral ureteral arteries. A full review of the literature revealed 30 cases of renal artery lesions for which angiography had been carried out in young people with neurofibromatosis. This demonstrates the low incidence of obliterative lesions (4 cases throughout the world) which are always associated with collateral vascularization. It was not possible to apply the usual surgical treatment in our case because of the associated horseshoe kidney.

Adolescent↗

[Congenital malformations of the inferior vena cava. Embryological, anatomical and radiological study (author's transl)].

Congenital malformations of the inferior vena cava are characterized by their diversity which is related to the complexity of the embryological development of this vessel. The authors review the embryogenesis and origin of the different segments of the inferior vena cava and describe the various types of malformation, including the causative embryological abnormality, ther frequency, possible clinical repercussions, and radiological aspects. Phlebocavography is essential for the identification of the various types of abnormality. Five different types of malformation are reported. Three of these are relatively rare (left inferior vena vaca, congenital membrane of the inferior vena cava, absence of the hepatic segment with continuation of the isolated azygos segment).

Adult↗

[Inferior mesenteric arteriovenous fistula of congenital origin. A report on one case and review of the published literature (author's transl)].

A fourth case of inferior mesenteric arteriovenous fistula of congenital origin is described by the authors, who also review the general characteristics of mesenteric (or portal) arteriovenous fistulae. Early clinical signs are hemorrhage from the digestive tract and chronic anemia. Endoscopy and barium X-rays are normal, and angiography is the only means of diagnosis. Surgical treatment is essential because of the risk of hemorrhages and portal hypertension.

Adult↗

[Renal vein thrombosis in the newborn infant].

In a child born with traumatism to a diabetic mother, an acute thrombosis of the left renal vein occurred. An arteriography performed at the acute stage, established the diagnosis. The newborn received urokinase and heparin administered through an arterial catheterism. An arteriography, repeated at the 3rd day, showed an improvement in the vascularization of the kidney, which returned to normal functions. The radiological symptons of renal vein thrombosis are reviewed including the arteriography which is never used for the diagnosis in newborns. The interest of the use of urokinase and its efficiency in this disorder are discussed. This therapy harmless and efficient seems of interest. Such a therapy has to be tried because of the failure of isolated heparin-therapy and of the sequellae which may be observed after spontaneous recovery or after anticoagulant treatment.

Female↗