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Biomedical subjects

J Taranger

Publications and source records attributed to J Taranger.

At least 127 records · Page 7Linked to original sources
PubMedDate not supplied

Standard deviation score charts of skeletal maturity and its velocity in Swedish children assessed by the Tanner-Whitehouse method (TW2-20).

Reference values, means and standard deviations for skeletal maturity of Swedish children, evaluated in terms of the Tanner-Whitehouse method (TW2-20), have been expressed in mathematical functions. Almost 4000 radiograms have been assessed. The radiograms were taken on 212 children aged between one month and 18 years as part of a longitudinal study of growth and development. Up to the age of 10 years, the Swedish children had a more advanced skeletal maturation (about 0.5 SD) than the British children. Means and standard deviations have been used in preference to medians and centiles, since this makes it possible to use the results in the assessment of children with grossly deviating maturation. The selected functions were chosen in order to give a good description of the empirical distributions and no biological implications of the estimated parameters were sought. This method improves the assessment of skeletal maturity in several respects; reference values are given parametrically, which facilitates the computing of the individual standard deviation scores, and reference charts are presented for both attained scores and velocity scores (for boys between one and 13 years and for girls between one and 11 years).

Adolescent↗
PubMedDate not supplied

Height and height velocity in early, average and late maturers followed to the age of 25: a prospective longitudinal study of Swedish urban children from birth to adulthood.

A sample of 103 Swedish boys and 80 Swedish girls followed longitudinally were grouped into early, average and late maturers on the basis of age at peak height velocity. In girls there were significant differences in height between the maturity groups from 5 to 14 years of age, but the final height did not differ between the groups. In boys there were significant differences in height between the maturity groups from 12 to 16 years, no significant difference at the age of 17 years, and from 18 years of age and on, late-maturing boys were significantly taller than the early maturity boys. From 21 years and onwards they were also taller than the average-maturing boys. Thus final height differed significantly between the late-maturing boys and the other two maturity groups of boys, averaging 6.5 cm and 4.2 cm, respectively.

Adolescent↗
PubMedDate not supplied

Avidity and titers of the antibody response to two inactivated poliovirus vaccines with different antigen content.

The inactivated poliovirus vaccine is heat stabile, gives high serum IgG concentrations but less pronounced mucosal immunity and must be given as repeated injections. A new enhanced-potency Dutch inactivated vaccine could circumvent these difficulties. We compared antibody concentrations measured as neutralization or ELISA titers, and avidity of serum and salivary antibodies in children vaccinated with three doses of the earlier Swedish vaccine given over nine months or the new antigen-rich vaccine. After three doses, but not after two, serum neutralization titers for type 1 and type 3 poliovirus were higher using the new vaccine but secretory IgA levels in saliva were similar. The avidity of the serum IgG antibodies was significantly higher after two doses of the new vaccine than after three doses of the old. Thus the new vaccine gives excellent antibody responses of high titers and avidities, but should preferably be given in three doses.

Antibodies, Viral↗