Biomedical subjects

J Talmon

Publications and source records attributed to J Talmon.

20 records · Page 2Linked to original sources

PubMed1979

Immune response genes have a variable influence on the selection of antigenic foreign and self determinants of insulin.

We studied the proliferative response of mouse T lymphocytes to determinants on ungulate insulins. The immunopotency of defined determinants on the molecule was found to be regulated by three factors: the immune response genes of the immunized mouse, the mode of presentation of insulin on cells or in adjuvant, and the intramolecular cooperativity between different determinants on the insulin molecule. Autosensitization against self determinants was observed under specific conditions. These findings emphasize the variable expression of immune response genes.

Animals↗

PubMedDate not supplied

User-requirements driven learning.

This paper describes an approach for deriving classification knowledge from databases, taking into account user preferences. These preferences especially concern the trade-off between different kinds of costs and performance indicators of the classification scheme to be developed. We analyze what knowledge, provided by the user, can be used at various stages of the machine learning process to influences the development of the classifier. We restrict ourselves in this paper mainly to the generation of classification trees.

Algorithms↗