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Biomedical subjects

J T Little

Publications and source records attributed to J T Little.

23 records · Page 2Linked to original sources

Survey of general practitioners' treatment of the discharging ear.

The prescribing habits of all (401) general practitioners in the North Staffordshire health district for the treatment of otorrhoea was ascertained by questionnaire; 301 (75%) responded. Of those, 198 (66%) would not give topical treatment when the tympanic membrane was perforated. Only 41 (14%) would give topical treatment in cases of discharging grommets. Although there is a theoretical risk of ototoxicity to aminoglycosides in topical preparations, this is the most effective medical treatment and is the standard teaching advocated in specialist textbooks and practised by otolaryngologists. The results of the survey suggest that there is undue concern about possible ototoxicity and a degree of confusion in the management of this common clinical condition.

Administration, Oral↗

Tardive myoclonus.

We describe a 46-year-old, schizophrenic woman with late-onset myoclonus after treatment with antipsychotic drugs. The myoclonic jerking of the neck with synchronous contractions of the face persisted after all the antipsychotic drugs had been discontinued. Tardive myoclonus has not been documented previously.

Dibenzoxazepines↗

Histiocytic necrotizing lymphadenitis (Kikuchi's disease) of the cervical lymph nodes.

Histiocytic necrotizing lymphadenitis (HNL), or Kikuchi's disease, is a benign cause of lymph node enlargement of unknown origin. It may be mistaken for malignant lymphoma, both clinically and histologically. Though well recognized in the pathological literature few clinicians are aware of the disease. We present a case of cervical HNL and review the literature.

Adult↗