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Biomedical subjects

J T Lie

Publications and source records attributed to J T Lie.

At least 163 records · Page 9Linked to original sources
PubMed1987

Cardiomyopathy in patients with hereditary motor and sensory neuropathy.

Twelve affected persons in the third decade of life or later, and the 14 nearest age- and sex-matched unaffected relatives, of a large kindred with autosomal dominant hereditary motor and sensory neuropathy not linked to the Duffy blood group (HMSN type IA) were assessed for arrhythmia and cardiomyopathy. Cardiac abnormalities were no more frequent in the affected persons than in the unaffected relatives. The heart of a patient with HMSN type II who had died of complications of cardiomyopathy was found to have rheumatic disease-type myocarditis with Aschoff bodies. The results of this study provide further evidence against an association of cardiomyopathy and HMSN.

Adult↗
PubMed1987

Thromboangiitis obliterans (Buerger's disease) in a saphenous vein arterial graft.

Thromboangiitis obliterans (Buerger's disease) is an uncommon variety of occlusive peripheral vascular disease, occurring predominantly in young male tobacco smokers. The vascular lesion in the acute stage of thromboangiitis obliterans is distinctive and affects both the arteries and veins. Described here is an unusual case of thromboangiitis obliterans occurring in a saphenous vein used for coronary artery bypass graft in a middle-aged man who, against advice, had continued to smoke after the myocardial revascularization surgery. To the author's knowledge, thromboangiitis obliterans in arterial vein graft has not been reported previously.

Coronary Artery Bypass↗
PubMed1987

Isolated fibromuscular dysplasia of the coronary arteries with spontaneous dissection and myocardial infarction.

Fibromuscular dysplasia (FMD) is a segmental, nonatherosclerotic vascular disease of unknown etiology. Both the renal and extrarenal arterial FMD may have focally deficient or absent muscular media, and spontaneous dissection is a serious complication of this arterial wall abnormality. Although FMD may be found in virtually any small and medium-sized arteries, to our knowledge, FMD of the coronary arteries previously has not been documented convincingly in the literature. This article describes one such unusual occurrence of FMD in the coronary arteries with spontaneous dissection and myocardial infarction.

Adult↗
PubMed1987

Segmental Takayasu (giant cell) aortitis with rupture and limited dissection.

Takayasu arteritis is a chronic inflammatory disease of the aorta and its main branches, with variable extents of involvement. Rarely is it sharply localized in an isolated segment of the aorta, and it seldom occurs in an elderly person. Clinically, Takayasu arteritis produces symptoms of vascular insufficiency, predominantly because of the occlusive disease and less commonly because of aneurysmal disease of the affected arteries. An unusual case of segmental Takayasu arteritis confined to the infrarenal abdominal aorta in an elderly woman is described, in which rupture and fatal hemoperitoneum were the initial manifestations of the disease.

Aged↗
PubMed1987

Thromboangiitis obliterans (Buerger's disease) in women.

Thromboangiitis obliterans (TAO), or Buerger's disease, is a distinct clinicopathologic entity. It is a relatively uncommon cause of occlusive peripheral vascular disease. The disease is more prevalent in some geographic areas than in others, and there is a probable ethnic predisposition. Buerger's disease is decidedly rare in women; only 24 cases with histologic proof of the disease have ever been recorded, including 12 new cases described in this article. The clinical presentation and histopathology of TAO in women differ in no way from that in men. There is no evidence that the disease is milder in women, since 9 of the 12 in this series underwent amputation and the remaining 3 required reconstructive and bypass surgical intervention. Awareness of the entity and familiarity with the clinical, angiographic, and pathologic features of the disease are the key to a prompt and correct diagnosis of Buerger's disease.

Cross-Sectional Studies↗
PubMed1987

Pulmonary disease in polymyositis/dermatomyositis: a clinicopathological analysis of 65 autopsy cases.

The clinical and autopsy records of 65 patients with either polymyositis (24) or dermatomyositis (41) and pulmonary disease were reviewed. Pulmonary symptoms were recorded in 43 of the cases and included dyspnoea in 31, cough in 23, and chest pain in six. Interstitial lung disease was noted at autopsy in 27 patients; almost half of these had arthritis. Bronchopneumonia was found in 35 patients, 31 of these had received prednisone. Dysphagia was present in a similar proportion of patients with and without pneumonia. Pulmonary vasculitis was seen in five patients; pulmonary symptoms, arthritis, and raised erythrocyte sedimentation rate were present in four of these cases and all five had associated interstitial lung disease. Other pulmonary manifestations included pulmonary oedema, primary pulmonary malignancy, diffuse alveolar damage, fibrinous pleuritis, pulmonary emboli, and diaphragmatic atrophy. The mean survival after disease onset was 29 months but was much less for those with interstitial lung disease and pulmonary vasculitis.

Adult↗
PubMed1987

Coronary vasculitis. A review in the current scheme of classification of vasculitis.

Coronary artery disease is overwhelmingly atherosclerotic in nature, but inflammatory disease of the coronary arteries can be just as life-threatening a cause of ischemic heart disease in all age groups. Coronary vasculitis is not short in variety; as a clinicopathologic entity it spans the entire spectrum of systemic vasculitides. Coronary vasculitis is most closely associated with the polyarteritis group of necrotizing angiitis, vasculitis of collagen-vascular disease, and granulomatous giant cell arteritis. This article provides an overview of coronary vasculitis as an independent entity as well as a manifestation of systemic vasculitis, both the common and the uncommon varieties.

Arteritis↗
PubMed1987

Diffuse pulmonary hemorrhage. An uncommon manifestation of Wegener's granulomatosis.

We report two cases of Wegener's granulomatosis with the unusual manifestation of diffuse alveolar hemorrahge. One patient with well-documented Wegener's granulomatosis developed alveolar hemorrhage 4 weeks after leukopenia necessitated the discontinuation of cyclophosphamide. The second patient presented with pulmonary hemorrhage and died 10 days after an open-lung biopsy in which histologic features of Wegener's granulomatosis were overshadowed by alveolar hemorrhage. Lung biopsies in both cases showed marked alveolar hemorrhage and pulmonary capillaritis. The importance of recognizing capillaritis and other subtle histologic features of Wegener's granulomatosis are emphasized.

Aged↗
PubMed1987

Myocardium as emboli in the systemic and pulmonary circulation.

Myocardium as emboli is a decidedly rare phenomenon. Only three such examples were identified among 8033 consecutive autopsies performed over a ten-year period, 1976 to 1985, an incidence of 0.037%. In two of these three cases, myocardial emboli occurred in the systemic (coronary) circulation. The source of emboli was attributed to postinfarction ruptured ventricular septum in one patient, and to traumatized myocardium during surgical reconstruction of a univentricular heart (single ventricle) in the other. In the third case, myocardial emboli occurred in the pulmonary circulation, originating from excavation of the infundibulum at surgical correction of pulmonary atresia. A literature search has uncovered only five previously reported cases of myocardium as emboli, all occurring in the systemic circulation. To my knowledge, there has not been any previous report of myocardial emboli in the pulmonary circulation.

Adult↗
PubMed1986

Temporal arteritis with giant cell aortitis, coronary arteritis, and myocardial infarction.

Extracranial giant cell arteritis occurs in 10% to 15% of patients with temporal arteritis and polymyalgia rheumatica. Aorta and its major branches are most often involved and death may result from an unsuspected ruptured aortic aneurysm or aortic dissection. Involvement of coronary arteries by giant cell arteritis resulting in death from myocardial infarction is extremely rare. This article describes one such case: an 84-year-old man who died of acute myocardial infarction with the unexpected autopsy finding of giant cell aortitis and coronary arteritis, and who, three years earlier, had sudden onset of bilateral blindness and biopsy-proven temporal arteritis.

Age Factors↗
PubMed1986

Isolated granulomatous giant cell vasculitis of the pulmonary elastic arteries.

A 66-year-old man who developed an occluded left main pulmonary artery, clinically demonstrated by perfusion scan and pulmonary angiography, is described. Explorative thoracotomy revealed a granulomatous giant cell arteritis after pathologic examination of the surgically removed left lung. Detailed clinical and laboratory evaluation excluded a systemic disease.

Aged↗
PubMed1985

Myocarditis related to drug hypersensitivity.

Hypersensitivity myocarditis is an inflammatory disease of the myocardium usually related to a drug allergy. The clinical manifestations may be nonspecific, and the diagnosis is seldom suspected or established during life. We report a case that demonstrates both typical and atypical features of this disease and review the clinicopathologic correlations. This case illustrates the potential occurrence of both electrical conduction block and ventricular tachyarrhythmias, either of which may account for the mechanism of sudden death in these patients. When cardiac symptoms or electrocardiographic abnormalities (or both) occur in a setting consistent with drug allergy, hypersensitivity myocarditis should be considered. Treatment consists of discontinuation of use of the drug responsible for the reaction and, possibly, administration of corticosteroids and immunosuppressive therapy.

Adrenal Cortex Hormones↗