Search PubMed⌕ Search

Biomedical subjects

J T Kirchner

Publications and source records attributed to J T Kirchner.

9 recordsLinked to original sources
PubMed1992

Acute and chronic immune thrombocytopenic purpura. Disorders that differ in more than duration.

Immune thrombocytopenic purpura is a relatively common disease that occurs in both pediatric and adult populations. The acute form predominates in children and the chronic form is seen much more often in adults. The diagnosis is one of exclusion but often can be made on the basis of thorough history taking and physical examination and a limited number of laboratory studies. More intensive diagnostic studies, including bone marrow examination, may be needed to rule out other causes of thrombocytopenia. For patients in whom spontaneous remission does not occur, effective treatments are available, and morbidity and mortality rates are quite low.

Acute Disease↗
PubMed1991

Clostridium septicum infection. Beware of associated cancer.

For reasons that are not fully understood, there is an association between Clostridium septicum infection and carcinoma. In this article, Dr Kirchner describes the examination and treatment of a patient with C septicum infection in whom metastatic cancer was found on laparotomy.

Adenocarcinoma↗
PubMed1991

Syphilis--an STD on the increase.

The number of reported cases of syphilis, including primary, secondary and congenital syphilis, has been rapidly rising since 1987. The greatest increases have occurred in urban areas. An association between human immunodeficiency virus infection and syphilis has been established. Primary syphilis is manifested by a clean, painless ulcer called a chancre. Secondary disease often presents with constitutional symptoms and a maculopapular rash. Most infants with congenital syphilis are born without signs of infection. Serologic testing for both nontreponemal and treponemal antibodies is essential for diagnosis. Penicillin is the treatment of choice for all stages of syphilis. Case reporting and treatment of sexual contacts are two aspects of this disease that warrant greater attention from physicians.

Aftercare↗
PubMed1991

Pediatric lead screening in a suburban family practice setting.

BACKGROUND: The adverse effects of lead on behavioral and intellectual development have been recognized for many years. During the past 10 years several studies have shown that lead is toxic to children at levels previously thought to be harmless. Black children living in urban neighborhoods have been identified as being at greatest risk. METHODS: To determine whether children seen in a suburban family practice center were being exposed to lead, voluntary screening of 1-year-old patients was performed. RESULTS: Over a 7-month period venous specimens for blood lead level were obtained from 40 children. Seventeen (43%) of the children had levels of 0.0 to 0.2 mumol/L (0 to 4 micrograms/dL). Fifteen (38%) had levels of 0.24 to 0.43 mumol/L (5 to 9 micrograms/dL). Eight (20%) children had levels of 0.48 mumol/L (10 micrograms/dL) or greater. The highest value obtained was 0.82 mumol/L (17 micrograms/dL). Seventy-five percent of the children with significantly elevated lead levels resided in suburban communities. CONCLUSIONS: Children seen in a suburban family practice setting are at risk for lead exposure, and screening should be considered by primary care physicians who practice in nonurban settings.

Family Practice↗
PubMed1990

Why Nathan?

Explore the source record for details and available documents.

Adult↗