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Biomedical subjects

J T Gran

Publications and source records attributed to J T Gran.

At least 91 records · Page 5Linked to original sources
PubMed1987

Monoarthritis due to Mycobacterium chelonei.

A 48-year-old woman with infection of the tendon sheaths and proximal interphalangeal joint by Mycobacterium chelonei is described. Antibiotic therapy was not administered, and the patient recovered spontaneously.

Arthritis, Infectious↗
PubMed1985

An epidemiological survey of the signs and symptoms of ankylosing spondylitis.

An epidemiological survey of ankylosing spondylitis (AS) was performed in Tromsø, Northern Norway. Altogether 27 cases of AS were found, and the symptoms and signs of these subjects were compared to those of persons with back pain but not suffering from AS (NON-AS). The symptoms which differentiated best between AS and NON-AS were: back pain which awakened the subject at night and made him leave the bed, back pain not relieved by lying down but improved by exercise, back pain of 3 months duration or more and morning stiffness lasting 0.5 hours or more. Reduced lateral mobility of the lumbar spine, a total spinal extension of 20 degrees or less and a total spinal flexion of 40 degrees or less were signs of acceptable value for the diagnosis of AS. Clinical criteria for the diagnosis of AS, to be used both in the clinical management of patients with back complaints and in population surveys of AS are suggested.

Adult↗
PubMed1985

Prevalence of ankylosing spondylitis in males and females in a young middle-aged population of Tromsø, northern Norway.

In an epidemiological survey in Tromsø, northern Norway a prevalence of definite ankylosing spondylitis (AS) of between 1.1% and 1.4% was found (males: 1.9-2.2% and females: 0.3-0.6%). The ratio of male to female was between 3.9 and 6.1 in favour of the male sex. It was calculated that 6.7% of the B27 positive individuals had AS, and that 22.5% of the B27 positive subjects with back pain or stiffness suffered from AS.

Adult↗
PubMed1985

Spinal ankylosing spondylitis: a variant form of ankylosing spondylitis or a distinct disease entity?

In a population survey of ankylosing spondylitis (AS) seven subjects, six males and one female, had x-ray changes in the lumbar spine typical of AS but without concomitant roentgenological sacroiliitis. The overall prevalence of such cases in the population studied was 0.37%. Four out of these seven subjects carried the tissue antigen HLA-B27 (57%). The clinical and roentgenological features of these subjects are described and it is suggested that the x-ray findings represent a mild and variant form of primary or definite AS.

Adult↗
PubMed1985

The prevalence of HLA-DR4 and HLA-DR3 in healthy persons with rheumatoid factor.

The frequency of the HLA antigen DR4 has been determined in healthy individuals with serum IgM RF. HLA DR4 was found in 11.6% of these persons as compared with 27% in healthy controls. Thus, no association between IgM RF and HLA-DR4 could be found in this material of healthy individuals. HLA-DR3 was found in 35% of healthy RF-positive persons, which was no different from the 30% prevalence among healthy controls. HLA-DR3 did not seem to be associated with high immune responsiveness of RF in RF-positive individuals.

Adult↗
PubMed1985

IgG heavy chain (Gm) allotypes in rheumatoid arthritis and in healthy individuals seropositive for IgM-rheumatoid factor.

The frequencies of Gm allotypes a, x, f, b, g and n have been investigated in classical seropositive rheumatoid arthritis (RA), erosive definite seronegative RA, non-erosive definite RA and in healthy individuals with serum IgM-RF. No differences in the frequencies of these Gm allotypes were found between patients and healthy controls. It is concluded that any possible putative genes outside the HLA region involved in RA are most likely unrelated to the genes coding for the constant regions of IgG heavy (gamma) chains.

Adult↗