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Biomedical subjects

J T Cuttino

Publications and source records attributed to J T Cuttino.

32 records · Page 2Linked to original sources
PubMed1985

Renal medullary lymphatics: microradiographic, light, and electron microscopic studies in pigs.

Although renal cortical lymphatics have been extensively studied, the existence of renal medullary lymphatics has not been well documented. We studied renal microlymphatics in pig kidneys by retrograde ureteral injection of barium-sulfate-gelatin-saline mixture. Lymphatics filled as a result of forniceal rupture and interstitial extravasation. Microradiographs were correlated with histology and electron microscopy. We traced renal microlymphatic vessels from the arcuate level not only into the cortex but also into the pyramidal region, and therefore concluded that medullary lymphatics existed.

Animals↗
PubMed1981

Bladder base impressions in women: "female prostate".

Bladder base impressions due to prostate hypertrophy are a common urographic finding in older males. A similar appearance may be occasionally seen in females and presents a more difficult diagnostic problem. Sixteen such cases of bladder base defects in females at two institutions were identified. The impressions were caused by symphysis pubis asymmetry, postoperative change, urethral diverticulum, levator ani impression, or "urethral syndrome." Vaginal fibromyoma, ectopic ureterocele, and intramural bladder neoplasm can also cause this defect, although no such cases were found in this series.

Female↗
PubMed1978

Microradiographic demonstration of pyelolymphatic backflow in the porcine kidney.

Pyelolymphatic backflow occurs when intrapelvic pressure rises acutely. Although peripelvic and hilar lymphatics have occasionally been demonstrated during intravenous urography and retrograde pyelography, the patterns of intrarenal microlymphatic filling have not previously been studied radiographically in multipapillary kidneys. Microradiography was performed after retrograde ureteral injections of barium sulfate suspension in recently excised pig kidneys. Contrast filled the ducts of Bellini and extended in a retrograde fashion as far as the distal convoluted tubules. Intrarenal cortical and corticomedullary microlymphatics, as well as veins, filled following forniceal rupture and interstitial extravasation. These anatomic studies suggest that the renal lymphatics may function as an alternate pathway of drainage of an acutely obstructed kidney.

Animals↗
PubMed1977

Microradiographic studies of renal lymphatics.

Cortical and medullary lymphatics have been observed during micro-angiographic studies of canine renal allograft rejection and retrograde ureteral injection in normal pigs. Lymphatic filling results from microvascular damage in the canine model and forniceal rupture in the pig. Renal lymphatics function as an alternate route for drainage during altered physiological states.

Animals↗
PubMedDate not supplied

Collateral vessel formation: isolation of a transferable factor promoting a vascular response.

Collateral vessel formation to the kidney was induced by renal artery stenosis or embolization in six dogs. Extracts from control and collateral-forming kidneys were assessed for their ability to promote a vascular response in the hamster cheekpouch. The highly significant response evoked by particulate and soluble fractions of cytoplasm from collateral-forming kidneys suggests a humoral element in collateral vessel formation.

Animals↗
PubMedDate not supplied

Lymphatic visualization during renal transplant rejection.

Intrarenal microlymphatic filling was observed during a microangiographic and histologic study of unmodified canine allograft rejection. The extent of lymphatic visualization was correlated with the pathophysiologic state of the allograft. An example of renal lymphatic visualization following arterial perfusion of a human specimen is also presented. During early rejection, as microvascular and histologic alteration became more severe, there was prominent visualization of lymphatics. However, in late rejection, as cortical necrosis developed, lymphatic filling was less evident. Lymphatic visualization following arterial perfusion during rejection depends on progressive loss of microvascular integrity, contrast extravasation and subsequent filling of lymphatics which are acting as an alternate route of drainage for the excess interstitial edema present due to immune injury.

Angiography↗
PubMedDate not supplied

Pyelovenous and pyelolymphatic backflow during retrograde pyelography in renal vein thrombosis.

Pyelovenous and pyelolymphatic backflow have been observed during retrograde pyelography in three patients with renal vein thrombosis. The radiographic patterns of backflow following experimental unilateral renal vein occlusion in rabbits were analyzed and correlated with the clinical findings. Capsular, perihilar, periureteric, and retroperitoneal collateral vein networks and lymphatic channels were demonstrated on the venous occluded side. The appearance shown in the experimental study correlate well with the clinical observations.

Adolescent↗
PubMedDate not supplied

Experimental renal papillary necrosis in rats: microangiographic and tubular micropuncture injection studies.

Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular micropuncture injection studies. During early stages of RPN, microvascular studies revealed reduced perfusion of vasa recta, and tubular injection studies showed unobstructed tubules and collecting ducts. In the late stage, medullary vascular obliteration and intratubular debris with tubular obstruction were seen. This evidence suggests that RPN in this model is initiated by vasoconstriction rather than direct tubular toxicity.

Angiography↗