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Biomedical subjects

J T Carpenter

Publications and source records attributed to J T Carpenter.

49 records · Page 3Linked to original sources
PubMed1979

Splenectomy for hematologic disease.

One hundred and thirty splenectomies were performed at the University Hospital in Birmingham for hematologic disorders during a 12 year period. There were seven deaths of which four were related to sepsis in patients with malignant growths which probably impaired immune competence. Splenectomy was found to be uniformly satisfactory for hereditary hemolytic anemia, for hypersplenism complicating rheumatoid arthritis and for the rare instance of primary hypersplenism. Splenectomy was usually salutary in didopathic thrombocytopenic purpura and in antoimmune hemolytic anemia. When done for diagnosis, splenectomy was definitive in about 50 per cent of the instances. Individual patients with thrombotic thrombocyeosinophilia syndrome benefited. Splenectomy for hypoplastic or aplastic anemia in an actual circulation offered only questionable benefit and is rarely necessary for hyperplenism secondary to portal hypertension.

Adult↗
PubMed1977

Meditation, esoteric traditions--contributions to psychotherapy.

This article is a brief introduction to several different Eastern systems of philosophy and therapy. It surveys the Buddhist contributions and several contemporary applications of traditional meditation techniques within the framework of modern psychologic science. It is suggested that meditative exercises produce three therapeutic gains: insight into repetitive, self-defeating patterns of behavior, desensitization of painful thoughts, and the conditioning of the central nervous system.

Attitude↗
PubMed1975

Mithramycin in the treatment of systemic mastocytosis.

A patient had systemic mastocytosis of 16 years' duration, with urticaria pigmentosa, osteopetrosis with severe bone pain, mastocytosis of the bone marrow with myeloid metaplasia, gastrointestinal malabsorption, and Cushingold features associated with prolonged usage of corticosteroids. Treatment with a single dose of mithramycin resulted in an abrupt disappearance of the patient's generalized bone pain, but it had little effect on his histamine release-type symptomatology.

Adult↗
PubMed1975

Erythrocyte protoporphyrin in the detection of iron deficiency.

Any decrease in the availability of iron for incorporation into the heme moieties of hemoglobin results in an increase in the erythrocyte protoporphyrin concentration. Our aim was to compare protoporphyrin concentrations, determined spectrophotometrically, with body iron stores, as assessed from the amount of iron demonstrable by Prussian blue staining of bone marrow aspirates. The mean protoporphyrin concentration (175 mu-g/dl) in the erythrocytes of a group of patients with markedly decreased stainable marrow iron or no iron was significantly greater (P less than .001) than the mean concentration (76 mu-g/dl) in a comparable group with adequate bone marrow iron stores, except in the presence of certain interfering conditions. These results suggest that the erythrocyte protoporphyrin test may be a useful addition to the methods now available for assessing disorders of heme synthesis, the most common of which is iron deficiency.

Adult↗
PubMedDate not supplied

Intrarenal chloroma causing obstructive nephropathy: CT characteristics.

A patient presented with unilateral obstructive nephropathy due to a granulocytic sarcoma (chloroma) arising within the renal pelvis. To the best of our knowledge, granulocytic sarcoma has not previously been described either arising in the urinary system or occurring during induced remission of disease. Even in the absence of other evidence of active disease, with a history of leukemia, this lesion should be considered in the differential diagnosis of collecting system tumors, as recommended therapy is nonsurgical.

Adult↗