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Biomedical subjects

J T Andrews

Publications and source records attributed to J T Andrews.

At least 37 records · Page 2Linked to original sources
PubMed1982

Comparison of sodium and calcium heparin in prevention of venous thromboembolism.

The relative efficacy of sodium and calcium heparin in preventing venous thromboembolism and their relative side-effects were studied in 234 high-risk patients in a randomised, double-blind, placebo-controlled trial. The two heparin preparations were from the same batch and in the same concentration, and were given in a dose of 5000 U 12 hourly. Positive leg scans were found in 19% after placebo, 12% after sodium heparin and 8% after calcium heparin. Bruising at the injection site was more common after calcium heparin (66%) than after sodium heparin (53%) or placebo (38%). Pain at the injection site was also more common after calcium heparin (26%) than after sodium heparin (8%) or placebo (6%). Changes in the activated partial thromboplastin time were small and did not correlate with leg scan results or bruising. While there was a tendency for calcium heparin to be possibly more effective, it was followed by significantly more local haematoma and pain.

Adult↗
PubMed1979

67Gallium uptake in psittacosis infection.

67Gallium citrate isotope scanning was performed in a febrile patient with pneumonitis and hepatitis who was later shown to have psittacosis. Focal isotope uptake was detected in both lungs in the absence of radiological changes. There was no enhanced concentration in the liver where inflammatory cell infiltration was slight.

Female↗
PubMed1979

Evaluation of the Gambro Lundia Major 1.36 m2 disposable parallel plate dialyzer.

The Gambro Lundia Major 1.36 m2 dialyzer was assessed in vivo in ten hemodialysis patients. Urea and creatinine clearances (measured as whole blood values at 60 minutes with a blood flow rate of 200 ml/minute) were 166 +/- 8 m/minute (mean +/- standard error of the mean, n = 9) and 115 +/- 4 ml/minute (n = 11). The creatinine clearance is 15% lower than in vitro data. There was a marked decrease in urea and creatinine clearance with third use of the dialyzer. The ultrafiltration rate was 490 ml/hour/100 mmHg. The priming volume was 125 ml (at a transmembrane pressure of 100 mmHg) and residual blood volume in the dialyzer was 0.57 +/- 0.11 ml (n = 5). The handling, storage and ease of disposal of the dialyzer is better than previous models and its performance characteristics are clinically acceptable.

Adult↗
PubMed1978

Microleakage of several amalgam systems: an animal study.

Restorations placed without the application of cavity varnish to the cavity walls and the cavosurface angle exhibited significant marginal leakage after 24 hours and 3 months. At the end of 6 months a decrease in leakage was exhibited with all alloys. With the exception of two specimens, restorations placed after coating the cavity walls and the cavo-surface angle with cavity varnish demonstrated slight or no marginal leakage at all time intervals. The results of this study indicate that the marginal leakage of a conventional filing alloy, a conventional spherical alloy, and two high-copper alloys are approximately the same. The corrosion-resistant high-copper alloys showed the same degree of marginal leakage as the conventional alloys. The results of this study agree with those of a previously reported in vitro study on amalgam leakage.

Animals↗
PubMed1978

Microleakage of several class V anterior restorative materials: a laboratory study.

The study was designed to evaluate the marginal leakage of abraded gingival areas in extracted teeth using five anterior composite resin acid-etch restorative materials and a glass ionomer cement, ASPA. In using three of the composite resin restorative materials, Simulate, Cervident, and Concise, there was a layer of unfilled resin between the etched tooth surface and the composite resin. Restodent and Enamelite were placed directly on the etched tooth surface. The results of the study indicate that there is a significantly greater degree of marginal leakage at the gingival margin than there is at the occlusal or incisal margin of composite restorations. In addition, greater marginal leakage was observed in those restorations where no layer of unfilled resin was placed between the etched tooth surface and the composite resin. The glass ionomer cement showed no marginal leakage at intervals of one day, three months, and six months; however, a small amount of leakage was observed at the incisal or occlusal and gingival margins at a year on half of the autoradiographs. A study has been initiated to determine leakage patterns around composite resin restorations placed in teeth with naturally occurring cervical erosion or abrasion.

Acrylic Resins↗