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Biomedical subjects

J Svejda

Publications and source records attributed to J Svejda.

At least 91 records · Page 5Linked to original sources

[The development of the filiform papillae in the human tongue].

Filiform papillae are described in a 4-month-old fetus, in premature children (22-36 weeks) and in children who died soon after birth. Under the scanning electron microscope papillae filiformes often displayed tubercles appearing either independently or arising near the base of the tongue from obliquely running ridges dividing afterwards into tubercles. Some SEM specimens showed further development of papillae from tubercles and cylindrical papillae into papillae quite similar to those found in a fully developed tongue. They were however significantly smaller. Filiform papillae are more varied in the stage of development than in the fully developed tongue, because developmental stages could be observed here. We could also see spheroid papillae with tiny processes on the top or large scales on the circumference besides the above mentioned formations. Even places with "hairs" resembling those of the hair-tongue were found. These atypical findings were most likely pathological changes resulting from hypoxia before death.

Female↗

A freeze-etch study of occurrence of nuclear pores in normal and tumor cells.

A freeze-etch study of nuclear pores performed on human lymphocytes, epidermal and corneal cells, on hamster fibroblasts, on rat and hamster sarcoma cells and cells from a human malignant melanoma, revealed that the frequency of pores as a part of very important biological cellular structures increases in proliferating cells, and that there is a statistically significand difference between normal and tumor cells. Once produced the pores maintain and their frequency practically does not change. The pores are randomly distributed on the nuclear envelope. Markham rotating method revealed an octa- or nonaedric outside shape of the pores and round inner margin with eight or nine granules. One bigger granule was found in the center of the pores. The granule is with a great probability filamentously attached to the margin of the pore. Fibrillar structures running to the pores on inner surface of nuclear envelope as far as the chemical composition of granules need special cytochemical examinations.

Animals↗