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Biomedical subjects

J Stefan

Publications and source records attributed to J Stefan.

36 records · Page 2Linked to original sources

[Heart antibodies in sudden death].

Anti-heart antibodies detected by indirect immunofluorescence were found in the blood of persons deceased suddenly of heart failure more often (36,7%) than in those who died of other causes (16,6%). Antibodies were found the most frequently in rheumatic heart failure (50%), in other heart diseases (50%), and in ischemic heart disease (35,5%). In ischemic heart disease there was a high level of antibodies in patients with chronic heart aneurysm (66,6%) as compared with low level in those with acute infarction (16,6%). Obviously, antiheart antibodies often accompany a heart disease without being closely related to the heart failure. A negative result of serological examination does not exclude a heart disease.

Autoantibodies↗

Reactivity of antistreptococcus hyperimmune sera with human myocardial tissue.

Antimyocardial antibodies were determined in hyperimmune rabbit sera against group A streptococci. The detection method was indirect immunofluorescence in human myocardial tissue sections. Positively reacting sera were absorbed with group A streptococcus cell walls and cytoplasmic membranes, the objective being to locate the cross-reacting antigen in the streptococcus cell under the given experimental conditions. Cell walls gave the better absorption results. Whether or not the streptococci possessed the Fc-reacting factor was without influence on the absorption result.

Antibodies, Bacterial↗

[The mechanism of the origin of acute subdural hemorrhage].

Acute subdural haemorrhage was found in 220 persons, i. e. 30.1% of a group of 731 of those who died as a result of blunt impact head injuries. The result of an analysis confirmed the significant effect of the direction and site of the blow on the development of acute subdural bleeding. Subdural haemorrhage was found the most frequently in violent blows coming from the side on the temporal region [43.4%] and in blows coming from behind on the occipital region [40.5%]. Another point proved was that in blows dealt in these directions the highest incidence of subdural haemorrhage was due to significantly more frequent development of bleeding in the group of middle-aged persons over 50, and that at the site of contrecoup. Proceeding from the results of his analysis the author stresses the significance of brain contusion and laceration for the development of acute subdural haemorrhage.

Adult↗

[Analysis of the causes of fatal burns].

In 500 casualties who died from thermal injuries comprising 314 men and 186 women, all above 15 years of age, the causes of the injuries were analyzed. In 266 the injuries were contracted at home, 140 were industrial injuries and 94 other injuries (transport, criminal, agriculture). The authors discuss the causes of injuries and their frequency. Finally they draw attention to the adverse development of non-occupational injuries in the home.

Adolescent↗

[Immunofluorescent demonstration of heart muscle antibodies in sudden deaths].

The method used for the demonstration of antibodies was the indirect immunofluorescent method. In 30% of patients suddenly dying from ischemic heart disease the sera contained antibodies binding on the sarcolemma and the subsarcolemmal layer of muscle fibres. The results of immunofluorescent examinations have been compared with the gross and microscopical findings in the heart.

Antibodies↗