Search PubMed⌕ Search

Biomedical subjects

J Starck

Publications and source records attributed to J Starck.

At least 73 records · Page 4Linked to original sources
PubMed1986

Hand-grip force in lumberjacks: two-year follow-up.

Hand-grip force was measured in 63 professional lumberjacks in 1978 and again in 1980. Lumberjacks with vibration-induced white fingers (VWF) had lost 21% of their muscle force during the two years. Lumberjacks with no hand-arm symptoms had lost 5% of their muscle force in the same time period. Lumberjacks with subjectively diminished hand muscle force had a slight increase in muscle force during the follow-up time. These results suggest that long-term exposure to vibration causes a decrease in muscle force.

Adult↗
PubMed1986

Finger peripheral resistance during local cold provocation in vasospastic disease.

Finger systolic blood pressure (FSBP), finger arterial inflow (FAI), finger venous opening pressure (FVOP), and finger peripheral resistance (FPR) were evaluated in 56 workers exposed to chain-saw vibration. Twenty-one of the workers were free from vibration-induced white finger (VWF). In 17 subjects VWF had ceased; 12 of the subjects had active VWF; 6 subjects had Raynaud's disease. The subjects were examined in a supine position under thermoneutral conditions with strain-gauge plethysmography. Cold provocation of the finger caused a significant reduction in FSBP in the groups with Raynaud's disease and active VWF. The finger circulation of the subjects with active VWF and that of those with Raynaud's disease showed a significantly reduced FAI when compared with that of the symptom-free referents. Finger cooling produced a gradual reduction in the FVOP and a significantly increased FPR of the subjects with active VWF and in those with Raynaud's disease. FPR was already increased in the Raynaud's disease group at the beginning of the test, whereas it increased in the VWF group as the temperature fell. The results suggest that in Raynaud's disease the fault is in the level of activity of the sympathetic outflow and in VWF it is peripheral mechanisms controlling the vessel tone.

Cold Temperature↗
PubMed1986

Circulatory reaction to heat and cold in vibration-induced white finger with and without sympathetic blockade--an experimental study.

Central nervous, sympathetic mechanisms and local factors influencing the vascular response to cold in the finger skin were studied with plethysmographic and laser-Doppler methods in a chamber with controlled temperatures from 45 to about 5 degrees C, with and without sympathetic finger blockade. Blood flow and pressure were assessed after finger occlusion, together with finger heating and cooling, in workers with vibration-induced white finger (VWF) and in healthy persons not exposed to cold or vibration. Finger blood flow at vasodilatation, as measured by finger arterial inflow (FAI) after occlusion was smaller in the VWF group than in the reference subjects both with and without anesthesia, and capillary flux in the anesthetized finger tended to be smaller. At vasoconstriction, with or without anesthesia, the VWF subjects had lower FAI values than the referents. The studied flow and pressure variables differed considerably between the groups. The peripheral resistance of the VWF subjects was higher than that of the referents. This difference was the most pronounced after finger anesthesia. A possible pathogenetic mechanism in VWF is an increase in peripheral resistance due to a local defect in the vessels, with subsequent reduction in flow and intramural pressure.

Adult↗
PubMed1986

Digital high-speed sampling of combined exposure to noise and vibration.

The digital high-speed sampling technique was applied to simultaneous measurements of exposure to noise and vibration among workers who used hand-held power tools in a shipyard. The transducers were two accelerometers and two microphones which measured the transmission of vibration acceleration from the handle of the tool to the wrist and the attenuation of noise by the earmuffs. The measurements were taken by a microcomputer-controlled digital multichannel sampling unit. An analogue-digital converter was used with a 100-kHz scanner for multichannel signal acquisition in the 10 kHz bandwidth. The sound pressure was A-weighted, and the vibration acceleration was both unweighted and weighted according to the guidelines of the International Organization for Standardization. Impulsiveness was determined as the difference between the peak and root-mean-square levels. The noise exposure was 81 dB during grinding and 85 dB during hammering. The earmuffs provided protection against impulse noise at least when the impulses contained high frequencies. The transmission loss of vibration acceleration between the tool handle and wrist was 45 dB for grinding and 29 dB for hammering. The transmission of noise and vibration was affected by the frequency content and impulsiveness of the signals.

Fingers↗
PubMed1986

Impulsiveness of vibration as an additional factor in the hazards associated with hand-arm vibration.

Impulsiveness is defined as the difference between peak and root-mean-square signals. As the difference varies in time, the cumulative distribution function has been used to describe the probability of achieving a certain value of impulsiveness. To make numerical comparison of different vibration signals possible, an impulse index has been selected from the cumulative distribution function. Symptoms of vibration-induced white finger were observed and compared to those expected on the basis of measurements taken according to guidelines of the International Organization for Standardization (ISO). Agreement was found for chain-saw vibration. In the case of pedestal grinding, the ISO draft underestimated the hazardous effects of vibration. Stone workers using pneumatic hammers were exposed to highly impulsive but asymmetrical vibration. The corresponding asymmetry was not, however, observed between the symptoms of the left and right hands, a finding which indicates that coupling between the tool and the hand is important for impulse vibration. The results suggest that the impulse character of vibration increases the risk of vibration-induced pathology. The analysis of high-impulse acceleration peaks obtained by the method presented in this study could provide additional data necessary to improve risk assessment.

Fingers↗
PubMed1986

Cold provocation tests in the evaluation of vibration-induced white finger.

Two types of cold provocation tests, a classical test with immersion of the hand in cold water and the evaluation of finger systolic blood pressure (FSBP) during local cooling, were administered to forest workers. Raynaud's phenomenon in the classical test correlated positively with the number of disabled phalanges, recovery time, and frequency of attacks. It did not correlate with the severity of paresthesia of the hands and arms. Repetition of the test enhanced the number of positive results. A significant reduction in the FSBP was observed in 22 and 25% of the subjects with inactive and active forms of vibration-induced white finger (VWF), respectively. In the same groups of subjects the classical cold provocation test yielded positive results in 7 and 25% of the subjects, respectively. A cold provocation test was found to produce a positive result even some years after the cessation of VWF attacks. The rather low severity of VWF among the examined subjects may explain the lack of positive test results. FSBP measurement was not superior to cold provocation by water immersion, but it is recommended because it is easier to standardize and more convenient for the test subject.

Adult↗
PubMed1986

Pathophysiological and hygienic aspects of hand-arm vibration.

A review of current knowledge on the pathophysiological and hygienic aspects of the hand-arm vibration syndrome is given. Hemodynamic measurements indicate that the primary factor in vibration-induced white finger is an increase in the peripheral resistance of finger circulation that is present after local and general cooling. The reason for this increase is not known, but it is postulated that an excessive affinity of vasoactive substances for the efferent receptors exists, this affinity being potentiated during local cooling of the digits. So far, the hygienic rating of hazardous vibration in individual work phases is of limited value in diagnosing possible cases, but this rating does provide guidelines for general risk assessment. A consideration of several factors, eg, intermittency of the work, duration of daily exposure, impact of vibration, individual physiological responses, climate, etc, might improve the accuracy of the rating, but the influence of these factors on the development of the vibration syndrome is still poorly understood. Of various preventive measures, only those that significantly reduce vibration will be beneficial in the long run.

Fingers↗
PubMed1986

Vibration syndrome among Finnish forest workers, a follow-up from 1972 to 1983.

A longitudinal survey on the prevalence of vibration syndrome among professional forest workers was conducted from 1972 (118 workers) to 1983 (206 workers). The prevalence of vibration-induced white finger (VWF) was 40% among the workers in 1972; it gradually declined to 5% in 1983. Three new workers developed VWF symptoms during the follow-up period. They had only used saws equipped with antivibration handles. The prevalence of VWF has decreased mainly due to the reduction of chain-saw vibration. The prevalence of paresthesias of the hands and arms declined from 78% in 1972 to 37% in 1976, and then increased to 51% in 1983. The recent increase was thought to be due to static muscle load and the ageing of the workers. No correlation was found between the severity of VWF and peripheral nerve symptoms. No significant changes in muscle fatigue occurred during the follow-up period; it was present in about 10-15% of the workers. The forest workers subjectively assessed musculoskeletal load and strain as being more harmful than the symptoms of vibration syndrome. The preventive measures aimed at reducing chain-saw vibration, implemented since 1970, have been beneficial and explain the decreased prevalence of VWF.

Cross-Sectional Studies↗
PubMed1986

Vasomotor oscillation in vibration-induced white finger.

Vasomotor oscillation at different ambient temperatures, with and without anesthesia of the finger nerves, was studied in six persons with vibration-induced white finger (VWF) and in 10 referents. The power spectral density (PSD) of the Fourier transform of the laser-Doppler flowmeter signal from the finger pad vessels was analyzed. In both groups, the PSD of the vasomotor oscillation in the frequency range of 0.05-0.25 Hz was more pronounced in a cold than in a hot environment. Without finger nerve anesthesia, the oscillations of the referents were significantly greater (p less than 0.01) than those of the VWF subjects (PSD -34.4 dB and -41.6 dB, respectively). With anesthesia of the finger vasomotor nerves, the PSD was reduced in both groups. In the anesthetized finger there was no statistically significant group difference. Thus the myogenic component of the vasomotor activity was the same in the referents as in the VWF subjects. The results show that the autonomic neural influence on vasomotor oscillation in skin of the finger pad is weaker in persons with VWF. This weakness may be a sign of peripheral neuropathy, which may lead to a denervation syndrome causing hypersensitivity of the adrenoceptors to cold.

Adult↗
PubMed1985

Combined effects of noise, vibration and visual field stimulation on electrical brain activity and optomotor responses.

Eye movements and electroencephalographs (EEG) were recorded in intact rabbits during an optokinetic test. The animals were exposed to pure tone noise (85 dB at 4000 Hz), impulse noise (159 dB), and vibration directed at the abdomen (amplitude 0.9 mm at frequencies of 40, 80, and 120 Hz). The velocity of optokinetic nystagmus (OKN) significantly increased with these stimuli. The increase seen with vibration was greater than the noise-induced increase. The response was strongest when noise and vibration were combined. The increase in OKN induced by vibration was successive and dependent on frequency. The increase was weakest during exposure to vibration at 40 Hz and strongest at 120 Hz. EEGs of the dorsal hippocampus, amygdaloid complex, midbrain reticular formation, and frontal motor cortex were all activated during noise and vibration exposure, but activation of the hippocampal EEG was the most closely related to the increase in OKN. Combination of the different stimuli indicated that their interaction could not be predicted on the basis of responses to single stimuli, and, in most cases, the result was indifference due to the high alerting effect of vibration alone. The findings can be related to the non-specific dizziness found in aerospace workers exposed to excessive noise and vibration.

Animals↗
PubMed1985

Vibration-induced neuropathy among forestry workers.

The neurological findings of 217 forestry workers were evaluated during a compulsory annual health examination. Vibration detection thresholds were determined for the left hand and foot. The handgrip forces were measured for both hands. A reduction in the vibration detection threshold or handgrip force was not associated with clinical neuropathy. Polyneuropathy was found in 4% of the lumberjacks whereas neuropathy restricted to the arms was found in 7.5% of the lumberjacks. The neuropathic findings were not linked with alcohol consumption but were associated with a history of numbness in the hands and diminished muscle force. The findings support the concept that local vibration can cause neuropathy in the arms, but the mechanism of vibration-induced neuropathy still remains uncertain.

Adult↗
PubMed1984

Role of the gonad cytoplasmic core during oogenesis of the nematode Caenorhabditis elegans.

In order to elucidate the function of the cytoplasmic core (or rachis: a structure specific of the nematode gonads), we have carried out a cytological study of this structure in the free-living nematode Caenorhabditis elegans, in wild-type and in several mutant strains showing an abnormal gametogenesis. We also performed an ultrastructural radioautographic study of RNA synthesis during oogenesis in order to examine the part played by the rachis in the transport of nutritive substances. Our results evidence for the first time a metabolite transfer from the germ cells to the cytoplasmic core and lead us to assign to the core a trophic role linked to oogenesis. A statistical analysis of silver grain distribution has led us to conclude that there is no accumulation of RNA labelling in any part of the cytoplasmic core. In addition, our studies performed on sterile mutant strains suggest that the cytoplasmic core may have a specific function in oogenesis determination.

Animals↗
PubMed1984

High impulse acceleration levels in hand-held vibratory tools. An additional factor in the hazards associated with the hand-arm vibration syndrome.

The measurement of the root-mean-square (rms) acceleration of vibration does does not take into consideration the short high peak values of the vibratory signal, which may be a hazard contributing to the development of vibration-induced disease. A method for evaluating the impulse character of vibratory signals is given, and impulsiveness is defined as the difference between the peak and rms signals. Measurements were taken during pedestal grinding, during chain sawing with three different generations of saws, and during chiseling with a pneumatic hammer. The measurements comprised (i) analyses done according to the International Organization for Standardization (ISO) draft, (ii) an evaluation of impulsiveness, and (iii) an analysis of the short-time history transient. The risk of vibration-induced white fingers was estimated by the ISO method, and the results were compared with those observed. It was found that the analysis of impulsiveness provided additional data and partly explained the observed symptoms of vibration-induced white fingers. The parameters for the impulsiveness of the vibration signal agreed with the short-time history analysis.

Humans↗
PubMed1983

Vibration syndrome and vibration in pedestal grinding.

At one Finnish foundry all the workers had typical symptoms of vibration induced white finger (VWF) after they began using a new type of pedestal grinding machine. The objectives of this study were to establish the severity of the symptoms and the difference in vibration exposure between the new and the old machines. Vibration detection thresholds and grip forces were measured, as well as the vibration in the casting and in the wrist simultaneously. The mean latency for VWF among the grinders was 10.3 months after the change of pedestal grinding machines. All the grinders had numbness in their hands. The vibration detection threshold was significantly higher for the grinders than for their referents. At the same circle speed, the new wheels caused vibration levels up to 12 dB more than the old wheels. The circle speed had a slight influence on the vibration. The vibration levels of light (0.5 kg) casting were up to 25 dB higher than the heavy (5 kg) casting. The use of a pneumatic pressing device decreased the vibration levels in the wrist by 5-10 dB. The increase in vibration, which occurred when the new wheels were taken into use, was too small to explain such a dramatic outbreak of VWF. This led to the conclusion that some other feature such as the impulse character of the vibration also contributed to the effects of vibration.

Adult↗
PubMed1982

Frequency of rheumatic diseases in patients with acute anterior uveitis.

The frequency of associated rheumatic diseases was studied in 271 patients with acute anterior uveitis (AAU). In a retrospective examination of 154 patients with AUU (mean follow-up period of 6 years) associated rheumatic symptoms were observed in 64 (41.6%). Forty-one patients (26.6%) had ankylosing spondylitis and 39 (25.3%) manifestations of Reiter's disease. Radiographic sacro-iliitis was seen in 35 (34%) of 103 consecutive x-ray examined patients with AAU. Furthermore, in another series of 38 patients, who all, in addition to having AAU, also complained of low back pain or had manifestations of Reiter's disease, 23 (60.5%) had radiographic sacro-iliitis. Classical ankylosing spondylitis was more frequent in men with AAU whereas milder forms of the disease occurred more equally in both sexes. HLA-B27 occurred in 35 (87.5%) of 40 HLA-typed patients with AAU. Associated rheumatic diseases occurred in 18 (51.4%) of the 35 HLA-B27 positive patients but in none of the HLA-B27 negative patients. The results support the hypothesis that a pleiotropic HLA-B27 associated gene may determine the susceptibility to AAU, sacro-iliitis, ankylosing spondylitis, and Reiter's disease.

Acute Disease↗
PubMed1981

Hand-arm vibration in the aetiology of hearing loss in lumberjacks.

A longitudinal study of hearing loss was conducted among a group of lumberjacks in the years 1972 and 1974--8. The number of subjects increased from 72 in 1972 to 203 in 1978. They were classified according to (1) a history of vibration-induced white finger (VWF), (2) age, (3) duration of exposure, an (4) duration of ear muff usage. The hearing level at 4000 Hz was used to indicate the noise-induced permanent threshold shift (NIPTS). The lumberjacks were exposed, at their present pace of work, to noise, Leq values 96-103 dB(A), and to the vibration of a chain saw (linear acceleration 30-70 ms-2). The chain saws of the early 1960s were more hazardous, with the average noise level of 111 dB(A) and a variation acceleration of 60-180 ms-2. When classified on the basis of age, the lumberjacks with VWF had about a 10 dB greater NIPTS than subjects without VWF. NIPTS increased with the duration of exposure to chain saw noise, but with equal noise exposure the NIPTS was about 10 dB greater in lumberjacks with VWF than without VWF. With the same duration of ear protection the lumberjacks with VWF consistently had about a 10 dB greater NIPTS than those without VWF. The differences in NIPTS were statistically significant. The possible reason for more advanced NIPTS in subjects with VWF is that vibration might operate in both of these disorders through a common mechanism--that is, producing a vasoconstriction in both cochlear and digital blood vessels as a result of sympathetic nervous system activity.

Adult↗
PubMed1980

Vibration-induced decrease in the muscle force in lumberjacks.

Isometric maximal hand grip force was measured with a strain gauge dynamometer in 91 lumberjacks and 31 controls during a 2-min compression-relaxation task. Measurements were carried out on both hands with and without simultaneous vibration exposure. The muscle forces of older subjects were smaller than those of younger men, independent of occupational vibration exposure. The fatigue curves of lumberjacks and control subjects had the same shape. During vibration exposure in the test, the forces diminished in the left hand significantly in the lumberjacks but not in the control subjects. The force level of fatigue curves of the lumberjacks with a history of diminished grip force was lower and decreased more during vibration exposure than in the lumberjacks with a history of normal grip force. The reduction in the hand grip force during vibration exposure in the lumberjacks seemed to be linked to lesions in the peripheral nerves and to activation of a tonic vibration reflex, but probably not to circulation disturbances. The fatigue mechanism seemed to be the same in lumberjacks and control subjects.

Adult↗