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Biomedical subjects

J Sowa

Publications and source records attributed to J Sowa.

At least 37 records · Page 2Linked to original sources

Long-term treatment of onchocerciasis in children with low doses of diethylcarbamazine.

Two groups of children were treated daily with 12.5 or 25 mg diethylcarbamazine for five months and a further group with 12.5 mg daily for seven weeks; 88 children completed the course. The trial was under constant supervision and ophthalmic and parasitological examinations were carried out at approximately one-month intervals. The acceptability of the drug was poor owing to adverse reactions, but the clinical response to treatment good.

Child↗

Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.

Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication.

Animals↗