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Biomedical subjects

J Slots

Publications and source records attributed to J Slots.

238 records · Page 14Linked to original sources
PubMedDate not supplied

Severe periodontitis in a 5-year-old girl with hyperimmunoglobulin E syndrome.

The hyperimmunoglobulin E syndrome (HIES) is a multisystem disorder that affects the: (1) dentition; (2) skeleton; (3) connective tissues; and (4) immune system. Little is known about periodontal manifestations of the syndrome. The purpose of this report was to describe a 5-year-old girl with suspected autosomal-recessive HIES syndrome who revealed profusely bleeding and painful gingiva and generalized aggressive periodontitis. A polymerase chain reaction (PCR)-based microbiological examination detected Porphyromonas gingivalis, Tannerella forsythia, Prevotella nigrescens, Treponema denticola, Eikenella corrodens, and Campylobacter rectus in the deep periodontitis lesions. The extraction of all deciduous teeth due to a poor prognosis and risk of systemic infection led to resolution of the oral inflammation. Long-term follow-up is required to determine the periodontal prognosis of the erupting permanent teeth.

Bacteria, Anaerobic↗
PubMedDate not supplied

Identification of Bacteroides gingivalis by fluorescent antibody staining.

Reactivity with the conjugates to the 4 serogroups A, B, C and C-1 of the former taxon Bacteroides melaninogenicus and with antisera to B. gingivalis and to oral strains of B. melaninogenicus subsp. intermedius, was studied by fluorescent antibody staining (FAS) on strains representative of the black-pigmented Bacteroides: B. asaccharolyticus, B. melaningogenicus subsp. intermedius, B. melaninogenicus subsp. melaninogenicus, B. melaninogenicus subsp. levii, B. melaninogenicus subsp. macacae and B. gingivalis. The strains of B. gingivalis only reacted with the homologous antiserum and failed to react with any of the other immunoreagents tested indicating that the oral strains of asaccharolytic black- pigmented Bacteroides belong to a serogroup distinct from those currently serogrouped. This serological characteristic corroborates the definition of the new species B. gingivalis which has been proposed on the basis of phenotypic and genetic characteristics different from that of B. asaccharolyticus and can be used for their discrimination. FAS appears to be a reliable method for identification of B. gingivalis, a suspected major periodontopathic organism.

Bacteroides↗
PubMedDate not supplied

Microbiologic and clinical study of polytetrafluoroethylene membranes for guided bone regeneration around implants.

This study determined the microbiota of the mucosa- and implant-facing parts of expanded polytetrafluoro ethylene augmentation material, and the influence of major periodontopathogens on the healing process associated with guided bone regeneration around dental implants. Seventeen patients with nine dehiscence and eight extraction defects were studied. Prior to surgery and at membrane removal, microbial morphotypes, total viable counts, and the occurrence of selected microbial species were examined by phase-contrast microscopy, nonselective and selective cultures, and DNA probes. Nine sites with submerged barrier membranes throughout the 9-month study were free of cultivable microorganisms and experienced significantly more osseous healing than eight sites with prematurely exposed membrane. Patients with few or no deep periodontal pockets demonstrated significantly fewer residual osseous defects than patients showing several pockets of increased depths. In addition, patients with prematurely exposed membranes revealed several deep periodontal pockets. Three patients with less than 1 mm of osseous gain yielded either Porphyromonas gingivalis or Actinobacillus actinomycetemcomitans. Peptostreptococcus micros occurred in high proportions in seven of the eight patients with premature membrane exposure and inadequate osseous healing. These findings associate putative periodontal pathogens with unsuccessful guided bone regeneration. The control of periodontal pathogens in the oral cavity prior to placement of barrier membranes around implants might increase the prognosis of osseous regeneration.

Adolescent↗