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Biomedical subjects

J Shapira

Publications and source records attributed to J Shapira.

At least 127 records · Page 7Linked to original sources
PubMed1980

Bizarre urologic manifestations of pancreas carcinoma.

A 62-year-old patient presented with fever and abdominal pain. Urinary retention and bilateral hydronephrosis were caused by bladder malfunction due to infiltration of the bladder wall by metastases from a carcinoma of the head of the pancreas. Both ureters were free. A previous choledochoduodenostomy prevented the development of jaundice.

Carcinoma↗
PubMed1979

Regression of amyloidosis secondary to granulomatous ileitis following surgical resection and colchicine administration.

A patient with nephrotic syndrome was found to have amyloidosis secondary to an otherwise asymptomatic Crohn's disease. Resection of a major portion of the affected bowel and long-term colchicine therapy were followed by a complete clinical remission of the nephrotic syndrome, most probably due to a significant resolution of amyloidosis. The combination of resection of affected bowel segments, together with long-term colchicine therapy may offer a better prognosis than either method alone.

Adult↗
PubMed1977

Probability of survival in hypertensive and nonhypertensive patients on maintenance hemodialysis.

The actuarial survival rate for 58 unselected patients who entered a program of maintenance hemodialysis and transplantation was found to be 43.0 +/- 8.3 (SE)% for the six-year period of observation. The survival rate was considerably lower in hypertensive patients as well as in patients with familial Mediterranean fever with amyloidosis, all of whom were nonhypertensive. When the patients with familial Mediterranean fever were excluded from the non-hypertensive group, the expected survival rate of this group became greater than that of the hypertensive group, the difference being about 25% in five years and about 50% in six years. This difference in the survival rate approaches that between normotensive subjects and untreated severely hypertensive patients in the general population. It is concluded that hypertension is a serious limiting factor in the survival of patients on chronic hemodialysis, and that the difference in survival between the hypertensive and the non-hypertensive patients is attributable to hypertension.

Adolescent↗
PubMed1976

High renin activity accompanying angiotensin II inhibition in rats with ischemic renal failure.

Acute renal failure was produced in rats by right nephrectomy and total occlusion of the left renal artery for 70 min. Angiotensin II competitive inhibitor, P113 (1-sar-8-ala-angiotensin II), was administered intravascularly for 100 min, starting 15 min before the clamping of the renal artery. A marked rise in plasma renin activity was observed 15 min after declamping and was significantly higher in the P113-treated rats than in saline-treated animals. The rise in plasma renin activity was observed 15 min after declamping and was similar in the two groups, indicating that P113 does not prevent the development of acute renal failure in this experimental model. It is suggested that the marked rise in plasma renin activity may be due to interruption of the normal feedback mechanisms which suppress renin release, as a result of occupation of the angiotensin II receptor sites by P113.

Acute Kidney Injury↗