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Biomedical subjects

J Serrano

Publications and source records attributed to J Serrano.

At least 199 records · Page 11Linked to original sources

Alpha-adrenergic blockers on ventricular automatism in rat heart.

The role of the alpha-adrenergic receptors in the genesis of cardiac arrhythmias induced in the isolated rat right ventricle has been studied. The administration of six alpha-adrenergic blocking agents (phenoxybenzamine, dibenamine, phentolamine, tolazoline, azapetine and SY-28) did not alter the automatism induced. Even when can not be excluded the existance of alpha-adrenergic receptors in the rat ventricle, it is clear that alpha-blocking drugs are ineffective to abolish the arrhythmias induced by an increase in the activity of the Purkinje fibers.

Adrenergic beta-Antagonists↗