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Biomedical subjects

J Seoane

Publications and source records attributed to J Seoane.

49 records · Page 3Linked to original sources
PubMed1985

Electrocardiographic findings in acute right ventricular infarction: sensitivity and specificity of electrocardiographic alterations in right precordial leads V4R, V3R, V1, V2, and V3.

To determine the sensitivity, specificity, predictive value and diagnostic efficiency of electrocardiographic alterations in the diagnosis of acute right ventricular infarction, 43 autopsy patients with acute myocardial infarction and an electrocardiogram including 12 leads plus leads V3R and V4R were studied. Group A included 21 patients with right ventricular infarction, of whom 14 (group AI) had posterior and 7 (group AII) had anterior right ventricular infarction. Group B included 22 patients without right ventricular infarction. Excluding group AII patients, the sensitivity of the presence of a Q wave reached 78.6% in lead V4R and decreased in leads V1 to V3; its specificity was low in all the leads. The sensitivity of ST segment elevation reached 100% in lead V4R and decreased in leads V1 to V3; its specificity was highest (68.2%) in leads V4R and V3R, its negative predictive value was 100% and its diagnostic efficiency was 80.6%. The criterion of ST segment elevation in lead V4R being higher than that in leads V1 to V3 was less sensitive (78.6%) than ST segment elevation in lead V4R alone, but its specificity reached 100%, its positive predictive value 100% and its diagnostic efficiency 91.7%. In conclusion, there are no electrocardiographic criteria to identify anterior right ventricular necrosis, but posterior right ventricular necrosis may be identified by the presence of a Q wave or ST segment elevation in the right precordial leads, reaching the highest sensitivity and specificity in lead V4R. The criterion of ST segment elevation in lead V4R being higher than that in leads V1 to V3 offers the highest specificity and efficiency in the diagnosis.

Acute Disease↗
PubMed1980

[Comparative study between HBsAg positive and HBsAg negative panarteritis nodosa in a series of 25 cases (author's transl)].

Clinical symptoms, biochemical analyses, immunologic status and angiographic findings corresponding to seven HBsAg positive patients with panarteritis nodosa and to 16 HBsAg negative patients with panarteritis nodosa have been compared. HBsAg positive cases showed a statistical significant higher incidences of Raynaud's phenomenon (p less than 0.05) and cardiopathies (p les than 0.05), as well as high occurrence of blood hypertension, artropathy, liver involvement and peripheral neuropathy. Significant differences in relation to cell immunity were not found. Humoral immune disturbances were more common among HBsAg positive patients, being hypergammaglobulinemia (p less than 0.01), IgM increase and decrease of complement factors (C3, C4 and C3PA) the most frequent abnormalities recorded. Angiographic studies revealed a high incidence of microaneurisms for the HBsAg positive group.

Adolescent↗
PubMedDate not supplied

[What is the best way to recruit patients for primary care programs of children's oral health?].

OBJECTIVE: To analyse the results obtained by two systems of recruiting patients in terms of: number of patients recruited, number of consultations requested, and number of half-yearly check-ups performed. DESIGN: Retrospective and observational. SETTING: Primary care. PATIENTS: 1868 school-children from 6 to 14 in the Burela Health Area (Lugo). MAIN RESULTS: The system based on the health centre recruited 616 children and led to 759 requests for consultation; whereas the system based on the school recruited 1252 children and 507 requests (123% vs 40%; p < 0.05). 23% of the school-children attended their half-yearly check-up under the first system, while 21% did so under the second. CONCLUSIONS: Check-ups of children at the health centre in their parents' presence seems to answer better the objective of introducing the bucco-dental health programme into the Health Area's child population.

Adolescent↗
PubMedDate not supplied

Esophageal pH monitoring of postprandial gastroesophageal reflux. Comparison between healthy subjects, patients with gastroesophageal reflux and patients treated with Nissen fundoplication.

To analyze postprandial gastroesophageal reflux by means of ambulatory gastroesophageal pH monitoring for 24 h, four groups were studied prospectively: group A: 22 healthy volunteers; group B: 31 consecutive patients undergoing medical treatment for gastroesophageal reflux, group C1: 20 consecutive patients with symptomatic reflux awaiting surgical treatment by means of Nissen fundoplication (pre-Nissen evaluation) and group C2: group C1 patients reevaluated 6 months postoperatively (post-Nissen evaluation). Gastro-esophageal pH, as a measure of post-prandial reflux following the main meal of the day was evaluated by the Kaye test. In groups B, C1 and C2, esophageal manometry was also performed. Gastroesophageal pH monitoring revealed significant qualitative as well as quantitative differences in postprandial gastroesophageal reflux experienced by healthy subjects (group A) and surgically treated patients (group C2) compared to patients with pathologic reflux (groups B and C1). The postprandial reflux was significantly more acid and more important (Kaye's test value) in groups C1 and B than in groups A and C2. There were no differences in postprandial reflux between healthy subjects and patients treated by Nissen fundoplication (group C2). Only the pressure and length of the lower esophageal sphincter (LES) showed differences after Nissen fundoplication. We conclude that patients with pathologic reflux have more severe postprandial reflux than normal subjects; Nissen fundoplication corrects the degree of postprandial reflux to a normal range by elevating the LES pressure (11.3 x 1.4 vs. 22.4 +/- 1.6 mm Hg; p < 0.001) and length (2.7 +/- 0.2 vs. 3.7 +/- 0.1 cm; p < 0.001) in our patients.

Adolescent↗
PubMedDate not supplied

[Styles and types of quality of life in the Seville Questionnaire].

The Sevilla Scale of Quality of Life is composed by two scales: the Scale F or scale of favourable aspects and the Scale D or scale of unfavourable aspects. This work elaborates some conceptual procedures and some operative strategies to interpret in a complex way the quality of life. We build a unique and global punctuation for the CSCV that we denominate PCV, and that it is the result of other partial scores; we also outline the analysis of the dispersion matrix of the PCV like a system to differentiate styles different from quality of life. We use the factor structure of the CSCV to represent each subject in a three-dimensional space by means of two points, the favourable aspect and the unfavourable one; the geometric distance between both points represent another conceptual shade to interpret of the types of quality of life. The necessity is underlined of guaranteeing the utility of these procedures by means of future empiric analysis, with samples of subject so much normal as pathological.

Humans↗
PubMedDate not supplied

Prevalence of diabetes mellitus amongst oral lichen planus patients. Clinical and pathological characteristics.

OBJECTIVES: The aim of this study has been to define the prevalence of DM (considered according to the ADA-97 criteria) in OLP patients and also to investigate the existence of clinical and pathological differences between OLP patients with or without DM. STUDY DESIGN: Sixty-two patients suffering from OLP according to clinical and pathological criteria were selected to enter the study and classified after the DM diagnosis guidelines suggested by The American Diabetes Association (ADA-1997). The variables considered for each patient were: age, sex, clinical presentation, extension of the lesions, location of the lesions, number of locations, Candida albicans colonization, and density of subepithelial inflammatory infiltrate. RESULTS: Up to 27.4% of OLP cases were associated to type 2 DM (DM2) and 17.7% were related to an impaired fasting glucose (IFG). The mean age of the DM2-associated OLP group was significantly higher than the non-diabetic group's. No significant differences could be observed in terms of clinical and pathological features between diabetic and non-diabetic OLP patients. CONCLUSION: The high prevalence of hydrocarbonate metabolism disorders observed in OLP patients justify the use of FPG for screening of DM2 in these patients.

Diabetes Complications↗
PubMedDate not supplied

Do ambulatory-use Platelet-Rich Plasma (PRP) concentrates present risks?

Platelet-Rich Plasma (PRP) concentrates have been widely used in the past decade as a complement to tissue regeneration procedures. The authors who have clinically used PRP refer no risk of infection, disease transmission, or undesirable effects. Nevertheless, there have been reports on the over-expression of growth factors (GFs) and their receptors related to tumour and dysplastic tissues. This has led to evaluation of the possible coincidences between carcinogenesis and the mitogenic pathways employed by GFs. The present study provides a review of the literature on the possible effects of the therapeutic uses of GFs (including PRP) in relation to carcinogenesis, their influence upon tissues with epithelial dysplasia or oral carcinoma, and their relation to tumour growth and infiltration.

Ambulatory Care↗
PubMedDate not supplied

Survival to oral cancer. A study of clinical risk markers with independent prognostic value.

BACKGROUND: The aims of this study have been to describe survival to oral cancer and to identify clinical variables with independent influence on its prognosis before treatment. METHODS: 94 oral cancer patients treated during 1991-99 entered the study. The variables considered were: age, sex, location of the lesion, clinical presentation, symptoms, TNM classification, months elapsed since treatment and ploidy pattern. A descriptive study of the data was performed, along with a survival analysis using Kaplan-Meier curves (log rank test for comparison among curves) and single and multivariate Cox regression. RESULTS: Multivariate analysis recognized a prognostic value for the age of the patient (OR = 1.06; CI95%: 1.02-1.09) and also for tumour size. Tumour stage resulted also selected, but its predictive value was lower than size's, so it was excluded from the predictive model. No statistically significant differences in terms of survival were identified on the rest of variables considered in the study. CONCLUSIONS: This study suggests the need for considering age and tumour size as the most relevant clinical variables for predicting survival to oral cancer at the time of diagnosis.

Adult↗
PubMedDate not supplied

[Malignant angular cheilitis].

A case of chronic angular cheilitis is reported. Candida albicans was isolated repeatedly and the process developed into epitheliomatous carcinoma. The etiopathogenic role of Candida albicans and possible mechanism of action are discussed.

Aged↗