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Biomedical subjects

J Seitchik

Publications and source records attributed to J Seitchik.

6 recordsLinked to original sources

A computer-based obstetric data retrieval system.

A computer-based obstetric patient data retrieval system is described which permits physicians with no prior computer knowledge or experience to access a patient data base. The advantages are minimal physician instruction, opportunity to examine maternal and neonatal outcome of defined diagnostic or therapeutic subsets of the data base, and rapid recall of individual patients' data, without need for continuous assistance from computer specialists. Disadvantages are the costs and our inability to interface our medical information with hospital business office data. Two brief examples of use of the system are provided.

Computers

Intrauterine pressure wave form characteristics of successful and failed first stage labor.

A retrospective study was designed to contrast the intrauterine pressure wave form characteristics of hypocontractile labor in patients with and without obstruction and before and after oxytocin therapy. No differences were observed between the patient groups (vaginal delivery vs. cesarean section), either before or after oxytocin. Problems in defining adequate contractility in patients with possible obstructed labors are discussed, and new parameters of potential value are identified.

Cesarean Section

Oxytocin-induced uterine hypercontractility pressure wave forms.

To identify similarities and differences between uterine contractions in patients with spontaneous labor, oxytocin-corrected hypocontractility, and oxytocin-induced hypercontractility, measurements were made of specific characteristics of the intrauterine wave form, including pressure, rate of change of pressure, and duration. Contractions from oxytocin-treated patients differed from contractions of those with spontaneous labor in their disproportionately high rates of rise of the pressure. The time to reach the maximum rate of the pressure--the start-up time--was reduced in oxytocin-induced hypercontractility. The data demonstrate that the contractions of spontaneous labor and oxytocin-augmented labor are not identical, and the physiologic implications are discussed.

Female

Intrauterine pressure wave form characteristics in hypocontractile labor before and after oxytocin administration.

The data demonstrate that the contractions of hypocontractile active labor and normal spontaneous labor are different in several measures in addition to maximal amplitude. Furthermore, when the pathophysiology is corrected by the use of oxytocin, the contractions resemble those of normal spontaneous labor except in the maximal rate of tension development. Our data tend to support the subcellular model of uterine contractility, although the incompleteness of these models limits interpretation.

Adrenocorticotropic Hormone

Intrauterine pressure wave-form characteristics of spontaneous first stage labor.

Intrauterine pressure wave-form parameters were measured in 827 contractions obtained from 26 patients in spontaneous labor. The coefficients of correlation between the maximal and minimal rates of pressure change and the maximal pressure amplitude were 0.78 and 0.63, respectively, and greater than or equal to 0.70 in 22/26 patients. Contractions partitioned into decile statistical groups of the pressure amplitude and both maximal and minimal rates. A linear relationship between these parameters has therefore been established. Contractions of greater amplitude tend to be longer, but the relationship between duration and amplitude is nonlinear with a limiting maximum contraction time. The duration of the midportion of the pressure wave appears invariate with respect to wave amplitude and only start-up and termination times increase with increasing amplitude. Mean values and standard deviations of the maximal amplitude (40.4 +/- 16.9mmHg). the maximal (2.4 +/- 0.9 mmHg/s) and minimal (-2.1+/- 0.9 mmHg/s)rates of pressure change, and the total duration of contractions (68.6 +/- 17.8s) were determined.

Female