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Biomedical subjects

J Schaffner

Publications and source records attributed to J Schaffner.

9 recordsLinked to original sources
PubMed1994

Colon adenocarcinoma in HIV infection: a case report and review.

Gastrointestinal adenocarcinoma is a disease seen uncommonly in HIV-infected patients. The present case is that of a 25-yr-old black male who was HIV positive and developed right-sided colon adenocarcinoma. This case is an example of the growing number of adenocarcinomas of the gastrointestinal tract being reported in HIV patients. Cases of gastric, pancreatic, and colonic adenocarcinoma in HIV patients are reviewed herein. It seems possible that HIV may play an etiologic role in the increased chance of developing gastrointestinal adenocarcinoma.

Adenocarcinoma↗
PubMed1987

Use of amylase isoenzymes in laboratory evaluation of hyperamylasemia.

Amylase isoenzyme analysis by agarose gel electrophoresis and lipase concentration by radioimmunoassay were performed in 98 consecutive hyperamylasemic patients. Total pancreatic (P-type) isoamylase was elevated in 89% of patients with clinical evidence of pancreatitis, and in only 11% of those without pancreatitis. Of 43 patients in whom the clinical diagnosis was obscure, 44% demonstrated an increase in pancreatic amylase and three (7%) had an increase in salivary (S-type) amylase. Lipase concentration by radioimmunoassay correlated well with lipase activity (r = + 0.69, P less than 0.05) and was as effective as amylase isoenzymes in distinguishing patients felt likely to have pancreatitis from those who were unlikely. Amylase isoenzymes or serum lipase concentration may be useful tests in the laboratory evaluation of hyperamylasemia when the etiology is obscure.

Adolescent↗
PubMed1986

Acute gastrointestinal bleeding.

Acute gastrointestinal bleeding remains a major cause of morbidity and mortality. Recent diagnostic and therapeutic advances may play a significant role in the care of the bleeding patient.

Angiography↗