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Biomedical subjects

J Sayag

Publications and source records attributed to J Sayag.

At least 55 records · Page 3Linked to original sources
PubMed1988

[General review: classification of urticaria and angioedema].

The authors propose a classification of urticarias and angio-oedemas according to two criteria, physiopathological and etiological. In the first group they identify three subgroups; immunological, non-immunological and idiopathological. In the second group they classify the facts into 12 sub-groups, which are detailed.

Angioedema↗
PubMed1988

[The G.E.R.U. retrospective study of 400 cases of urticaria].

The authors report on a study with computerised results of 400 urticaria and/or angioedema cases, which were explored in single dermatology center (Pr. J. SAYAG) by the members of GERU. The study was managed with a computerised file and was processed with Sesame software. The figures achieved are related to semilogic and paraclinical data and to etiological factors.

Adolescent↗
PubMed1988

[The association of dermatomyositis and toxoplasmosis].

IF: negative test: less than 10 UI/ml; doubtful test 10-100 UI/ml; positive test greater than 100 UI/ml. HA: negative test: less than 8 dilutions; doubtful test 16-24; positive test greater than 128. The antibodies kinetics vary with the pattern of the infection (primary infection or reinfection), with the method of identification, and with the subjects. In the case of primary infection, the IgM appear since the first week following the acquisition of the infection; they reach their highest titre at the first month (variability: 15th day-3rd month); they disappear during the fourth month (variability: 2-9 months). The antibodies detected by HA after 2 ME must be reduced by at least 3 dilutions to be significant. The IgG appear later. They are detected at the beginning of the second week by IF or of the 4th month by HA, reach their highest titre at the 4th month by IF (variability: 2-9 months) or at the 9th month by HA (variability: 4th month-2nd year); they then decrease to reach lower titres within the space of 1 or 5 years. The antibodies detected in the case of reinfection are usually of higher titre with a steeper rate of increase, and are more persistent than following a primary infection.

Dermatomyositis↗
PubMed1987

[Oral provocation tests (OPT) in the skin pathology of children].

The purpose of oral food challenges is to detect food intolerance. Challenges of food additives and drugs are not often used in children. The authors report methods and protocols that they used for food, food additives and contaminants and emphasize the potential dangers of these tests. Atopic diseases and chronic urticaria are the principal indications. Cow's milk, eggs and fish are the allergens that are most often incriminated. Oral challenges are only to be done as part of an integrated investigation together with skin tests, in vitro tests and a study of intestinal permeability. Food avoidance and therapy should be decided after the challenge data are available.

Administration, Oral↗
PubMed1987

[Chronic urticaria--an inventory proposed by the Urticaria Study and Research Group].

The Urticaria Study and Research Group (Groupe d'Etudes et de Researches de l'Urticaria, G.E.R.U.) was formed in the Dermatology Department of the Hôpital Michel Levy in 1983 and now it continues to operate in the new Dermatology Department of the C.H.U. Timone Adultes. This has been possible because in four years 400 cases of urticaria have been seen and computerized information on these will appear in the next issue. As a result of this experience, we have been able to lay out a prospective study and develop a rigorous methodology.

Chronic Disease↗
PubMed1986

Detection of HTLV-I (human T-cell lymphotropic virus, type I) proviral DNA in leukemic cells from a French patient with Sezary syndrome.

Human T-lymphotropic type I (HTLV-I) proviral sequences were detected in leukemic cells of a patient living in Marseilles (south of France) and suffering from Sezary syndrome. He did not have any travel history outside France and did not receive blood transfusion or hepatitis B vaccination. This case of HTLV-I positive Sezary syndrome is the first one described outside the known endemic regions for HTLV-I. Moreover, this patient was found to be negative for viral antibodies. This observation should therefore stimulate new and thorough analysis of the association of this human retrovirus with leukemia and lymphoma in the Mediterranean region, both by seroepidemiological and molecular biology techniques.

Aged↗
PubMed1986

[The Langerhans cell. Recent immunologic achievements].

The epidermal Langerhans cells has been keeping, most of its secrets for about a hundred years since its first description in 1868. Its characterization in electron microscopy by Birbeck and then the use of histoenzymology (ATPase) and monoclonal antibodies (against HLA-DR, T6, LCA, C3b...) brought a new great interest on its study. The Langerhans cell must play an important immunologic role in the epidermis because of its responsibility in the antigenic information of the lymphocytes; in this way it may represent the specific epidermal differentiation of the monocyte-macrophage cell type, which are all bone-marrow derived cells. The epidermal Langerhans cell is one of the most important links in the elicitation of contact dermatitis. Recent trends about its metabolism, antigens and functions are reviewed and discussed.

Humans↗
PubMed1985

Multicenter clinical evaluation of a hydrocolloid dressing for leg ulcers.

The need for a moist environment for the normal healing process led to the development of occlusive dressings. Results from this study support the contention that a moist wound environment is favorable to the healing process in humans as well as in animal models. Hydrocolloid dressings are effective in the practical daily management of chronic and even refractive ulcerations of the lower extremities and offer a time-saving treatment alternative with a high degree of patient acceptability.

Adolescent↗