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Biomedical subjects

J Sauvegrain

Publications and source records attributed to J Sauvegrain.

At least 37 records · Page 2Linked to original sources
PubMed1981

The changing aspects of cholelithiasis in children through a sonographic study.

Ultrasonography has made the study of the biliary tract easier. This may account for an apparent increase in the incidence of cholelithiasis in children. Twenty-nine cases of biliary stones, mostly gallstones, were seen in a 3 year period. More than half of the cases were secondary to a definite cause, among which the interruption of the enterohepatic circulation of bile salts should be emphasized. The etiological factors of biliary stones and biliary sludge appeared identical in our material.

Adolescent↗
PubMed1981

Calcifications of the hip in infants and children. New cases and long-term follow-up.

10 cases of calcification of the peripheral cartilaginous contour of the femoral head in infants are reported. In 7 cases calcification were discovered by chance at a radiological examination done for another purpose. In 3 cases the examination was done for limp or pain in the hip. In this material are included the long term follow-up of the first 4 cases reported by one of us in 1968. The follow-up in our series ranges from a few months to 15 years. The clinical sequelae are minimal at the moment: slight decrease of abduction and internal rotation. The radiological follow-up shows a slow disappearance of calcification, a premature fusion of the physis, a coxa magna, a broadening and shortening of the femoral neck. These residual radiological anomalies, in spite of a good clinical state at the moment, are worrying for future of these hips. The etiology is unknown, but these calcifications are acquired and there are good reasons to think they are iatrogenic, probably secondary to an inadvertent injection into the hip joint at the time of an intravenous femoral infusion of a drug toxic for the hip cartilage. It seems reasonable to avoid the femoral route for intravenous infusion of drugs in newborns and infants.

Calcinosis↗
PubMed1981

[Serum concentrations of vitamin D metabolites in idiopathic juvenile osteoporosis (author's transl)].

This report concerns a 13 year old girl with the clinical and radiological features of mild idiopathic juvenile osteoporosis. In this patient, no alteration was detected in serum calcium (total + ionized) and phosphorus concentration, serum alkaline phosphatase activity, nor in urinary calcium and phosphorus excretions. Plasma concentrations of cortisol were normal during daytime and sleep. Circulating immunoreactive parathyroid hormone was normal or low. The serum 25-(OH)D and 24,25-(OH)2D concentrations were below the normal range, and the 1,25-(OH)2D concentrations were above the normal range (720 pmol/l) at the beginning of the investigation. All vitamin D metabolites concentrations returned to normal values at the time of radiological recovery and after calcium and 25-(OH)D3 supplementation. A possible relationship between alterations of bone and of circulating vitamin D metabolites is discussed.

Adolescent↗
PubMed1980

[Radiation lesions of the digestive tube after irradiation of the abdomen in children: radiological appearances (author's transl)].

The contribution of radiological examinations to the evaluation of radiation lesions of the digestive tube in 17 children is discussed. The lesions observed were stenosis, submucous infiltration, and mesenteritis from vasculitis. Ali the patients had been treated with high irradiation doses varying from 3,000 to 5,500 rads. Clinical manifestations appeared after intervals of from 2 months to 13 years, but the anatomical lesions seemed to occur early and to show little change once they were established. Except when an acute occlusion was present, radiological examination consisted of a barium meal and follow through, able to demonstrate anomalies in the folds, stenosis, dilatation, or thickening and matting of the intestinal loops.

Adolescent↗
PubMed1979

[Biliary lithiasis in cystic fibrosis. Study of the bile salts in the serum and in the bile in one case (author's transl)].

Biliary lithiasis was discovered in a girl aged 11 suffering from Cystic Fibrosis and who underwent partial small bowel resection for meconium ileus. A cholecystectomy was performed at 15. Examination of the stones showed that they were composed of cholesterol and chemical examination of the bile showed an increase of phospholipids and a decrease in bile salts. There was also a modification of the ratio (Formula: see text) in the serum and the bile. All those factors contribute to the insolubility of cholesterol and to the formation of lithiasis. For all those reasons, the authors recommend a regular radiologic surveillance of the gallbladder in Cystic Fibrosis.

Adolescent↗
PubMed1979

Radiological aspects of the small bowel after extensive resection in children.

The authors present radiological aspects of small bowel after extensive resection. They describe the main phenomena related to compensatory hypertrophy: dilatation of the loops, mucosal fold-thickening and motor disturbances. The main complications demonstrated by the radiological examination are presented; gallstones, non-functioning anastomosis, bacterial overgrowth.

Adaptation, Physiological↗
PubMed1979

[Intestinal obstruction with feces (meconium ileus equivalent) in the course of mucoviscidosis. Radiographic diagnosis (author's transl].

Meconium ileus equivalent is a late intestinal occlusion occurring in patients suffering from mucoviscidosis. Three cases are reported in children aged, respectively, 3 years, 6 years and 10 years. In one of the observations (three year old girl), the intestinal obstruction with feces was first manifestation of a mucoviscidosis that was previously undetected. The radiological signs are identical to those found in cases of neonatal meconium ileus: intestinal obstruction and accumulation of closely spaced matter in a distended ileum (terminal part). As in cases of meconium ileus without complications, treatment consisted of enemas with water-soluble products. The high osmotic pressure of these products made it possible to remove the obstruction.

Child↗