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Biomedical subjects

J Sargent

Publications and source records attributed to J Sargent.

At least 55 records · Page 3Linked to original sources

Physical training and fasting serum insulin levels in sedentary men.

The present study examined fasting serum insulin levels in relation to body composition and dietary intake during the initial 4 weeks of a 12-week physical training programme in 26 previously sedentary men. Fasting serum insulin concentrations decreased markedly during the first 4 weeks of training and remained at these reduced levels for the rest of the study. The early fall in serum insulin concentration was significantly correlated with the concomitant decrease in body fat, the increase in lean body weight and the age of the subjects. Body weight and reported dietary intake on the other hand, did not change significantly over this period. These results indicate that the decrease in fasting serum insulin in previously sedentary men with physical training is associated with the concomitant changes in body composition. Increased muscle tissue in particular may contribute to this training-induced decrease in serum insulin.

Adipose Tissue↗

Outpatient treatment of anorexia nervosa.

The authors discuss outpatient treatment of the anorectic in terms of a process catalyzed in therapy sessions that takes place throughout the patient's daily life. The goal to reverse the physical and psychological symptoms of the disorder within the natural context of family, school or work, and community while enhancing development and adaptation is clearly defined. Treatment is described as holistic; the patient's mind and body are treated in concert.

Adolescent↗

Behavior and diabetes care.

Juvenile diabetes presents both the child and the family with psychosocial challenges. Control of the illness and the development of the diabetic child depend on how effectively the family meets these challenges. Maladaptive family interaction can lead to behavioral difficulties as well as poor diabetic control. Problems of recurrent ketoacidosis and noncompliance are highlighted with case histories.

Adolescent↗

The sick child: family complications.

Pediatric care for chronic illness necessarily involves the sick child's family. Effective medical care includes knowledge of the family as a social system and an understanding of the challenges that chronic illness in childhood brings to both the ill child and his family. Several potential difficulties may arise for the family, including overprotection of the ill child, the development of a split in the marriage as one parent cares exclusively for the ill child, and disruption of the remainder of family life. Specific characteristics of family interaction have been associated with varieties of medical difficulties and psychosocial maladaptation for the child. Pediatric care should include family interventions which enhance the family's ability to manage the chronic illness as well as improve their child's psychosocial status. Structural family therapy has been demonstrated to be effective in treating severe family maladaptation to chronic illness and in significantly improving the child's condition. The tenets of family therapy for maladaptation to chronic illness are also reviewed.

Child↗

The bacteriologically battered baby: another case of Munchausen by proxy.

We present a case in which a mother who had had self-inflicted infections as a teenager also caused life-threatening infections in her year-old child. After testing for and treating various immunologic deficiencies without success, it was apparent that the infection was caused by contamination of intravenous sites. Strict isolation of the patient, with restricted and observed visitations by the mother, was the critical step in stopping the infections. Because the woman took her child to several emergency departments, this case is presented to alert emergency personnel to this entity and to explain some of the dynamics and the social issues that cause the problem.

Adult↗

The application of a single radial haemolysis technique to foot-and-mouth disease virus-antibody study.

Experiments are described for the evaluation of the single radial haemolysis (SRH) technique applied to FMD virus, using a method involving the coupling of either antigen or antibody to sheep erythrocytes. The antigen coupling method detected specific antibody but the technique was found to be impractical as it gave reproducible results only with purified virions. However, the antibody coupling technique gave clear zones of lysis using tissue culture harvest virus as well as purified virus, and was also shown to be type specific for detecting antigen. A comparison of the SRH test with the single radial immunodiffusion (SRID) and complement fixation (CF) tests indicated that the SRH was a more sensitive test for assaying FMD antigen than either the SRID or CF tests. Although the SRH and SRID test results correlated well, those obtained in the SRH and CF tests did not. The test was not found to be superior to the CF test in assessing the quality of antigen since, like the CF test, it reacted both with the immunizing 140S antigen and the non-immunogenic 12S protein subunits.

Antibodies, Viral↗

Familial inverted choreoathetosis.

We present a family with infantile onset of progressive choreoathetosis. The movements affected the legs predominantly and also impaired gait. No dementia, seizures, or rigidity was noted. Inheritance was autosomal dominant. This new familial movement disorder can be differentiated easily from other hereditary choreas.

Athetosis↗

Nosocomial Klebsiella infections in an intensive care nursery.

Nosocomial infections in an intensive care nursery (ICN) due to kanamycin-resistant Klebsiella pneumoniae during a four-month period with an infection rate of 12% and mortality of 47% are reported. Emergence of this organism was thought to be due to the widespread use of kanamycin. Transmission probably occurred via hands of personnel contaminated during care of colonized or infected infants. Control measures advocated are better handwashing technic and discriminate use of antibiotics. This report emphasizes the need for awareness of this continuous threat and for infection surveillance in an ICN.

Asepsis↗