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Biomedical subjects

J Sans

Publications and source records attributed to J Sans.

26 records · Page 2Linked to original sources
PubMed1979

Proliferative index estimated by chromatin pattern analysis.

Chromatin pattern analysis at different density thresholds in Feulgen-stained meristems stimulated to proliferate by water inbibition, allows to estimate a proliferative potential index (PPI) which is a much earlier indicator of changes in proliferation than conventional labelling and mitotic indices. The PPI is but the ratio G1 cells to total 2C cells (or G2 to 4C cells, when cells also digress from the post-replicative stage of the cycle). The method is based in the fact that G1 and G2 cells have larger projected nuclear area and smaller dense chromatin area than their conterpart non-proliferating G0 and G0,2 cells.

Cell Cycle↗
PubMed1979

Cell proliferation in the mouse parotid gland after unilateral parotidectomy.

Unilateral parotidectomy with or without total submandibulectomy has been used to induce cell proliferation in mouse parotid gland. Maximum DNA synthesis and mitosis were recorded four and five days after the operation. The double operation increased the proliferative response. Such proliferative stimulii was not accompanied by secretion and was sex independent. On the other hand, the response decreased with age. RNA and protein synthesis inhibitors showed that the stimulation of DNA synthesis depends on early protein synthesis, which seems to be synthesized on a preexisting template.

Animals↗
PubMed1979

Go and Go,2 cells as identified by their chromatin pattern in dormant and proliferating meristems.

Microdensitometry at different density thresholds of Feulgen-stained nuclei shows that both 2C and 4C dormant cells of the unsprouted root of Allium cepa L. bulbs have a smaller nuclear volume and a larger amount of dense chromatin than their counterpart G1 and G2 cells of the proliferating root. The analysis seems to differentiate between cells in the proliferate compartment from those in the non-proliferative compartment (Go and Go,2 cells).

Cell Cycle↗
PubMedDate not supplied

Unilateral pulmonary artery agenesis presenting with hemoptysis: treatment by embolization of systemic collaterals.

Systemic-to-pulmonary collateral vessels and shunts develop in patients with isolated unilateral absence of a pulmonary artery (IUAPA). Two cases of IUAPA (right and left) with hemoptysis in adult life are presented. Selective embolization of these systemic vessels controlled hemoptysis successfully. These cases represent an example of an alternative treatment for this rare anomaly.

Adult↗
PubMedDate not supplied

X to Y spermatozoal ratio in normal and oligozoospermic human semen and its relationship to fertility parameters.

The ratio of X to Y spermatozoa in normo and oligozoospermic human semen is established with a fluorescent technic using quinacrine. The relationship between concentration of X and Y spermatozoa to factors that potentially control the fertilizing ability of spermatozoa (i.e. sperm count, vitality, motility and morphology) is analyzed. Out of a total of 44 samples (22 normo and 22 oligozoospermic samples) a ratio of 1:1 in X to Y spermatozoa is found in both groups. The frequency of X to Y spermatozoa in the evaculate is not related to sperm count. It is also independent from morphology, motility, and vitality of spermatozoa.

Cell Count↗