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Biomedical subjects

J Sandford-Smith

Publications and source records attributed to J Sandford-Smith.

3 recordsLinked to original sources

In situ degradation of 11/0 polyester (mersilene) suture material following cataract surgery.

Two hundred and ten patients (231 eyes) had their cataract sections closed with 11/0 polyester suture material over a 4 year period. Their case sheets were assessed to determine the number of eyes from which sutures had been removed prior to discharge, and for what reasons these sutures were removed. Ninety-seven patients (107 eyes) with sutures left in situ were further assessed to determine whether they were suffering from any suture-related symptoms and examined to determine the degree of clinical biodegradation experienced by the sutures. Six of these sutures were removed for electron microscopic examination. Of the 231 eyes initially included, 61 sutures (26.4%) had been removed prior to discharge. None of the 107 sutures examined showed evidence of clinical biodegradation; this was confirmed by electron microscopic analysis which showed only minimal erosion of sutures even after 48 months in situ.

Biodegradation, Environmental

Retrobulbar phenol injection in blind painful eyes.

Retrobulbar phenol injection was used as a neurolytic to manage blind chronically painful eyes in ten patients. The cause of the blind painful eye was absolute glaucoma in eight of the ten eyes. We used 1.5mL of 1:15 (6.7%) aqueous phenol solution in each case. None of the patients experienced any pain from the injection. Seven patients obtained complete pain relief after the procedure, and one patient had some improvement. We found a range of duration of pain relief of 4.5 to 48 months (mean, 15 months), which compares favorably with retrobulbar alcohol injection. We believe retrobulbar phenol injection is preferable to alcohol. It has the advantage of being less painful during injection because of its local anesthetic properties.

Adult