Exertional ventricular tachycardia.
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Biomedical subjects
Publications and source records attributed to J Salomon.
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Parents and patients in the Rhode Island Cystic Fibrosis Center were interviewed to determine the extent of compliance with various aspects of the therapeutic regimen. Current patterns of compliance were compared with retrospective clinic records of reported compliance up to 8 years prior to the time of study. Actual clinic attendance and reported compliance with medications were high. Patients reported significantly lower compliance with diet and chest physiotherapy. Most patients reported less compliance with chest physiotherapy at the time of study than 3 to 8 years earlier, regardless of the severity of their lung disease. Patients frequently reported self-medication with non-prescribed vitamins, antibiotics, or other drugs. Patients' perceptions of the severity of their disease and the possible adverse consequences of discontinuing therapy probably contribute to both good medication compliance and self-medication.
Rupture of the left ventricle following mitral valve replacement occurred in 2 women among 520 patients (0.4%) during a 17-year-period at the Beilinson Medical Centre. In one patient, a delayed, type II rupture, followed by immediate exanguination, resulted from a 31 mm cloth-covered Starr-Edwards prosthesis inserted in a normal sized left ventricle. In the second patient, an intra-operative type I rupture occurred as a result of an over-zealous resection of a heavily calcified valve and annulus. Repeated attempts at surgical repair were unsuccessful. A review of 46 previously reported cases revealed several other factors that might be responsible for this complication which carries a 40-100% mortality rte, depending on whether it is diagnosed intra-operatively or in the immediate postoperative period. These factors and the variety of surgical approaches used for the repair of this grave complication are discussed.
Biliary tract resistance was measured in 142 patients during cholecystectomy with the use of narcotic or nonnarcotic anesthesia techniques. If fentanyl citrate (narcotic) was used, there was no difference in the pressures measured in normal ducts between these cases and those patients receiving nonnarcotic anesthesia. When morphine sulfate was administered, the resistance exceeded normal values in five of seven patients with normal ducts.
The number of elderly patients living in institutions is increasing. Many of them are unable to maintain an adequate nutritional status because of: 1) neurologic deficits that preclude normal swallowing; 2) obstruction of the upper gastrointestinal tract; or 3) a systemic disease that has produced profound anorexia. This report presents the data on 106 permanent-feeding gastrostomies, performed with low morbidity and low mortality. Use of a gastrointestinal anastomotic stapling device greatly facilitated the operation. The permanent gastrostomy offers an effective means of providing adequate nutrition for elderly patients who otherwise cannot maintain the necessary nutritional status.
Marked peaking of the T waves later recognized as being due to hyperkalemia was noted in a patient with acute fluoride intoxication before developing refractory ventricular fibrillation. Such T wave changes have not been previously described in fluoride intoxication and should alert one to the presence of hyperkalemia complicating this condition, the presence of which may herald the onset of lethal ventricular arrhythmias.
We describe a microcomputer-based, stand-alone, on-line scheduling data entry and retrieval clinical data base system, specially tailored for a nuclear medicine department. It includes provision for free format clinical diagnostics text answers to each radioisotope scan. Such a system is currently installed at the Department of Medical Biophysics and Nuclear Medicine at the Hadassah University Hospital, and handles all the patient tests performed in this department. We feel that the design of an independent microprocessor-based system customized for one's department needs has indeed improved the quality of the clinical services, both in ensuring that the patient records are kept up-to-date and complete, and in providing, through fast interactive retrieval transactions, immediate answers for a given patient status.
Rest and exercise thallium 201 myocardial scintigraphy and multiple gated radionuclide angiography were correlated with the results of clinical status, exercise electrocardiography, coronary arteriography, and contrast left ventriculography in a series of 12 prospectively studied consecutive patients before and after aortocoronary bypass operation. Patients were divided into two groups based on a comparison between preoperative and postoperative 201T1 scintigrams. Group 1 (6 patients) demonstrated improved or normal postoperative perfusion scintigrams and excellent correlation between the site of a patent graft and the improvement in myocardial perfusion on the postoperative exercise scintigrams. Regional wall motion remained normal in 3 patients and improved in 3. In Group 2 (6 patients) the postoperative 201T1 scintigrams were unchanged or worse. Each patient demonstrated graft occlusion, graft stenosis, distal disease, or a perioperative myocardial infarction. No improvement in regional wall motion occurred in 4 of these 6 patients. Neither the symptomatic response to aortocoronary bypass operation nor the response to exercise testing successfully predicted graft patency.
Biliary tract resistance was measured in 142 patients at the time of cholecystectomy, using a simple technique in which contrast media is infused through the cystic duct at a fixed flow rate. A sharp demarcation exists between the resistance of patients with normal and abnormal common bile ducts. A resistance of less than 2.5 units was found in only one patient with a common duct abnormality, and the test was improperly performed in that case. Two patients with normal common ducts had resistance values of greater than 2.5 units, for a false-positive rate of 1.63%. Overall, the technique gave accurate results in 97.9% of the cases studied.
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Thirteen cases of diaphragmatic rupture following blunt trauma or gunshot wounds are presented. In 10 cases the diagnosis of diaphragmatic rupture was made immediately following the injury, and the defect was closed by primary diaphragmatic suture. In three cases, the diagnosis was delayed for 3 to 16 years after the initial trauma. In all of them, abdominal organs such as the colon or liver had migrated into the thoracic cavity. One of them had acute intestinal obstruction and died following several unsuccessful operations. The remaining two patients required plastic repair of the diaphragmatic hernia by a Dacron patch, and both recovered. The clinical and pathological aspects of diaphragmatic rupture, the importance of early diagnosis and surgical correction, and the surgical approach to this entity are considered. The use of Dacron fabric in delayed closure of diaphragmatic defects is described.
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A method is described for segmental esophageal replacement in dogs, with one of three types of tissue substitute: pericardium, fascia lata and aortic homograft. The experiments involving the thoracic esophagus failed owing to the development of acute mediastinitis and sepsis. The most promising results were obtained in animals in which an aortic homograft was used to replace the cervical sigment of the esophagus. Eight of the 12 animals with aortic homograft survived and gained weight until killed one to six months after operation. The overall results suggest that aortic homograft may have a potential clinical application in cases in which esophageal replacement is necessary.
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Two patients, who suffered from pericardial tamponade in the course of prophylactic anticoagulant treatment, are reported. The mitral valve had been replaced by a prosthesis in both cases. The diagnosis was suspected clinically and radiologically and proven by pericardiocentesis. One of the patients was treated by a percutaneously inserted small polyethylene tube for continous drainage and the other by thoracotomy and partial pericardiectomy. Both patients recovered and are at present asymptomatic. Th mechanism of bleeding patients receiving anticoagulant therapy is briefly discussed.
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