Anatomically corrected malposition of the great arteries in situs ambiguus with polysplenia.
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Biomedical subjects
Publications and source records attributed to J Salazar.
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Two cases of monoventricular origin of TAC arising from the right and left ventricle respectively are reported. The authors comment on their implications with respect to the embryology and definition of TAC.
The diagnosis of hepatic rupture in patients with pregnancy-induced hypertension (preeclampsia and eclampsia) is rarely made preoperatively. Diagnostic imaging can be utilized in some patients to confirm the preoperative diagnosis. Since hematoma formation precedes hepatic rupture, then, when diagnostic modalities such as sonography and computed tomography identify patients with hematomas, these patients are at risk of rupture, and should be hospitalized until the hematomas resolve.
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In addition to their usual diet, 17 lactovegetarian college students consumed 400 kcal of test foods per day containing one extra-large egg for three weeks and similar isocaloric eggless foods for an additional three weeks in a randomised double-blind crossover trial. Ingestion of the egg increased dietary cholesterol from 97 to 418 mg per day. Mean plasma low density lipoprotein (LDL) cholesterol was 12% higher (p = 0.005) and mean plasma apolipoprotein B was 9% higher (p = 0.007) when eggs were being consumed than during the eggless period. Mean plasma high density lipoprotein cholesterol, apolipoproteins A-I and A-II, very low density lipoprotein cholesterol, and total triglycerides did not change significantly. Thus, ingestion of egg seems selectively to raise cholesterol and protein in LDL particles in the plasma of free-living normal people. Plasma LDL may be more sensitive to cholesterol at low intakes than at moderate to high intakes.
The aberrant left pulmonary artery is a rare disease, producing severe respiratory failure in the neonatal period and early infancy. The diagnosis is easy and mainly done by X-ray. Although the main diagnostic procedure continues to be an elective angiography in the main pulmonary artery, the diagnosis may be confirmed by a contrast computerised axial tomography. It is necessary to use the classic tomography to rule out any associated tracheobronchial anomalies, and thus avoid other dangerous diagnostic procedures such as bronchoscopy and bronchography. Having reviewed previous publications, two cases are presented, one, being exceptional with left lung emphysema.
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Fluoroscopically guided percutaneous biopsy of pulmonary masses is an accepted procedure, but large neoplasms often have necrotic areas which, if aspirated, do not afford a pathologic diagnosis. Such tumors may require multiple punctures or procedures to establish a diagnosis. A prebiopsy contrast-enhanced CT scan selectively demonstrates the extent of peripherally located, viable tumor tissue. Three cases of initially frustrated lung biopsies in which viable, diagnostic tissue was localized for fluoroscopic aspiration using the contrast-enhanced CT scan are presented.
The arterial pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and plasma angiotensin II were measured in Wistar rats and 24 hours after arterial renal constriction by a clip (0.20 mm d.i.). The results were compared with those obtained in a sham operated group. The experimental group showed an increase in arterial pressure and total peripheral resistance without changes in heart rate, cardiac output and stroke volume. In hypertensive animals there was a greater level of plasma angiotensin II than in control group. These studies have demonstrated that 24 hours after renal arterial stenosis the increase in arterial pressure can be mediated by an increased activity of the renin-angiotensin system.
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Echocardiographic changes following surgical closure of atrial septal defect in 20 children are analyzed in order to get data for future noninvasive follow-up. After surgery, right ventricular diastolic dimension and index (p less than 0.001), tricuspid valve depth (p less than 0.01), septal depth (p less than 0.001), and right ventricular outflow tract (p less than 0.005) decreases the DE slope (p less than 0.025) and amplitude (p less than 0.05) of the mitral valve, and the left ventricular diastolic dimension and volume (p less than 0.001) increases. There was no case with type A paradogical septal motion after surgery; of the 6 cases with type B before surgery there was no changes in 3, al of them older than 8 years. The right ventricular diastolic volume overload produced by ostium secundum atrial septal defect, produce some echocardiographic changes which have a tendency to settle down after surgery. The finding of a dilated right ventricle with of without a type B paradogical septal motion, specially in children older than 8 years, is not necessarily indicative of a residual shunt.
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Histoplasma mediastinitis with complete or partial pulmonary artery obstruction due to compression and/or intraluminal granuloma was diagnosed in five patients and surgically verified in two. The patients, ages 12-27 years, had cough, dyspnea (four cases), and hemoptysis (two cases). Radionuclide imaging showed unilateral absence of pulmonary perfusion and minimal diminution of ventilation. Differentiation of this inflammatory process from other causes of ventilation-perfusion mismatch, for example, congenital hypoplasia and certain acquired causes of arterial obstruction, especially thromboembolism, may be possible by correlating radiographs, laminograms, and clinical history. Angiography can delineate the extent of perfusion impairment and may suggest its cause.
A case of endocardial cushion defect without ostium primum atrial septal defect associated with tetralogy of Fallot is presented. The echocardiogram is specially interesting showing two atrioventricular valves recorded simultaneously without an intervening ventricular septum, mitral continuity with the posterior semilunar valve and impossibility of recording the anterior semilunar valve. Findings similar to those of single ventricle with pulmonary stenosis. The anatomopathological findings and their possible embryonic basis are analyzed.
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